| 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.7.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (EC 1.2.7.7) is an enzyme that catalyzes the chemical reaction
+ coenzyme A + 2 oxidised ferredoxin
CO2 + H+
CO2 + H+
Isobutyryl-CoA
+ 2 reduced ferredoxin
The substrates of this enzyme are α-ketoisovaleric acid, coenzyme A, and oxidized ferredoxin. Its products are isobutyryl-CoA, carbon dioxide, reduced ferredoxin, and a proton. [1] [2] [3] [4]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is '. Other names in common use include 2-ketoisovalerate ferredoxin reductase', 3-methyl-2-oxobutanoate synthase (ferredoxin), VOR, branched-chain ketoacid ferredoxin reductase, branched-chain oxo acid ferredoxin reductase, keto-valine-ferredoxin oxidoreductase, ketoisovalerate ferredoxin reductase, and 2-oxoisovalerate ferredoxin reductase.
