Catherine E. Costello

Last updated
Catherine E. Costello
Alma mater Georgetown University
Scientific career
Institutions Boston University School of Medicine
Thesis Electrophilic brominations of poly-substituted olefins; reactions and NMR studies  (1971)

Catherine E. Costello is the William Fairfield Warren distinguished professor in the department of biochemistry, Cell Biology and Genomics, and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine. [1]

Contents

Education

Catherine E. Costello attended the Emmanuel College in Boston for her undergraduate studies in chemistry, and minors in mathematics and physics. [2] She received a Master of Science (1967) and a PhD from Georgetown University (1971). [3] [4] After graduation, she did post-doctoral research with Klaus Biemann at Massachusetts Institute of Technology.

Career

Prior to founding the Center for Biomedical Mass Spectrometry at Boston University School of Medicine in 1994, Costello was a senior research scientist and the associate director of the National Institutes of Health Research Resource for Mass Spectrometry at Massachusetts Institute of Technology for 20 years. [5] [6] She is a William Fairfield Warren Distinguished Professor and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine. [5] [7]

Costello served as the president of the American Society for Mass Spectrometry (2002–2004), [8] the Human Proteome Organization (2011–2012), [9] and the International Mass Spectrometry Foundation (2014–2018). [10] She currently serves on the board of directors of the US Human Proteome Organization, [11] and the editorial board of Clinical Proteomics. [12]

Research

Her research involves structural characterization of biopolymers using mass spectrometry-based techniques, such as liquid chromatography-mass spectrometry, thin-layer chromatography-mass spectrometry, Fourier-transform ion cyclotron resonance mass spectrometry, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, microfluidic capillary electrophoresis-mass spectrometry, and ion mobility spectrometry-mass spectrometry. [7] [13] She was one of the first scientists to characterize glycoconjugates with tandem mass spectrometry. [6] Her 1988 article has been cited over two thousand times. [14] She participated in the Human Proteome Project, [15] the SysteMHC Atlas project, [16] and the Minimum Information Required for a Glycomics Experiment (MIRAGE) project. [17]

Awards

Awards in her honor

Related Research Articles

Defined in the narrowest sense, glycobiology is the study of the structure, biosynthesis, and biology of saccharides that are widely distributed in nature. Sugars or saccharides are essential components of all living things and aspects of the various roles they play in biology are researched in various medical, biochemical and biotechnological fields.

<span class="mw-page-title-main">Ruedi Aebersold</span> Swiss biologist (born 1954)

Rudolf Aebersold is a Swiss biologist, regarded as a pioneer in the fields of proteomics and systems biology. He has primarily researched techniques for measuring proteins in complex samples, in many cases via mass spectrometry. Ruedi Aebersold is a professor of Systems biology at the Institute of Molecular Systems Biology (IMSB) in ETH Zurich. He was one of the founders of the Institute for Systems Biology in Seattle, Washington, where he previously had a research group.

The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes the development and awareness of proteomics research, advocates on behalf of proteomics researchers throughout the world, and facilitates scientific collaborations between members and initiatives. Ultimately, it is organized to gain a better and more complete understanding of the human proteome.

<span class="mw-page-title-main">American Society for Biochemistry and Molecular Biology</span> Organization founded in 1906

The American Society for Biochemistry and Molecular Biology (ASBMB) is a learned society that was founded on December 26, 1906, at a meeting organized by John Jacob Abel. The roots of the society were in the American Physiological Society, which had been formed some 20 years earlier. ASBMB is the US member of the International Union of Biochemistry and Molecular Biology.

The Proteomics Standards Initiative (PSI) is a working group of the Human Proteome Organization. It aims to define data standards for proteomics to facilitate data comparison, exchange and verification.

Joshua Coon is a professor of chemistry and biomolecular chemistry and the inaugural holder of the Thomas and Margaret Pyle Chair at the University of Wisconsin–Madison, and an affiliate of the Morgridge Institute for Research.

<span class="mw-page-title-main">Catherine Clarke Fenselau</span> American scientist

Catherine Clarke Fenselau is an American scientist who was the first trained mass spectrometrist on the faculty of an American medical school; she joined Johns Hopkins School of Medicine in 1968. She specializes in biomedical applications of mass spectrometry. She has been recognized as an outstanding scientist in the field of bioanalytical chemistry because of her work using mass spectrometry to study biomolecules.

