Alcohol-forming fatty acyl-CoA reductase

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Alcohol-forming fatty acyl-CoA reductase
Identifiers
EC no. 1.2.1.84
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

Alcohol-forming fatty acyl-CoA reductase (EC 1.2.1.84, FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase. [1] This enzyme catalyses the following chemical reaction

a long-chain acyl-CoA + 2 NADPH + 2 H+ a long-chain alcohol + 2 NADP+ + coenzyme A

The enzyme has been characterized from the plant Simmondsia chinensis .

References

  1. Metz JG, Pollard MR, Anderson L, Hayes TR, Lassner MW (March 2000). "Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed". Plant Physiology. 122 (3): 635–44. doi:10.1104/pp.122.3.635. PMC   58898 . PMID   10712526.