Harvard AIDS Initiative

Last updated

Since the late 1980s, the Harvard School of Public Health AIDS Initiative (HAI) has been at the forefront of HIV/AIDS research, education and leadership.

Chaired by noted researcher Max Essex, HAI is currently involved in studies to examine drug resistance in patients taking antiretroviral drugs; vaccine development; prevention of HIV transmission from mother-to-infant in utero, as well as through breast feeding; and cost-effectiveness of treatment programs.

Through the Fogarty International Training Program in AIDS-related Epidemiology, the Harvard AIDS Initiative trains biomedical researchers and health care workers from resource scarce countries. At Harvard, trainees study epidemiology, biostatistics, immunology, molecular biology or behavioral sciences, then return to their home countries to continue their research. Participants have come from Botswana, Senegal, Tanzania, Thailand, India, Kenya, and Mexico.

The KITSO AIDS Training Program in Botswana provides sustainable and standardized training in HIV/AIDS care, developed specifically for Botswana’s health professionals. KITSO is a collaboration of the Botswana Ministry of Health and the Botswana-Harvard AIDS Institute. The name of the program, "Kitso" is from the Setswana word for "knowledge." Setswana is a native language of Botswana.

Originally called the Harvard AIDS Institute, HAI officially changed its name to the Harvard School for Public Health AIDS Initiative in 2004.

Related Research Articles

HIV/AIDS in Africa HIV/AIDS in Africa

HIV/AIDS originated in Africa in the early 20th century and is a major public health concern and cause of death in many African countries. AIDS rates vary dramatically although the majority of cases are concentrated in Southern Africa. Although the continent is home to about 15.2 percent of the world's population, more than two-thirds of the total infected worldwide – some 35 million people – were Africans, of whom 15 million have already died. Sub-Saharan Africa alone accounted for an estimated 69 percent of all people living with HIV and 70 percent of all AIDS deaths in 2011. In the countries of sub-Saharan Africa most affected, AIDS has raised death rates and lowered life expectancy among adults between the ages of 20 and 49 by about twenty years. Furthermore, the life expectancy in many parts of Africa is declining, largely as a result of the HIV/AIDS epidemic with life-expectancy in some countries reaching as low as thirty-nine years.

Tropical medicine Interdisciplinary branch of medicine

Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions.

Presidents Emergency Plan for AIDS Relief United States governmental initiative

The United States President's Emergency Plan For AIDS Relief (PEPFAR) is a United States governmental initiative to address the global HIV/AIDS epidemic and help save the lives of those suffering from the disease. Launched by U.S. President George W. Bush in 2003, as of May 2020, PEPFAR has provided about $90 billion in cumulative funding for HIV/AIDS treatment, prevention, and research since its inception, making it the largest global health program focused on a single disease in history until the COVID-19 pandemic. PEPFAR is implemented by a combination of U.S. government agencies in over 50 countries and overseen by the Global AIDS Coordinator at the U.S. Department of State. As of 2021, PEPFAR has saved over 20 million lives, primarily in Sub-Saharan Africa.

Harvard T.H. Chan School of Public Health Public health institution

The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first graduate training program in population health, which was founded in 1913 and then became the Harvard School of Public Health in 1922.

amfAR

amfAR, the Foundation for AIDS Research, known until 2005 as the American Foundation for AIDS Research, is an international nonprofit organization dedicated to the support of AIDS research, HIV prevention, treatment education, and the advocacy of AIDS-related public policy.

Botswana is experiencing one of the most severe HIV/AIDS epidemics in the world. The national HIV prevalence rate among adults ages 15 to 49 is 24.8 percent, which is the third highest in the world, behind Lesotho and Eswatini. HIV/AIDS threatens the many developmental gains Botswana has achieved since its independence in 1966, including economic growth, political stability, a rise in life expectancy, and the establishment of functioning public educational and health care systems.

Max Essex American virologist (born 1939)

Myron Elmer "Max" Essex is the Mary Woodard Lasker Professor of Health Sciences in the Department of Immunology and Infectious Diseases at Harvard University, Chair of the Harvard T.H. Chan School of Public Health AIDS Initiative (HAI) in the Department of Immunology and Infectious Diseases, and Chair of the Botswana–Harvard AIDS Institute in Gaborone, Botswana. Essex was one of the first to link animal and human retroviruses to immunosuppressive disease, to suspect that a retrovirus was the cause of AIDS, and to determine that HIV could be transmitted through blood and blood products to hemophiliacs and recipients of blood transfusions. With collaborators, Essex also provided the first evidence that HIV could be transmitted by heterosexual intercourse.

HIV/AIDS in Australia

The history of HIV/AIDS in Australia is distinctive, as Australian government bodies recognised and responded to the AIDS pandemic relatively swiftly, with the implementation of effective disease prevention and public health programs, such as needle and syringe programs (NSPs). As a result, despite significant numbers of at-risk group members contracting the virus in the early period following its discovery, the country achieved and has maintained a low rate of HIV infection in comparison to the rest of the world.