<span class="mw-page-title-main">Milos Novotny</span> American chemist (born 1942)

Milos Vratislav Novotny is an American chemist, currently the Distinguished Professor Emeritus and Director of the Novotny Glycoscience Laboratory and the Institute for Pheromone Research at Indiana University, and also a published author. Milos Novotny received his Bachelor of Science from the University of Brno, Czechoslovakia in 1962. In 1965, Novotny received his Ph.D. at the University of Brno. Novotny also holds honorary doctorates from Uppsala University, Masaryk University and Charles University, and he has been a major figure in analytical separation methods. Novotny was recognized for the development of PAGE Polyacrylamide Gel-filled Capillaries for Capillary Electrophoresis in 1993. In his years of work dedicated to analytical chemistry he has earned a reputation for being especially innovative in the field and has contributed a great deal to several analytical separation methods. Most notably, Milos has worked a great deal with microcolumn separation techniques of liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis. Additionally, he is highly acclaimed for his research in proteomics and glycoanalysis and for identifying the first mammalian pheromones.

Pier Giorgio Righetti is a professor emeritus of chemistry. He worked primarily at the University of Milano (1971-1995) and at the Department of Chemistry of the Politecnico di Milano in Milan, Italy (2005-2011). He has served as the President of the Società Italiana di Proteomica.

Ying Ge is a Chinese-American chemist who is a Professor of Cell and Regenerative Biology at the University of Wisconsin–Madison. Her research considers the molecular mechanisms that underpin cardiac disease. She has previously served on the board of directors of the American Society for Mass Spectrometry. In 2020 Ge was named on the Analytical Scientist Power List.

Olga Vitek is a biostatistician and computer scientist specializing in bioinformatics, proteomics, mass spectrometry, causal inference of biological function, and the development of open-source software for statistical analysis in these areas. She is a professor in the College of Science and Khoury College of Computer Sciences of Northeastern University.

Jennifer Eileen Van Eyk is the Erika Glazer Chair in Women's Heart Health, the Director of Advanced Clinical Biosystems Institute in the Department of Biomedical Sciences, the Director of Basic Science Research in the Women's Heart Center, a Professor in Medicine and in Biomedical Sciences at Cedars-Sinai. She is a renowned scientist in the field of clinical proteomics.

Nicki Packer FRSC is an Australian college professor and researcher. She currently serves as a distinguished professor of glycoproteomics in the School of Natural Sciences at Macquarie University and principal research leader at Griffith University's Institute for Glycomics. Packer is a Fellow of the Royal Society of Chemistry and in 2021 received the Distinguished Achievement in Proteomic Sciences Award from the Human Proteome Organization. Her research focuses on biological functional of glycoconjugates by linking glycomics with proteomics and bioinformatics.

Lingjun Li is a Professor in the School of Pharmacy and Department of Chemistry at University of Wisconsin-Madison. She develops mass spectrometry based tools to study neuropeptides, peptide hormones and neurotransmitters.

Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.

Karin Dorinda Norlin Rodland is an American cancer cell biologist. She is a professor emeritus at Oregon Health and Science University.

Paola Picotti is an Italian biologist who is Professor for Molecular Systems Biology at ETH Zürich. She is Deputy Head of the Institute for Molecular Systems Biology. Her research investigates how the conformational changes of proteins impact cellular networks. She was awarded the 2020 ETH Zürich Rössler Prize and the 2019 EMBO Gold Medal.

Yu-Ju Chen is a Taiwanese proteomics research scientist, who leads international projects in proteogenomics.

Peipei Ping is an academic specializing in cardiac physiology, system biology and data science.

