International Classification of Sleep Disorders

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International Classification of Sleep Disorder
Specialty Sleep medicine

The International Classification of Sleep Disorders (ICSD) is "a primary diagnostic, epidemiological and coding resource for clinicians and researchers in the field of sleep and sleep medicine". [1] The ICSD was produced by the American Academy of Sleep Medicine (AASM) in association with the European Sleep Research Society, the Japanese Society of Sleep Research, and the Latin American Sleep Society. The classification was developed as a revision and update of the Diagnostic Classification of Sleep and Arousal Disorders (DCSAD) that was produced by both the Association of Sleep Disorders Centers (ASDC) and the Association for the Psychophysiological Study of Sleep and was published in the journal Sleep in 1979. [2] [3] A second edition, called ICSD-2, was published by the AASM in 2005. [4] The third edition, ICSD-3, was released by the AASM in 2014. [5] A text revision of the third edition (ICSD-3-TR) was published in 2023 by the AASM. [6]

Contents

Milestones of sleep disorder classifications

YearICSDICDDSM
1974DSM-III
1975ICD-9
1979Nosology
1980ICD-CMDSM-III
1987DSM-III-R
1991ICSD
1992ICD-10
1994DSM-IV
1997ICSD-R
2000DSM-IV-TR
2005ICSD-2
2006ICSD-2 Pocket Version
2010ICD-10-CM
2014ICSD-3DSM-5
2015ICD-11 Beta
2022ICD-11
2023ICSD-3-TRDSM-5-TR

Introduction

In 1979, the first Diagnostic Classification of Sleep and Arousal Disorders (DCSAD) was developed by the Association of Sleep Disorders Centers (ASDC) and the Association for the Psychophysiological Study of Sleep. Disorders were divided into four main categories. [2] [3]

  1. Disorders of initiating and maintaining sleep (DIMS) – Insomnias
  2. Disorders of Excessive somnolence (DOES) – Hypersomnias
  3. Disorders of the Sleep-Wake Schedule – Circadian Disorders
  4. Dysfunctions Associated with Sleep, Sleep Stages, or Partial Arousals – Parasomnias

In 1990, the first comprehensive classification of disorders of sleep and arousal, the International Classification of Sleep Disorders (ICSD-1990), was developed by the American Academy of Sleep Medicine (AASM) in association with the European Sleep Research Society, the Japanese Society of Sleep Research, and the Latin American Sleep Society. [7] 84 sleep disorders were inventoried, based on pathophysiological characteristics. It was later revised as the ICSD-R in 1997.

The International Classification of Sleep Disorders (ICSD) uses a multiaxial system for stating and coding diagnoses both in clinical reports or for database purposes. The axial system uses International Classification of Diseases (ICD-9-CM) coding wherever possible. Additional codes are included for procedures and physical signs of particular interest to sleep disorders clinicians and researchers. Diagnoses and procedures are listed and coded on three main "axes". The axial system is arranged as follows: [1]

Axis A ICSD Classification of Sleep Disorders

Axis B ICD-9-CM Classification of Procedures

Axis C ICD-9-CM Classification of Diseases (nonsleep diagnoses).

ICSD-I (1990) and ICSD-Revised (1997)

  1. Dyssomnias
    1. Intrinsic Sleep Disorders
    2. Extrinsic Sleep Disorders
    3. Circadian Rhythm Sleep Disorders
  2. Parasomnias
    1. Arousal Disorders
    2. Sleep-Wake Transition Disorders
    3. Parasomnias Usually Associated with REM Sleep
    4. Other Parasomnias
  3. Sleep Disorders Associated with Mental, Neurologic, or Other Medical Disorders
    1. Associated with Mental Disorders
    2. Associated with Neurologic Disorders
    3. Associated with Other Medical Disorders
  4. Proposed Sleep Disorders
    1. Shorter Sleeper
    2. Long Sleeper
    3. Menstrual-Associated Sleep Disorders

ICSD-2

In 2005, the International Classification of Sleep Disorders underwent minor updates and modifications resulting in version 2 (ICSD-2). [4]