Botswana–United States relations Bilateral relations

According to the 2012 U.S. Global Leadership Report, 79% of Botswana people approve of U.S. leadership, with 8% disapproving and 13% uncertain.

NMAC, formerly known as the National Minority AIDS Council, works for health equity and racial justice to end the HIV epidemic in America. The nonprofit organization, located in Washington, D.C., was founded in 1987. NMAC represents over 3,000 community- and faith-based organizations across the US. The agency advances its mission by providing minority and minority-serving faith- and community-based organizations with capacity building assistance programs, online and classroom-based trainings, printed and electronic resources, grassroots organization and political advocacy. These activities improve the delivery of HIV/AIDS services, helping to mitigate the impact of HIV/AIDS in underserved and marginalized communities.

With less than 0.1 percent of the population estimated to be HIV-positive, Bangladesh is a low HIV-prevalence country.

HIV/AIDS in Canada

HIV/AIDS was first detected in Canada in 1982. In 2018, there were approximately 62,050 people living with HIV/AIDS in Canada. It was estimated that 8,300 people were living with undiagnosed HIV in 2018. Mortality has decreased due to medical advances against HIV/AIDS, especially highly active antiretroviral therapy (HAART).

Kamiar and Arash Alaei incident Iranian HIV/AIDS physicians

Dr. Kamiar Alaei and his brother Dr. Arash Alaei are two Iranian HIV/AIDS doctors who were detained in Tehran's Evin prison from June 2008 through Dec 2010 and August 2011, respectively. Prior to their arrest, they developed harm-reduction programs in Iran and developed the program Global Health in the Middle East and Central Asia, an HIV/AIDS training program for regional health experts.

Pride Chigwedere

Pride Chigwedere, a Zimbabwean national, is a Harvard trained physician-scientist working in global health. He is most notable for leading a team of Harvard researchers who demonstrated that South African President Thabo Mbeki's AIDS policies led to more than 300 000 deaths. While South Africa's policies were condemned by many, Chigwedere's contribution was in developing and applying methods to quantify the impact of the policies thus demonstrating the calamitous consequences of AIDS denialism. Generalized, he developed an approach for evaluating public health practice and highlighted the need to develop a framework for accountability in public health. Drawing from the analogy with medicine, he has proposed the concept of public health malpractice to capture negligence that causes harm as a useful first step towards accountability in public health. A response to Chigwedere's work by AIDS denialists led by Peter Duesberg was initially published by the non-peer-reviewed journal Medical Hypotheses followed by a retraction because of poor quality of data, undeclared conflicts of interest, and potential effects on global health.

Botswana's healthcare system has been steadily improving and expanding its infrastructure to become more accessible. The country's position as an upper middle-income country has allowed them to make strides in universal healthcare access for much of Botswana's population. The majority of the Botswana's 2.3 million inhabitants now live within five kilometers of a healthcare facility. As a result, the infant mortality and maternal mortality rates have been on a steady decline. The country's improving healthcare infrastructure has also been reflected in an increase of the average life expectancy from birth, with nearly all births occurring in healthcare facilities.

Wafaa El-Sadr Egyptian physician

Wafaa El-Sadr is a Columbia University Professor and the director of ICAP at Columbia University, Columbia World Projects and the Center for Infectious Disease Epidemiologic Research (CIDER) at Columbia Mailman School of Public Health.

Agnes Binagwaho Rwandan pediatrician

Agnes Binagwaho is a Rwandan pediatrician and currently the vice chancellor of the University of Global Health Equity. In 1996, she moved back to Rwanda where she provided clinical care in the public sector as well as held a number of project management, health system strengthening, and government positions, including Permanent Secretary of the Ministry of Health of Rwanda from October 2008 until May 2011 and Minister of Health from May 2011 until July 2016. She has been a Professor of Global Health Delivery Practice since 2016 and a Professor of Pediatrics since 2017 at the University of Global Health Equity, where she also serves as Vice Chancellor. She currently resides in Kigali.

Martin T. Schechter is a Canadian epidemiologist recognized for contributions to HIV research, prevention and treatments, addiction research, and Indigenous health research. He is a professor and the former founding director of the School of Population and Public Health in the Faculty of Medicine at the University of British Columbia (UBC). Schechter received his Order of British Columbia in 1994 alongside BC's first Nobel Prize laureate Michael Smith and noted Indigenous artist Bill Reid.

Cristina Possas Brazilian public health scientist

Cristina Possas de Albuquerque is a Brazilian public health scientist working with infectious diseases and emerging infectious diseases from an eco-social perspective.

George R. Seage III was an epidemiologist and a professor at the Harvard T.H. Chan School of Public Health and Director of the school's Program in the Epidemiology of Infectious Diseases. Seage specialized in HIV/AIDS research with a focus on “the behavioural and biological aspects of adult and pediatric HIV transmission, natural history and treatment.” At the Boston University School of Public Health (BUSPH), Seage was an Adjunct Associate Professor of Epidemiology in the Department of Epidemiology, Director of the Interdisciplinary Concentration in the Epidemiology of Infectious Diseases, and Director of the Pediatric AIDS Cohort Study (PHACS) data and analysis center.

References