Gliotoxin is a sulfur-containing mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by several species of fungi, especially those of marine origin. It is the most prominent member of the epipolythiopiperazines, a large class of natural products featuring a diketopiperazine with di- or polysulfide linkage. These highly bioactive compounds have been the subject of numerous studies aimed at new therapeutics. Gliotoxin was originally isolated from Gliocladium fimbriatum, and was named accordingly. It is an epipolythiodioxopiperazine metabolite that is one of the most abundantly produced metabolites in human invasive Aspergillosis (IA).
Aspergillus caespitosus is a species of fungus in the genus Aspergillus. It was described scientifically in 1944 by Kenneth B. Raper and Charles Thom, who isolated it from soil. It is from the Nidulantes section.
Pneumocandin B0, also known as pneumocandin B0, pneumocandin B(0), and hydroxy echinocandin, is an organic chemical compound with the formula C50H80N8O17, produced by the fungus Glarea lozoyensis.
Aspergillus qinqixianii is a species of fungus in the genus Aspergillus which has been isolated from desert soil from the Taklimakan desert in China. It is from the Nidulantes section. Aspergillus qinqixianii produces asteltoxin, asperthecin, emericellin, 2-ω-hydroxyemodin, shamixanthones, terrein, curvularin and dehydrocurvularin.
Aspergillus navahoensis is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1982. It was isolated from sand in Arizona, United States. It has been reported to produce averufin, norsolorinic acid, 6,7,8-trihydroxy-3-methylisocoumarin, desferritriacetylfusigen, echinocandin B, and sterigmatocystin.
Aspergillus quadrilineatus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1939. It has been isolated from soil in New Jersey, Egypt, Spain, China, and Namibia. It has been reported to produce asperthecin, averufin, 7-methoxyaverufin, sterigmatocystin, versicolourin, desferritriacetylfusigen, echinocandin B & E, variacoxanthone B, emestrin, aurantioemestrin, dethiosecoemestrin, emindol DA, microperfuranone, penicillin G, quadrilineatin, and sterigmatocystin.
Aspergillus falconensis is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1989. It has been reported to produce 3,30-Dihydroxy-5,50-dimethyldiphenyl ether, falconensin A-N, falconenson A-B, hopane-6α,7β,22-triol, hopane-7β,22-diol, mitorubrin, monomethyldihydromitorubrin, monomethylmitorubrin, and zeorin.
Aspergillus implicatus is a species of fungus in the genus Aspergillus. It is from the Sparsi section. The species was first described in 1994. It has been reported to produce a versicolorin derivative.
Aspergillus spinulosporus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. It was first described in 2016. It has been reported to produce asperthecin, echinocandin B1, desferritriacetylfusigen, and sterigmatocystin.
Aspergillus asperescens is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1954. It has been isolated from soil from a cave in England.
Aspergillus cleistominutus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. It has been reported to produce arugosin A, arugosin B, arugosin C, asperthecin, aspertetronin A, aspertetronin B, echinocandin B, echinocandin C, echinocandin D, epishamixanthone, shamixanthone, orsellinaldehyde, penicillin G, ruguloxanthone, and sterigmatocystin. It has been isolated from soil in New Jersey, United States.
Aspergillus latus is a species of fungus in the genus Aspergillus in the Nidulantes section.
Aspergillus microthecius is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1985. It has been reported to produce asperthecin, averufin, 7-methoxyaverufin, sterigmatocystin, versicolourin, desferritriacetylfusigen, echinocandin B, echinocandin E, emericellin, emestrin, aurantioemestrin, dethiosecoemestrin Emindol DA, microperfuranone, penicillin G, quadrilineatin, and sterigmatocystin.
Aspergillus pachycristatus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 2012. It has been isolated from soil in Xinjiang in China. It has been reported to produce echinocandins.
Aspergillus purpureus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1975. It has been isolated from soil in Egypt. It has been reported to produce emindol SA, emindol SB, emindol SC, epurpurin A-C, sterigmatocystin, variecolactone, variecolin, and variecolol.
Aspergillus stellatus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1934. It has been isolated from soil in Panama and seeds in India. It has been reported in human infections. It has been reported to produce aflatoxin B1, ajamxanthone, shamixanthone, tajixanthone, tajixanthone hydrate, tajixanthone methanoate, 19-O-methyl-22- methoxypre-shamixanthone, pre-shamixanthone, 15- acetyltajixanthone hydrate, andibenin A, andibenin B, andibenin C, andelesin A, andelesin B, anditomin, arugosin A, arugosin B, arugosin D, asperthecin, astellatol, asteltoxin, desferritriacetylfusigen, dihydroterrein, emervaridione, varioxiranediol, epiisoshamixanthone, ophiobolin C, ophiobolin G, ophiobolin H, ophiobolin K, evariquinone, 2-Furanoic acid, islandicin, isoemericellin, kojic acid, 2-Methoxy-6-(3,4-dihydroxy-hepta-1,5-dienyl)benzyl alcohol, najamxanthone, radixanthone, shahenxanthone, penicillin G, shimalactone A, siderin, stellatic acid, stellatin, stromemycin, terrein, variecoacetal A, variecoacetal B, variecolactone, variecolin, varioxirane, varixanthone, varitriol, and varioxranol A-G.
Aspergillus striatulus is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 1985. It has been isolated from mangrove mud in the Kagh Islands. It has been reported to produce asperthecin, aurantioemestrin, cycloisoemericellin, desferritriacetylfusigen, dithiosilvatin, emindol SA, emindol SB, 7-Hydroxyemodin, paxillin, 1-O-acetylpaxillin, penicillin G, sterigmatocystin, violaceic acid, violaceol I, and violaceol II.
Aspergillus sparsus is a species of fungus in the genus Aspergillus. It is from the Sparsi section. The species was first described in 1944. It has been isolated from soil in Costa Rica and the United States.
Orsellinaldehyde is a dihydroxybenzaldehyde with a methyl side group. It can be classified as a resorcinol, benzaldehyde or toluene derivative. It is a natural product of several fungi. Fungi that contain it include Grifola frondosa, Aspergillus cleistominutus, Aspergillus nidulans, and Agrocybe praecox.
Anditomin is an oxygenated meroterpenoid produced by Aspergillus stellatus or Aspergillus variecolor.