ICSD-2ICD-9-CMICD-10-CM
Insomnia: Insomnia is defined as the subjective perception of difficulty with sleep initiation, duration, consolidation, or quality that occurs despite adequate opportunity for sleep, and that results in some form of daytime impairment. [4]
Adjustment sleep disorder (acute insomnia)307.41F 51.02
Psychophysiological insomnia307.42F 51.04
Paradoxical insomnia (formerly sleep state misperception)307.42F 51.03
Idiopathic insomnia307.42F 51.01
Insomnia due to mental disorder307.42F 51.05
Inadequate sleep hygieneV69.4Z72.821
Behavioral insomnia of childhood307.42
- Sleep-onset association typez73.810
- Limit-setting sleep typez73.811
- Combined typeZ73.812
Insomnia due to drug or substance292.85G47.02
Insomnia due to medical condition (code also the associated medical condition)327.01G47.01
Insomnia not due to a substance or known physiological condition, unspecified780.52F51.09
Physiological (organic) insomnia, unspecified; (organic insomnia, NOS)327.00G47.09
Sleep-Related Breathing Disorders:
Central sleep apnea syndromes
Primary central sleep apnea327.21G47.31
Central sleep apnea due to Cheyne-Stokes breathing pattern768.04R06.3
Central sleep apnea due to high altitude periodic breathing327.22G47.32
Central sleep apnea due to a medical condition, not Cheyne-Stokes327.27G47.31
Central sleep apnea due to a drug or substance327.29F10-19
Primary sleep apnea of infancy770.81P28.3
Obstructive sleep apnea syndromes
Obstructive sleep apnea, adult327.23G47.33
Obstructive sleep apnea, pediatric327.23G47.33
Sleep-related hypoventilation/hypoxemic syndromes
Sleep-related non-obstructive alveolar hypoventilation, bidiopathic327.24G47.34
Congenital central alveolar hypoventilation syndrome327.25G47.35
Sleep-related hypoventilation/hypoxemia due to a medical condition
Sleep-related hypoventilation/hypoxemia due to pulmonary parenchymal or vascular pathology327.26G47.36
Sleep-related hypoventilation/hypoxemia due to lower airways obstruction327.26G47.36
Sleep-related hypoventilation/hypoxemia due to neuromuscular or chest wall disorders327.26G47.36
Other sleep-related breathing disorder
Sleep apnea/sleep related breathing disorder, unspecified320.20G47.30
Hypersomnias of Central Origin:
Narcolepsy with cataplexy347.01G47.411
Narcolepsy without cataplexy347.00G47.419
Narcolepsy due to medical condition347.10G47.421
Narcolepsy, unspecified347.00G47.43
Recurrent hypersomnia780.54G47.13
- Kleine-Levin Syndrome 327.13G47.13
- Menstrual-related hypersomnia327.13G47.13
Idiopathic hypersomnia with long sleep time327.11G47.11
Idiopathic hypersomnia without long sleep time327.12G47.12
Behaviorally induced insufficient sleep syndrome307.44F51.12
Hypersomnia due to medical condition327.14G47.14
Hypersomnia due to drug or substance292.85G47.14
Hypersomnia not due to a substance or known physiological condition327.15F51.1
Physiological (organic) hypersomnia, unspecified (organic hypersomnia, NOS)327.10G47.10
Circadian Rhythm Sleep Disorders:
Circadian rhythm sleep disorder, delayed sleep phase type327.31G47.21
Circadian rhythm sleep disorder, advanced sleep phase type327.32G47.22
Circadian rhythm sleep disorder, irregular sleep-wake type327.33G47.23
Circadian rhythm sleep disorder, free-running (non-entrained) type327.34G47.24
Circadian rhythm sleep disorder, jet lag type327.35G47.25
Circadian rhythm sleep disorder, shift work type327.36G47.26
Circadian rhythm sleep disorders due to medical condition327.37G47.27
Other circadian rhythm sleep disorder327.39G47.29
Other circadian rhythm sleep disorder due to drug or substance292.85G47.27
Parasomnias:
Disorders of arousal (from non-REM sleep)
- Confusional arousals327.41G47.51
- Sleepwalking307.46F51.3
- Sleep terrors307.46F51.4
Parasomnias usually associated with REM sleep
- REM sleep behavior disorder (including parasomnia overlap disorder and status dissociatus)327.42G47.52
- Recurrent isolated sleep paralysis327.43G47.53
- Nightmare disorder307.47F51.5
Other Parasomnias
Sleep-related dissociative disorders300.15F44.9
Sleep enuresis 788.36N39.44
Sleep-related groaning (catathrenia)327.49G47.59
Exploding head syndrome327.49G47.59
Sleep-related hallucinations368.16R29.81
Sleep-related eating disorder327.49G47.59
Parasomnia, unspecified227.40G47.50
Parasomnia due to a drug or substance292.85G47.54
Parasomnia due to a medical condition327.44G47.54
Sleep-Related Movement Disorders:
Restless legs syndrome (including sleep-related growing pains)333.49G25.81
Periodic limb movement sleep disorder 327.51G47.61
Sleep-related leg cramps327.52G47.62
Sleep-related bruxism327.53G47.63
Sleep-related rhythmic movement disorder327.59G47.69
Sleep-related movement disorder, unspecified327.59G47.90
Sleep-related movement disorder due to drug or substance327.59G47.67
Sleep-related movement disorder due to medical condition327.59G47.67
Isolated Symptoms, Apparently Normal Variants, and Unresolved Issues
Long sleeper307.49R29.81
Short sleeper307.49R29.81
Snoring 786.09R06.83
Sleep talking307.49R29.81
Sleep starts, hypnic jerks 307.47R25.8
Benign sleep myoclonus of infancy781.01R25.8
Hypnagogic foot tremor and alternating leg muscle activation during sleep781.01R25.8
Propriospinal myoclonus at sleep onset781.01R25.8
Excessive fragmentary myoclonus 781.01R25.8
Other Sleep Disorders
Other physiological (organic) sleep disorder327.8G47.8
Other sleep disorder not due to a known substance or physiological condition327.8G47.9
Environmental sleep disorder307.48F51.8
Sleep disorders associated with conditions classifiable elsewhere
Fatal familial insomnia046.8A81.8
Fibromyalgia 729.1M79.7
Sleep-related epilepsy 345G40.5
Sleep-related headaches 784.0R51
Sleep-related gastroesophageal reflux disease 530.1K21.9
Sleep-related coronary artery ischemia411.8I25.6
Sleep-related abnormal swallowing, choking, and laryngospasm 787.2R13.1
Other psychiatric/behavioral disorders frequently encountered in the differential diagnosis of sleep disorders
Mood disorders
Anxiety disorders
Somatoform disorders
Schizophrenia and other psychotic disorders
Disorders usually first diagnosed in infancy, childhood, or adolescence
Personality disorders

