Virginia Ruano Pascual and Paola Suárez were the two-time defending champions, but they were defeated in the second round by Anna Chakvetadze and Elena Vesnina.
Cara Black and Liezel Huber were the defending champions, but did not play together. Black partnered with Rennae Stubbs and Huber partnered with Martina Navratilova but both pairs lost to Yan Zi and Zheng Jie, in the semifinals and quarterfinals respectively.
Yan Zi and Zheng Jie were the defending champions but Zheng did not compete. Yan partnered with Peng Shuai but lost in the quarterfinals to Alicia Molik and Mara Santangelo.
Virginia Ruano Pascual and Paola Suárez were the defending champions, and successfully defended their title, defeating Cara Black and Liezel Huber in the final 4–6, 6–3, 6–3 Cara Black would fail to complete the career grand slam in women's doubles because of this loss
Cara Black and Rennae Stubbs were the defending champions, but did not play together. Stubbs partnered with Lisa Raymond but lost in the first round to Stéphanie Cohen-Aloro and Selima Sfar.
Kim Clijsters and Ai Sugiyama were the defending champions, but Clijsters chose not to participate. Sugiyama played alongside Liezel Huber, but they lost in the first round to Shinobu Asagoe and Rika Fujiwara.
Kimberly Po-Messerli and Nicole Pratt were the defending champions. They were both present but did not compete together.
Po-Messerli partnered with Corina Morariu, but lost in the quarterfinals to Virginia Ruano Pascual and Paola Suárez.
Pratt partnered with Alicia Molik, but withdrew before their second round match against Elena Dementieva and Janette Husárová.
At the 2004 Acura Classic doubles tennis competition, Kim Clijsters and Ai Sugiyama were the defending champions, but Clijsters chose not to participate, and only Sugiyama competed that year. Sugiyama partnered with Shinobu Asagoe, but lost in the first round to Amélie Mauresmo and Mary Pierce.
Serena and Venus Williams were the defending champions, but lost in the third round to Elena Dementieva and Lina Krasnoroutskaya.
Nicole Arendt and Ai Sugiyama were the defending champions but they competed with different partners that year, Arendt with Liezel Huber and Sugiyama with Elena Tatarkova.
Serena and Venus Williams defeated Virginia Ruano Pascual and Paola Suárez in the final, 6–2, 7–5 to win the ladies' doubles tennis title at the 2002 Wimbledon Championships. It was their second Wimbledon doubles title together and sixth major title together overall.
Serena Williams and Venus Williams were the defending champions, but Serena withdrew from the tournament and Venus chose not to participate with another player.
Martina Hingis and Anna Kournikova defeated Daniela Hantuchová and Arantxa Sánchez Vicario 6–2, 6–7(4–7), 6–1 in the final to win the title.
Virginia Ruano Pascual and Paola Suárez were the defending champions and won in the final 6–2, 6–3, against Svetlana Kuznetsova and Martina Navratilova in straight sets. This was Ruano Pascual's 4th career Grand Slam doubles title and her 2nd title at the US Open. It was also Suárez' 4th career Grand Slam doubles title and her 2nd title at the US Open.
Serena and Venus Williams were the defending champions but withdrew in the third round.
Martina Hingis and Mary Pierce were the defending champions, but neither participated in this tournament.
The 2000 US Open was a tennis tournament played on outdoor hard courts at the USTA National Tennis Center in New York City in New York in the United States of America. It was the 120th edition of the US Open and was held from 28 August through 10 September 2000.
Lisa Raymond and Rennae Stubbs were the defending champions, but lost in third round to Kim Clijsters and Meghann Shaughnessy.
Virginia Ruano Pascual and Paola Suárez were the defending champions and successfully defended their title, defeating Lisa Raymond and Rennae Stubbs 6–4, 6–2 in the final.
Lisa Raymond and Rennae Stubbs were the defending champions, but competed this year with different partners. Raymond teamed up with Lindsay Davenport and were eliminated in second round due to a withdrawal, while Stubbs teamed up with Elena Bovina and lost in first round.
Elena Bovina and Justine Henin-Hardenne were the defending champions but none competed this year, as both players decided to priorize the singles competition.
Cara Black 
Rennae Stubbs 
Liezel Huber 
Ai Sugiyama 
