3'-demethylstaurosporine O-methyltransferase

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3'-demethylstaurosporine O-methyltransferase
Identifiers
EC no. 2.1.1.139
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
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In enzymology, a 3'-demethylstaurosporine O-methyltransferase (EC 2.1.1.139) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 3'-demethylstaurosporine S-adenosyl-L-homocysteine + staurosporine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 3'-demethylstaurosporine, whereas its two products are S-adenosylhomocysteine and staurosporine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase. Other names in common use include 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase, and staurosporine synthase.

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References


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