The ICSD-2 thus lists 81 sleep disorder diagnostic categories divided in 8 major categories. Each diagnostic is detailed in a description that presents the diagnostic criteria. The 81 diagnostics are divided into 8 main categories, namely insomnias, sleep-related breathing disorders, hypersomnias of central origin, circadian rhythm sleep disorders, parasomnias, sleep-related movement disorders, isolated symptoms apparently normal variants and unresolved issues, other sleep disorders. The two last categories (i.e. sleep disorders associated with disorders classified elsewhere and psychiatric disorders frequently encountered in the differential diagnosis of sleep disorders) are presented in the appendices and count 13 diagnostics. [7]

In 2006, a pocket version of the ICSD-2 was released. In this version, a pediatric section was added listing the following diagnostic categories:

  1. Behavioural Insomnia in Childhood
    1. Onset Type
    2. Limit Setting Type
  2. Primary Sleep Apnea of Infancy
  3. Obstructive Sleep Apnea, Pediatric
  4. Congenital Central Alveolar Hypoventilation Syndrome
  5. Sleep Enuresis
  6. Restless Legs Syndrome
  7. Sleep-related Rhythmic Movement Disorder

However, this classification brought some confusion into the field, which led to the revision of the classification in 2011. The classification was much more discussed by experts of the field and led to the third edition of the ICSD.

