Glyoxylate dehydrogenase (acylating)

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glyoxylate dehydrogenase (acylating)
Identifiers
EC no. 1.2.1.17
CAS no. 9028-96-0
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In enzymology, a glyoxylate dehydrogenase (acylating) (EC 1.2.1.17) is an enzyme that catalyzes the chemical reaction

glyoxylate + CoA + NADP+ oxalyl-CoA + NADPH + H+

The 3 substrates of this enzyme are glyoxylate, CoA, and NADP+, whereas its 3 products are oxalyl-CoA, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glyoxylate:NADP+ oxidoreductase (CoA-oxalylating). This enzyme participates in glyoxylate and dicarboxylate metabolism.

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References


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