| Character | First Appearance | Status | Description |
|---|
| Peter Parker | Amazing Fantasy #15
(Aug. 1962) | Graduated | Parker was the high school nerd and the wallflower of the high school. Despite not being popular with the students, he was an honor student there. After attending Empire State University, he was depicted as a teacher for the high school for a while. [5] [16] [17] [23] |
| Eugene "Flash" Thompson | Graduated | Football star and meanest bully of the class. [17] [23] He was Peter Parker's nemesis and would bully him the most among the other social underlings. Flash's bullying would cease and eventually the two would become good friends. He returned to serve as the high school coach. |
| Liz Allan | Graduated | Flash's girlfriend all throughout high school. She was also harsh on Peter, but soon developed a crush on him as well. She never dated Peter, but still admired him. |
| Sally Avril | Deceased [24] | A high school gymnast obsessed with superheroes and became one called Bluebird. She gave up the identity when she realized that super heroics were dangerous. She was killed in a car crash while chasing a fight involving Spider-Man. |
| Seymour O'Reilly | Deceased [25] | Friend of Flash's who bullied Peter. He never grew out of his bullying ways to the point that he was jealous of Peter's marriage to Mary Jane Watson. He was killed by the second Venom. |
| Charles "Charlie" Murphy | The Amazing Spider-Man #17
(Oct. 1964) | Graduated | Peter's ex-friend. Became part of Flash's group. |
| C.J. Vogel | The Amazing Spider-Man Annual #17
(Nov. 1983) | Graduated | A student who loved to tell jokes and looked after Peter. Years later, he was in deep trouble and Spider-Man helped him out. |
| Barry Hapgood | Graduated | A shop class expert who became an electronics engineer. |
| Louie Minelli | Graduated | A talkative insurance salesman who was voted "Most Likely to Succeed." |
| Stanley Stackmeyer | Graduated | Considered himself lower than Peter due to his poor hygiene, but went through a radical change and became a handsome, successful married man. |
| Steven Petty | Web of Spider-Man #35
(Feb. 1988) | Unknown | Son of the creator of the Living Brain. Becomes the super villain Phreak. [26] |
| Jake Dorman | Unknown | Jock who would bully Steven Petty |
| Ronda Kramer | Unknown | Jake Dorman's girlfriend who sympathized with Steven Petty |
| Jenny Carson | Marvel Super Heroes: The Revenge of Kang (January 1990) | Unknown | Briefly dated Flash. |
| Jason Ionello | Untold Tales of Spider-Man #1
(Sept. 1995) | Graduated | Popular student who was close with Sally. He was always pulling pranks on Peter. When Sally died, he became depressed and took his anger out on his friends and blamed Spider-Man for the incident. |
| Brian "Tiny" McKeever | Graduated | Used to bully Peter due to his frustrations at home, but became friends with him afterwards. He moved on and became a security guard. |
| Blake | Webspinners: Tales of Spider-Man #7 (July 1999) | Graduated | Peter's rival for the Empire State University scholarship. |
| Carl King | Spider-Man's Tangled Web #1
(June 2001) | Deceased [27] | Bully to Peter who became a hive of spiders called The Thousand. He is stomped and crushed by a pedestrian. |
| Joey Gastone | The Amazing Spider-Man vol. 2 #30 (June 2001) | Expelled | Student bullied by other students. Starts a fire to get back at his tormentors. |
| Jennifer Hardesty | The Amazing Spider-Man vol. 2 #32 (Aug. 2001) | Enrolled | A homeless student who looks after her drug addicted brother. |
| Jessica Jones | Alias #1 (Nov. 2001) | Graduated | Real name was Jessica Campbell. She was involved in a car accident that killed her family, but gave her powers. She had a crush on Peter, but never told him. Years later they would be teammates and she would marry Luke Cage. |
| Paul Patterson | Marvel Team-Up vol. 3 #1 (Jan. 2005) | Enrolled | A troubled, yet powerful mutant nicknamed Golden Child. He received help from Spider-Man whom he deduced was Peter Parker. |
| Charles "Charlie" Weiderman | The Amazing Spider-Man #515
(Feb. 2005) | Graduated | A friend of Peter who was also bullied. He gets coated in liquid vibranium and becomes a villain. |
| Laurie Lynton | Marvel Knights: Spider-Man #13
(June 2005) | Graduated | An overweight girl who had a crush on Peter. Years later, she lost weight and worked at the Daily Bugle with Peter. |
| Vanna Smith | Friendly Neighborhood Spider-Man #5 (April 2006) | Graduated | Girl who thought Spider-Man was stalking her and puts a restraining order on him. She eventually grows up into a lonely, feeble woman with no friends or family. |
| Amelia Hopkins | She-Hulks #1 (Jan. 2011) | Unknown | A goth who initially disliked Lyra, but befriended her after learning she was She-Hulk. She somberly lied about knowing Lyra's identity to the school. |
| Jake Constantine | Unknown | A young boy that Lyra befriends and potentially falls in love with. During the school dance he was blasted by the Wizard. It was left ambiguous whether he survived or not. |
| Andrew "Andy" Maguire | The Amazing Spider-Man #692
(Oct. 2012) | Enrolled | An average student who gains energy powers and names himself Alpha. Becomes Spider-Man's sidekick briefly. |
| Christine "Chrissy" Chen | Enrolled | Former girlfriend to Andy Maguire. |
| A.J. Patton | Venom vol. 2 #27.1 (Nov. 2012) | Graduated | A student who Flash bullied and break his arm. Years later, he is married to Dan. |
| Cindy Moon | The Amazing Spider-Man vol. 2 #1 (June 2014) | Unfinished | A former hockey player for the school, she attended the field trip along with Peter. After the spider bit him, it bit Cindy's ankle giving her similar powers. Years later she meets Peter and becomes the superhero Silk. [28] |
| Clayton Cole | The Amazing Spider-Man vol. 3 #1.1
(June 2014) | Unknown | An average student who admired Spider-Man and became a super villain named Clash. Had a crush on Polly McKenna. |
| Polly McKenna | The Amazing Spider-Man vol. 3 #1.2
(Aug. 2014) | Unknown | A friendly student who befriends Peter and head of the A.V. Club. She turns on Peter when he steals equipment. [29] |
| Lawson | Unknown | A.V. Club student who befriends and then later turns on Peter. [30] |
| Martin | Unknown | A.V. Club student who befriends and then later turns on Peter. [30] |
| Hector Cervantez | Silk #1 (April 2015) | Graduated | Former boyfriend to Cindy Moon. Years later he gets engaged and becomes the superhero Spectro. |
| Ripley Ryan | Captain Marvel vol. 10 #1 (January 2019) | Graduated | A reporter who is a test subject of Minn-Erva's experiments and later becomes the anti-hero Star. |
| Lacey Fisher | Amazing Spider-Man Annual Vol. 4 #2 (June 2021) | Graduated | A student who bullied Ripley Ryan. Years later, Ripley confronted her when she was going home but Spider-Man interrupted Ripley and allowing Lacey to run home. |
