Acetyl-S-ACP:malonate ACP transferase

Last updated
Acetyl-S-ACP:malonate ACP transferase
Identifiers
EC no. 2.3.1.187
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Acetyl-S-ACP:malonate ACP transferase (EC 2.3.1.187, acetyl-S-ACP:malonate ACP-SH transferase, acetyl-S-acyl-carrier protein:malonate acyl-carrier-protein-transferase, MdcA, MadA, ACP transferase, malonate/acetyl-CoA transferase, malonate:ACP transferase, acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase) is an enzyme with systematic name acetyl-(acyl-carrier-protein):malonate S-(acyl-carrier-protein)transferase. [1] [2] [3] [4] [5] This enzyme catalyses the following chemical reaction

acetyl-[acyl-carrier protein] + malonate malonyl-[acyl-carrier protein] + acetate

This is the first step in the catalysis of malonate decarboxylation.

References

  1. ↑ Hilbi H, Dimroth P (1994). "Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase". Archives of Microbiology. 162 (1–2): 48–56. doi:10.1007/bf00264372. PMID   18251085.
  2. ↑ Hoenke S, Schmid M, Dimroth P (June 1997). "Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli". European Journal of Biochemistry. 246 (2): 530–8. doi: 10.1111/j.1432-1033.1997.00530.x . PMID   9208947.
  3. ↑ Koo JH, Kim YS (December 1999). "Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus". European Journal of Biochemistry. 266 (2): 683–90. doi: 10.1046/j.1432-1327.1999.00924.x . PMID   10561613.
  4. ↑ Chohnan S, Akagi K, Takamura Y (January 2003). "Functions of malonate decarboxylase subunits from Pseudomonas putida". Bioscience, Biotechnology, and Biochemistry. 67 (1): 214–7. doi: 10.1271/bbb.67.214 . PMID   12619701.
  5. ↑ Dimroth P, Hilbi H (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology. 25 (1): 3–10. doi: 10.1046/j.1365-2958.1997.4611824.x . PMID   11902724.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.