Columbamine O-methyltransferase

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columbamine O-methyltransferase
Identifiers
EC no. 2.1.1.118
CAS no. 105843-76-3
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In enzymology, a columbamine O-methyltransferase (EC 2.1.1.118) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + columbamine S-adenosyl-L-homocysteine + palmatine

Thus, the two substrates of this enzyme are S-adenosyl methionine and columbamine, whereas its two products are S-adenosylhomocysteine and palmatine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:columbamine O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

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References


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