Virginia Ruano Pascual and Paola Suárez were the defending champions, but Suárez did not participate due to injury. Ruano Pascual partnered Conchita Martínez, but lost in the first round to Jennifer Hopkins and Mashona Washington.
Martina Hingis and Mahesh Bhupathi defeated Elena Likhovtseva and Daniel Nestor in the final, 6–3, 6–3 to win the mixed doubles tennis title at the 2006 Australian Open. With the win, Bhupathi completed the career Grand Slam in mixed doubles, becoming the 14th player to do so. It was Hingis' first major mixed doubles title; she would later also complete the career Grand Slam in the discipline.
Wayne and Cara Black were the defending champions but lost in the second round to Mahesh Bhupathi and Mary Pierce.
Kimberly Po-Messerli and Nicole Pratt were the defending champions. They were both present but did not compete together.
Po-Messerli partnered with Corina Morariu, but lost in the quarterfinals to Virginia Ruano Pascual and Paola Suárez.
Pratt partnered with Alicia Molik, but withdrew before their second round match against Elena Dementieva and Janette Husárová.
Lisa Raymond and Rennae Stubbs won in the final 6–4, 6–4 against Mariaan de Swardt and Mary Joe Fernández.
The 1999 Family Circle Cup doubles was the doubles event of the twenty-seventh edition of the tennis tournament played at Hilton Head, United States. It is the third WTA Tier I tournament of the year, and part of the US Spring tennis season. Conchita Martínez and Patricia Tarabini were the defending champions but lost in the second round to Silvia Farina and Corina Morariu.
Vera Zvonareva and Bob Bryan were the defending champions, but Zvonareva did not participate in this U.S. Open due to injury. Bryan partnered Rennae Stubbs, and the pair lost in the quarterfinals to Corina Morariu and Mike Bryan.
Julie Halard-Decugis and Ai Sugiyama were the defending champions but did not compete that year.
The 1999 US Open mixed doubles was the mixed doubles event of the hundred-and-ninth edition of the US Open, the fourth and last Grand Slam of the year. Serena Williams and Max Mirnyi were the defending champions but did not compete that year.
Lindsay Davenport and Corina Morariu defeated Mariaan de Swardt and Elena Tatarkova in the final, 6–4, 6–4 to win the ladies' doubles tennis title at the 1999 Wimbledon Championships.
Serena and Venus Williams defeated Chanda Rubin and Sandrine Testud in the final, 4–6, 6–1, 6–4 to win the women's doubles tennis title at the 1999 US Open. It was the second doubles major title for the Williams sisters, and their second step towards completing the career Golden Slam in doubles.
Serena and Venus Williams defeated Lindsay Davenport and Corina Morariu in the final, 6–2, 4–6, 6–4 to win the women's doubles tennis title at the 2001 Australian Open. It was the Williams sisters' fourth major doubles title, and they completed the career Golden Slam in doubles with the win.
The 2001 French Open was the second Grand Slam event of 2001 and the 100th edition of the French Open. It took place at the Stade Roland Garros in Paris, France, from late May through early June, 2001.
Donald Johnson and Kimberly Po-Messerli were the defending champions but lost in the quarterfinals to Leoš Friedl and Daniela Hantuchová.
The mixed doubles of the 2002 Australian Open was held for the 58th time since the first tournament back in 1922. Heading into the tournament, Corina Morariu and Ellis Ferreira were the defending champions, but could not defend their title. While Morariu did not compete this year, Ferreira partnered with Cara Black and lost in the first Round to Rita Grande and Jeff Tarango in three sets.
The 2000 US Open was a tennis tournament played on outdoor hard courts at the USTA National Tennis Center in New York City in New York in the United States. It was the 120th edition of the US Open and was held from 28 August through 10 September 2000.
Katarina Srebotnik and Piet Norval were the defending champions, but lost in second round to Kim Clijsters and Lleyton Hewitt.
Martina Hingis and Anna Kournikova were the defending champions, but competed this year with different partners. Hingis partnered with Mary Pierce and finished the tournament as runners-up, while Kournikova teamed up with Barbara Schett and lost in semifinals to Lisa Raymond and Rennae Stubbs.
Mahesh Bhupathi and Elena Likhovtseva were the defending champions but decided not to play together. Bhupathi played with Paola Suárez and lost in third round to Nenad Zimonjić and Iroda Tulyaganova, while Likhovtseva competed with Bob Bryan and lost in second round to Andy Ram and Anastasia Rodionova.
Arantxa Sánchez Vicario and Jared Palmer were the defending champions, but lost in the quarterfinals to Ai Sugiyama and Ellis Ferreira.
Corina Morariu 
Ellis Ferreira 
Barbara Schett 
Joshua Eagle 
