Caffeoyl-CoA O-methyltransferase

Last updated
caffeoyl-CoA O-methyltransferase
Identifiers
EC no. 2.1.1.104
CAS no. 120433-42-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a caffeoyl-CoA O-methyltransferase (EC 2.1.1.104) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + caffeoyl-CoA S-adenosyl-L-homocysteine + feruloyl-CoA

Thus, the two substrates of this enzyme are S-adenosyl methionine and caffeoyl-CoA, whereas its two products are S-adenosylhomocysteine and feruloyl-CoA. A large number of natural products are generated via a step involving this enzyme. [1]

This enzyme is classified to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase. Other names in common use include caffeoyl coenzyme A methyltransferase, caffeoyl-CoA 3-O-methyltransferase, and trans-caffeoyl-CoA 3-O-methyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1SUI and 1SUS.

Related Research Articles

In enzymology, a 3-demethylubiquinone-9 3-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a caffeate O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a columbamine O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a demethylmacrocin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a hexaprenyldihydroxybenzoate methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol 1-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an inositol 3-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an isoflavone 4'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an isoflavone 7-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a licodione 2'-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a loganate O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a luteolin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a macrocin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an O-demethylpuromycin O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a quercetin 3-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a (S)-scoulerine 9-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a tabersonine 16-O-methyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a tetrahydrocolumbamine 2-O-methyltransferase is an enzyme that catalyzes the chemical reaction

References

  1. Wout Boerjan, John Ralph, Marie Baucher "Lignin Biosynthesis" Annu. Rev. Plant Biol. 2003, vol. 54, pp. 519–46. doi : 10.1146/annurev.arplant.54.031902.134938