Formaldehyde dismutase

formaldehyde dismutase
Identifiers
EC no.	1.2.98.1
CAS no.	85204-94-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, formaldehyde dismutase (EC 1.2.98.1) is an enzyme that catalyzes the chemical reaction

2

 

formaldehyde

+ H₂O

 

 

 

 

 

 

 

formic acid

+

 

methanol

This enzyme converts formaldehyde into formic acid and methanol. ^{[1] [2] [3] [4]}

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with other acceptors. The systematic name of this enzyme class is formaldehyde:formaldehyde oxidoreductase. Other names in common use include aldehyde dismutase, and cannizzanase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2DPH.

References

1. Enzyme 1.2.98.1 at KEGG Pathway Database.
2. Kato, Nobuo; Shirakawa, Kamon; Kobayashi, Hisataka; Sakazawa, Chikahiro (1983). "The dismutation of aldehydes by a bacterial enzyme". Agricultural and Biological Chemistry. 47: 39–46. doi:10.1271/bbb1961.47.39.
3. Kato, Nobuo; Yamagami, Tomohide; Shimao, Masayuki; Sakazawa, Chikahiro (1986). "Formaldehyde dismutase, a novel NAD-binding oxidoreductase from Pseudomonas putida F61". European Journal of Biochemistry. 156 (1): 59–64. doi:10.1111/j.1432-1033.1986.tb09548.x. PMID   3514215.
4. Park, H.; Lee, H.; Ro, Y. T.; Kim, Y. M. (2010). "Identification and functional characterization of a gene for the methanol : N,N'-dimethyl-4-nitrosoaniline oxidoreductase from Mycobacterium sp. Strain JC1 (DSM 3803)". Microbiology. 156 (2): 463–471. doi: 10.1099/mic.0.034124-0 . PMID   19875438.