Apigenin 4'-O-methyltransferase

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apigenin 4'-O-methyltransferase
Identifiers
EC no. 2.1.1.75
CAS no. 118251-36-8
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In enzymology, an apigenin 4'-O-methyltransferase (EC 2.1.1.75) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,7,4'-trihydroxyflavone (apigenin), whereas its two products are S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone (acacetin).

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Other names in common use include flavonoid O-methyltransferase, and flavonoid methyltransferase. This enzyme participates in flavonoid biosynthesis.

Related Research Articles

<span class="mw-page-title-main">Apigenin</span> Chemical compound

Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool.

<span class="mw-page-title-main">Flavones</span> Class of flavonoid chemical compounds

Flavones are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one).

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Caffeate <i>O</i>-methyltransferase Enzyme

In enzymology, a caffeate O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol 4-methyltransferase is an enzyme that catalyzes the chemical reaction

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The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups. O-methylation has an effect on the solubility of flavonoids.

<span class="mw-page-title-main">Acacetin</span> Chemical compound

Acacetin is a 4′-O-methylated flavone of the parent compound apigenin, found in Robinia pseudoacacia, Turnera diffusa (damiana), Betula pendula, and in the fern Asplenium normale.

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2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl β-D-glucopyranoside 7-O-methyltransferase. This enzyme catalyses the following chemical reaction

References