Elephantopus scaber

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Elephantopus scaber
Elephantopus scaber in Narshapur forest, AP W2 IMG 0829.jpg
Elephantopus scaber in India
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Asterales
Family: Asteraceae
Genus: Elephantopus
Species:
E. scaber
Binomial name
Elephantopus scaber
L.
Synonyms [1]
  • Elephantopus carolinensisG.Mey.
  • Elephantopus sordidusSalisb.
  • Scabiosa cochinchinensisLour.
  • Elephantopus plurisetus(O.Hoffm.) Clonts, syn of subsp. plurisetus
  • Elephantopus sinuatusZoll. & Moritzi, syn of var. sinuatus
  • Asterocephalus cochinchinensisSprengel

Elephantopus scaber is a tropical species of flowering plant in the family Asteraceae. It is native to tropical Africa, Eastern Asia, Indian Subcontinent, Southeast Asia, and northern Australia. It has become naturalized in tropical Africa and Latin America. Its natural habitat is subtropical or tropical moist montane forests. [2] [3] [4] [5] [6] [7] [8]

Contents

Uses

Elephantopus scaber is used as a traditional medicine. [9] Different parts of the plant are used in traditional medicine of India as an astringent agent, cardiac tonic, and diuretic, and is used for eczema, rheumatism, fever, and bladder stones. [10] E. scaber modulates inflammatory responses by inhibiting the production of TNFα and IL-1β. [11]

Chemical constituents

Elephantopus scaber contains elephantopin which is a germacranolide sesquiterpene lactone containing two lactone rings and an epoxide functional group. [12] [13] 17,19-Dihydrodeoxyelephantopin, iso-17,19- dihydro-deoxy elephantopin and 8-hydroxyl naringenin are the most important bioactive compounds responsible for anti-bacterial activity.[ citation needed ] By UPLC MS Q-TOF, 34 components were identified. [11]

Subspecies and varieties

Varieties of E. scaber include: [1]

References

  1. 1 2 The Plant List, Elephantopus scaber L.
  2. ↑ Flora of China, 地胆草 di dan cao Elephantopus scaber Linnaeus, Sp. Pl. 2: 814. 1753.
  3. ↑ "Atlas of Living Australia, Elephantopus scaber L." Archived from the original on 2015-06-20. Retrieved 2015-06-20.
  4. ↑ Breedlove, D.E. 1986. Flora de Chiapas. Listados Florísticos de México 4: i–v, 1–246.
  5. ↑ Humbert, H. 1960. Composées. Fl. Madagasc. 189: 198-199 description in French
  6. ↑ Humbert, H. 1960. Composées. Fl. Madagasc. 189: plate I (1), figures 10-12 at right line drawings of Elephantopus scaber
  7. ↑ Jeffrey, C. 1988. Notes on Compositae: V. The Vernonieae in East Tropical Africa. Kew Bulletin 43(2): 195–277.
  8. ↑ Nelson, C. H. 2008. Catálogo de las Plantas Vasculares de Honduras 1–1576. Secretaria de Recursos Naturales y Ambiente, Tegucigalpa.
  9. ↑ Poli, A; Nicolau, M; Simoes, Cm; Nicolau, Rm; Zanin, M (Aug 1992). "Preliminary pharmacologic evaluation of crude whole plant extracts of Elephantopus scaber. Part I: in vivo studies". Journal of Ethnopharmacology. 37 (1): 71–6. doi:10.1016/0378-8741(92)90005-C. ISSN   0378-8741. PMID   1453704.
  10. ↑ Wang, Limei; Waltenberger, Birgit; Pferschy-Wenzig, Eva-Maria; Blunder, Martina; Liu, Xin; Malainer, Clemens; Blazevic, Tina; Schwaiger, Stefan; Rollinger, Judith M.; Heiss, Elke H.; Schuster, Daniela; Kopp, Brigitte; Bauer, Rudolf; Stuppner, Hermann; Dirsch, Verena M.; Atanasov, Atanas G. (2014). "Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A review". Biochemical Pharmacology. 92 (1): 73–89. doi:10.1016/j.bcp.2014.07.018. PMC   4212005 . PMID   25083916.
  11. 1 2 Abhimannue, Anu P.; Mohan, Mohind C.; B, Prakash Kumar (13 February 2016). "Inhibition of Tumor Necrosis Factor-α and Interleukin-1β Production in Lipopolysaccharide-Stimulated Monocytes by Methanolic Extract of Elephantopus scaber Linn and Identification of Bioactive Components". Applied Biochemistry and Biotechnology. 179 (3): 427–443. doi:10.1007/s12010-016-2004-0. PMID   26875087. S2CID   7097943.
  12. ↑ "Antitumor activity of elephantopus scaber linn against dalton's ascitis lymphoma". Indian Journal of Pharmaceutical Sciences. 64 (1): 71–3. Jan–Feb 2002. Archived from the original on 2012-06-30.
  13. ↑ "Elephantopus scaber". Germplasm Resources Information Network . Agricultural Research Service, United States Department of Agriculture . Retrieved 7 May 2011.


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