Carbamoyl aspartic acid

Last updated
Carbamoyl aspartic acid
N-Carbamoyl-DL-aspartic acid.svg
Names
IUPAC name
2-(Carbamoylamino)butanedioic acid [1]
Identifiers
3D model (JSmol)
3DMet
1726861, 1726860 S
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.011.906
EC Number
  • 213-096-6
KEGG
MeSH ureidosuccinic+acid
PubChem CID
UNII
Properties
C5H8N2O5
Molar mass 176.128 g·mol−1
log P −0.663
Acidity (pKa)3.649
Basicity (pKb)10.348
Related compounds
Related alkanoic acids
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Carbamoyl aspartic acid (or ureidosuccinic acid) is a carbamate derivative which serves as an intermediate in pyrimidine biosynthesis.

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Chlorine Chemical element with atomic number 17

Chlorine is a chemical element with the symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate between them. Chlorine is a yellow-green gas at room temperature. It is an extremely reactive element and a strong oxidising agent: among the elements, it has the highest electron affinity and the third-highest electronegativity on the Pauling scale, behind only oxygen and fluorine.

Carboxylic acid Oxoacid having the structure RC(=O)OH, used as a suffix in systematic name formation to denote the –C(=O)OH group including its carbon atom

A carboxylic acid is an organic compound that contains a carboxyl group attached to an R-group. The general formula of a carboxylic acid is R–COOH, with R referring to the alkyl group. Carboxylic acids occur widely. Important examples include the amino acids and fatty acids. Deprotonation of a carboxylic acid gives a carboxylate anion.

Hydroxy group Chemical group

A hydroxy or hydroxyl group is the entity with the formula OH. It contains oxygen bonded to hydrogen. In organic chemistry, alcohols and carboxylic acids contain hydroxy groups. Both the negatively charged anion OH, called hydroxide, and the neutral radical ·OH, known as the hydroxyl radical, consist of an unbounded hydroxyl group.

Ketone Class of organic compounds having structure RCOR´

In chemistry, a ketone is a functional group with the structure RC(=O)R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group (a carbon-oxygen double bond). The simplest ketone is acetone (R = R' = methyl), with the formula CH3C(O)CH3. Many ketones are of great importance in industry and in biology. Examples include many sugars (ketoses), many steroids (e.g., testosterone), and the solvent acetone.

Nitrogen Chemical element with atomic number 7

Nitrogen is the chemical element with the symbol N and atomic number 7. It was first discovered and isolated by Scottish physician Daniel Rutherford in 1772. Although Carl Wilhelm Scheele and Henry Cavendish had independently done so at about the same time, Rutherford is generally accorded the credit because his work was published first. The name nitrogène was suggested by French chemist Jean-Antoine-Claude Chaptal in 1790 when it was found that nitrogen was present in nitric acid and nitrates. Antoine Lavoisier suggested instead the name azote, from the Greek ἀζωτικός "no life", as it is an asphyxiant gas; this name is instead used in many languages, such as French, Russian, Romanian and Turkish, and appears in the English names of some nitrogen compounds such as hydrazine, azides and azo compounds.

Nitric acid (HNO3), also known as aqua fortis (Latin for "strong water") and spirit of niter, is a highly corrosive mineral acid.

Organic compound Chemical compound that contains carbon (except for several compounds traditionally classified as inorganic compounds)

In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen bonds. Due to carbon's ability to catenate, millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprises the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds, along with a handful of other exceptions, are not classified as organic compounds and are considered inorganic. Other than those just named, little consensus exists among chemists on precisely which carbon-containing compounds are excluded, making any rigorous definition of an organic compound elusive.

Peroxide any chemical compound containing an oxygen–oxygen single bond

Peroxides are a group of compounds with the structure R−O−O−R. The O−O group in a peroxide is called the peroxide group or peroxo group. In contrast to oxide ions, the oxygen atoms in the peroxide ion have an oxidation state of −1.

Sulfur Chemical element with atomic number 16

Sulfur (in British English, sulphur) is a chemical element with the symbol S and atomic number 16. It is abundant, multivalent, and nonmetallic. Under normal conditions, sulfur atoms form cyclic octatomic molecules with a chemical formula S8. Elemental sulfur is a bright yellow, crystalline solid at room temperature.

Salt (chemistry) Ionic compound consisting of cations and anions

In chemistry, a salt is a chemical compound consisting of an ionic assembly of cations and anions. Salts are composed of related numbers of cations and anions so that the product is electrically neutral. These component ions can be inorganic, such as chloride (Cl), or organic, such as acetate ; and can be monatomic, such as fluoride (F) or polyatomic, such as sulfate.

Aldehyde Organic compound containing a functional group with the structure −CHO

An aldehyde is a compound containing a functional group with the structure −CHO, consisting of a carbonyl center with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain. The group—without R—is the aldehyde group, also known as the formyl group. Aldehydes are common in organic chemistry, and many fragrances are or contain aldehydes.

A conjugate acid, within the Brønsted–Lowry acid–base theory, is a chemical compound formed by the reception of a proton (H+) by a base—in other words, it is a base with a hydrogen ion added to it, as in the reverse reaction it loses a hydrogen ion. On the other hand, a conjugate base is what is left over after an acid has donated a proton during a chemical reaction. Hence, a conjugate base is a species formed by the removal of a proton from an acid, as in the reverse reaction it is able to gain a hydrogen ion. Because some acids are capable of releasing multiple protons, the conjugate base of an acid may itself be acidic.

Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH3COCOO, is a key intermediate in several metabolic pathways throughout the cell.

Carbonyl group functional group

In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C=O. It is common to several classes of organic compounds, as part of many larger functional groups. A compound containing a carbonyl group is often referred to as a carbonyl compound.

Oxidizing agent Chemical compound used to oxidize another substance in a chemical reaction

In chemistry, an oxidizing agent is a substance that has the ability to oxidize other substances — in other words to accept their electrons. Common oxidizing agents are oxygen, hydrogen peroxide and the halogens.

Phosphoric acid Chemical compound

Phosphoric acid, also known as orthophosphoric acid or phosphoric(V) acid, is a weak acid with the chemical formula H
3
PO
4
. It is normally encountered as a colorless syrup of 85% concentration in water. The pure compound is a colorless solid.

An oxyacid, oxoacid, or ternary acid is an acid that contains oxygen. Specifically, it is a compound that contains hydrogen, oxygen, and at least one other element, with at least one hydrogen atom bond to oxygen that can dissociate to produce the H+ cation and the anion of the acid.

Hydrogen fluoride chemical compound

Hydrogen fluoride is a chemical compound with the chemical formula HF. This colorless gas or liquid is the principal industrial source of fluorine, often as an aqueous solution called hydrofluoric acid. It is an important feedstock in the preparation of many important compounds including pharmaceuticals and polymers. HF is widely used in the petrochemical industry as a component of superacids. Hydrogen fluoride boils near room temperature, much higher than other hydrogen halides.

Dihydroorotase class of enzymes

Dihydroorotase is an enzyme which converts carbamoyl aspartic acid into 4,5-dihydroorotic acid in the biosynthesis of pyrimidines. It forms a multifunctional enzyme with carbamoyl phosphate synthetase and aspartate transcarboymalase.

In chemical nomenclature, a preferred IUPAC name (PIN) is a unique name, assigned to a chemical substance and preferred among the possible names generated by IUPAC nomenclature. The "preferred IUPAC nomenclature" provides a set of rules for choosing between multiple possibilities in situations where it is important to decide on a unique name. It is intended for use in legal and regulatory situations.

References

  1. "ureidosuccinic acid - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification. Retrieved 27 June 2012.