References

  1. ↑ "Boston University Profile".
  2. ↑ Bhattacharya, Nivedita (2018). "Pioneering women in mass spectrometry – an interview with Catherine E. Costello". Rapid Communications in Mass Spectrometry. 32 (8): 607–611. Bibcode:2018RCMS...32..607B. doi: 10.1002/rcm.8078 . ISSN   1097-0231. PMID   29419936.
  3. ↑ "Bromination reactions of selected terpenes and cholesterol". Georgetown University Library. Archived from the original on 2021-11-08. Retrieved 2021-11-08.
  4. ↑ "Electrophilic brominations of poly-substituted olefins; reactions and NMR studies". Georgetown University Library. Archived from the original on 2021-11-08. Retrieved 2021-11-08.
  5. 1 2 "Catherine E. Costello, Director | Mass Spectrometry Resource". www.bumc.bu.edu. Retrieved 2021-11-07.
  6. 1 2 3 "MCP_2020 Award Winner". www.glycobiology.org. Retrieved 2021-11-07.
  7. 1 2 "Catherine E. Costello | Biochemistry". www.bumc.bu.edu. Retrieved 2021-11-07.
  8. ↑ "Past Presidents". www.asms.org. Retrieved 2021-11-07.
  9. ↑ "HUPOST The newsletter of the Human Proteome Organisation" (PDF). Human Proteome Organization. Archived (PDF) from the original on 2020-09-20. Retrieved November 6, 2021.
  10. ↑ "MSACL 2020 US : Costello". www.msacl.org. Retrieved 2021-11-07.
  11. ↑ "US HUPO – Board of Directors". www.ushupo.org. Retrieved 2021-11-07.
  12. ↑ "Clinical Proteomics". Clinical Proteomics. Retrieved 2021-11-07.
  13. ↑ "costello ce – Search Results – PubMed". PubMed. Retrieved 2021-11-08.
  14. ↑ Domon, Bruno; Costello, Catherine E. (1988-12-01). "A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates". Glycoconjugate Journal. 5 (4): 397–409. doi:10.1007/BF01049915. ISSN   1573-4986. S2CID   206787925.
  15. ↑ Legrain, P.; Aebersold, R.; Archakov, A.; Bairoch, A.; Bala, K.; Beretta, L.; Bergeron, J.; Borchers, C.; Corthals, G. L.; Costello, C. E.; Deutsch, E. W. (2011-04-29). "The human proteome project: Current state and future direction". Molecular & Cellular Proteomics: O111.009993. doi: 10.1074/mcp.O111.009993 . ISSN   1535-9476. PMID   21531903.
  16. ↑ Shao, Wenguang; Pedrioli, Patrick G A; Wolski, Witold; Scurtescu, Cristian; Schmid, Emanuel; Vizcaíno, Juan A; Courcelles, Mathieu; Schuster, Heiko; Kowalewski, Daniel; Marino, Fabio; Arlehamn, Cecilia S L (2018-01-04). "The SysteMHC Atlas project". Nucleic Acids Research. 46 (D1): D1237–D1247. doi:10.1093/nar/gkx664. ISSN   0305-1048. PMC   5753376 . PMID   28985418.
  17. ↑ Campbell, Matthew P; Abrahams, Jodie L; Rapp, Erdmann; Struwe, Weston B; Costello, Catherine E; Novotny, Milos; Ranzinger, Rene; York, William S; Kolarich, Daniel; Rudd, Pauline M; Kettner, Carsten (2019-05-01). "The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines". Glycobiology. 29 (5): 349–354. doi:10.1093/glycob/cwz009. ISSN   1460-2423. PMID   30778580.
  18. ↑ "The Power List 2023". The Analytical Scientist. 2023-09-10. Retrieved 2023-09-02.
  19. ↑ "Society for Glycobiology Awards—2020". Glycobiology. 30 (12): 936–940. 2020-12-09. doi:10.1093/glycob/cwaa088. ISSN   1460-2423. PMID   33080621.
  20. ↑ "Glycobiology society honors; NAI inducts Batzer; inspiring Latinx scientists". www.asbmb.org. Retrieved 2021-11-07.
  21. ↑ "BU's Catherine Costello receives Lifetime Achievement in Proteomics Award". EurekAlert!. Retrieved 2021-11-07.
  22. 1 2 "US HUPO – Lifetime Achievement Award". www.ushupo.org. Retrieved 2021-11-07.
  23. ↑ "Catherine Costello Receives Lifetime Achievement in Proteomics Award | School of Medicine". www.bumc.bu.edu. Retrieved 2021-11-07.
  24. ↑ "BU's Catherine Costello receives Lifetime Achievement in Proteomics Award". SCIENMAG: Latest Science and Health News. 2019-03-11. Retrieved 2021-11-07.
  25. ↑ "Catherine Costello". The Analytical Scientist. Retrieved 2021-11-07.
  26. ↑ "John B. Fenn Distinguished Contribution". www.asms.org. Retrieved 2021-11-07.
  27. ↑ Zaia, Joseph; Bierbaum, Veronica M. (2018-06-01). "Focus on Mass Spectrometry in Glycobiology and Related Fields, Honoring Catherine E. Costello, Recipient of the 2017 ASMS Award for a Distinguished Contribution in Mass Spectrometry". Journal of the American Society for Mass Spectrometry. 29 (6): 1061–1064. Bibcode:2018JASMS..29.1061Z. doi: 10.1007/s13361-018-1957-3 . ISSN   1879-1123. PMID   29855889. S2CID   46920892.
  28. ↑ "2016 Fellows | American Association for the Advancement of Science". www.aaas.org. Retrieved 2021-11-07.
  29. 1 2 "HUPO – Past Award Recipients". www.hupo.org. Retrieved 2021-11-07.
  30. ↑ Ludwig-Gross, Michaela. "Wolfgang-Paul-Lecture". DGMS (in German). Retrieved 2022-12-27.
  31. ↑ "William Fairfield Warren Distinguished Professorship | Office of the Provost". www.bu.edu. Retrieved 2021-11-07.
  32. ↑ "2011 ACS Fellows". American Chemical Society. Retrieved 2021-11-07.
  33. ↑ "Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry". American Chemical Society. Retrieved 2021-11-07.
  34. ↑ "Thomson Medal Award | IMSC 2021" (in Brazilian Portuguese). 2019-08-30. Retrieved 2021-11-07.
  35. ↑ "Catherine E. Costello Award". Females in Mass Spectrometry. 2020-07-12. Retrieved 2021-11-07.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.