Elapegademase

Last updated
Elapegademase
Clinical data
Trade names Revcovi
Other nameselapegademase-lvlr
AHFS/Drugs.com Monograph
License data
Routes of
administration
Intramuscular
ATC code
Legal status
Legal status
Identifiers
CAS Number
  • 1709806-75-6
DrugBank
UNII
KEGG

Elapegademase, sold under the brand name Revcovi, is a medication for the treatment of the rare disease adenosine deaminase deficiency-SCID in children and adults.

It is a recombinant enzyme [1] that is administered weekly by intramuscular injection. [2]

Elapegademase may interact with PEGylated drugs. [2]

Elapegademase-lvlr was approved by the U.S. Food and Drug Administration (FDA) in 2018. [3] [4] [5] Leadiant Biosciences was awarded a priority review voucher for its development under the pediatric rare diseases program. [6]

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References

  1. "Elapegademase: Drug Information" . www.uptodate.com. Retrieved 28 March 2019.
  2. 1 2 "LexiComp: Elapegademase-lvlr" . LexiComp. Retrieved 28 March 2019.
  3. "Drug Approval Package: Revcovi". U.S. Food and Drug Administration (FDA). 7 November 2018. Retrieved 26 December 2019.
  4. "Elapegademase-lvlr Orphan Drug Designation and Approval". U.S. Food and Drug Administration (FDA). 24 December 1999. Retrieved 26 December 2019.
  5. "Drug Trial Snapshot: Revcovi". U.S. Food and Drug Administration (FDA). 5 October 2018. Retrieved 26 December 2019.
  6. "Elapegademase - Leadiant Biosciences" . AdisInsight. Springer Nature Switzerland AG. Retrieved 28 March 2019.