Glutarate-semialdehyde dehydrogenase

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glutarate-semialdehyde dehydrogenase
Identifiers
EC no. 1.2.1.20
CAS no. 9028-99-3
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In enzymology, a glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) is an enzyme that catalyzes the chemical reaction

glutarate semialdehyde + NAD+ + H2O glutarate + NADH + 2 H+

The 3 substrates of this enzyme are glutarate semialdehyde, NAD+, and H2O, whereas its 3 products are glutarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glutarate-semialdehyde:NAD+ oxidoreductase. This enzyme is also called glutarate semialdehyde dehydrogenase. This enzyme participates in lysine degradation.

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References


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