Morniflumate

Last updated
Morniflumate
Morniflumate.png
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 2-morpholin-4-ylethyl 2-{[3-(trifluoromethyl)phenyl]amino}nicotinate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.207.566 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C19H20F3N3O3
Molar mass 395.382 g·mol−1
3D model (JSmol)
  • FC(F)(F)c1cc(ccc1)Nc2ncccc2C(=O)OCCN3CCOCC3
  • InChI=1S/C19H20F3N3O3/c20-19(21,22)14-3-1-4-15(13-14)24-17-16(5-2-6-23-17)18(26)28-12-9-25-7-10-27-11-8-25/h1-6,13H,7-12H2,(H,23,24) Yes check.svgY
  • Key:LDXSPUSKBDTEKA-UHFFFAOYSA-N Yes check.svgY
   (verify)

Morniflumate is a nonsteroidal anti-inflammatory drug (NSAID). [1] [2] [3]

Related Research Articles

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<span class="mw-page-title-main">Semapimod</span> Chemical compound

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<i>Zingiber cassumunar</i> Species of flowering plant

Cassumunar ginger: Zingiber cassumunar, now thought to be a synonym of Zingiber montanum (J.König) Link ex A.Dietr., is a species of plant in the ginger family and is also a relative of galangal. It is called plai (ไพล) in Thailand, in addition to in Isan language and in northern Thai language. The rhizome of variant 'Roxburgh' is used medicinally in massage and even in food in Thailand, and somewhat resembles ginger root or galangal. In aromatherapy, plai oil is used as an essential oil and is believed to ease pain and inflammation. It is also known as ponlei (ពន្លៃ) in Cambodia.

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References

  1. Melica A, Donateo L, Gerardi R, Parenti M (1991). "[A new anti-inflammatory-analgesic-antipyretic, morniflumate, in the treatment of chronic recurring bronchitis]". Rivista Europea per le Scienze Mediche e Farmacologiche = European Review for Medical and Pharmacological Sciences = Revue Européenne Pour les Sciences Médicales et Pharmacologiques. 13 (1–2): 51–60. PMID   1796197.
  2. Civelli M, Vigano T, Acerbi D, Caruso P, Giossi M, Bongrani S, Folco GC (July 1991). "Modulation of arachidonic acid metabolism by orally administered morniflumate in man". Agents and Actions. 33 (3–4): 233–9. doi:10.1007/bf01986568. PMID   1659152.
  3. Schiantarelli P, Cadel S, Acerbi D (February 1984). "A gastroprotective anti-inflammatory agent: the beta-morpholinoethyl ester of niflumic acid (morniflumate)". Agents and Actions. 14 (2): 247–56. doi:10.1007/BF01966649. PMID   6608862.