ICSD-3 (2014) and ICSD-3-TR (2023)

The revision of the ICSD-2 was firstly made by the AASM and other International Societies. This revision integrates pediatric diagnosis into clinical adult diagnosis (except for obstructive sleep apnea) and led to the third edition of the ICSD, which was released in 2014.

ICSD-3 includes specific diagnoses within the seven major categories, as well as an appendix for classification of sleep disorders associated with medical and neurologic disorders. The International Classification of Diseases (ICD-9-CM and ICD-10-CM) codes corresponding to each specific diagnosis can be found within the ICSD-3. [5] Furthermore, pediatric diagnoses are not distinguished from adult diagnoses except for sleep-related breathing disorders. [8]

In addition, significant changes have been made in the nosology of insomnia, narcolepsy and parasomnia. Primary vs. secondary (i.e. comorbid) insomnia has been reunited into a single disorder: chronic insomnia. Narcolepsy has been divided into narcolepsy type 1 and narcolepsy type 2. These two types are distinguished by the presence or absence of cataplexy and the cerebrospinal fluid hypocretin-1 level. Concerning parasomnia, the sections have been modified, grouping together common features. Finally, a section on treatment-emerging CSA has been added to the CSA syndromes section. [8]

It also discusses common isolated symptoms and normal variants. Some occur during normal sleep: as an example, sleep talking occurs at some time in most normal sleepers. Some lie on the continuum between normal and abnormal: as an example, snoring without associated airway compromise, sleep disturbance, or other consequences is essentially normal, whereas heavy snoring is often part of obstructive sleep apnea.

Furthermore, some features are no longer disorders and are reunited in TheAASM [American Academy of Sleep Medicine] Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Therefore, ICSD permanently refers to this manual. The latter allows, for instance, to find definitions of polysomnography or specific features. [8]

The ICSD-3 counts 383 pages for 83 disorders. It is divided into 7 main categories:

1. Insomnia

  1. Chronic insomnia disorder
  2. Short-term insomnia disorder
  3. Other insomnia (when the patient has insomnia symptoms but does not meet criteria for the other two types of insomnia)

Isolated symptoms and normal variants

Obstructive sleep apnea (OSA) syndromes

  1. OSA, adult
  2. OSA, pediatric

Central sleep apnea syndromes

  1. Central sleep apnea with Cheyne-Stokes breathing
  2. Central sleep apnea due a medical disorder without Cheyne-Stokes breathing
  3. Central sleep apnea due to high altitude periodic breathing
  4. Central sleep apnea due to a medication or substance
  5. Primary central sleep apnea
  6. Primary central sleep apnea of infancy
  7. Primary central sleep apnea of prematurity
  8. Treatment-emergent central sleep apnea
  1. Obesity hypoventilation syndrome
  2. Congenital central alveolar hypoventilation syndrome
  3. Late-onset central hypoventilation with hypothalamic dysfunction
  4. Idiopathic central alveolar hypoventilation
  5. Sleep-related hypoventilation due to a medication or substance
  6. Sleep-related hypoventilation due to a medical disorder
Isolated symptoms and normal variants
  1. Snoring
  2. Catathrenia

3. Central disorders of hypersomnolence

  1. Narcolepsy type 1
  2. Narcolepsy type 2
  3. Idiopathic hypersomnia
  4. Kleine-Levin syndrome
  5. Hypersomnia due to a medical disorder
  6. Hypersomnia due to a medication or substance
  7. Hypersomnia associated with a psychiatric disorder
  8. Insufficient sleep syndrome

4. Circadian rhythm sleep-wake disorders

  1. Delayed sleep-wake phase disorder
  2. Advanced sleep-wake phase disorder
  3. Irregular sleep-wake rhythm disorder
  4. Non-24-hour sleep-wake rhythm disorder
  5. Shift work disorder
  6. Jet lag disorder
  7. Circadian sleep-wake disorder not otherwise specified

5. Parasomnias

  1. Confusional arousals
  2. Sleepwalking
  3. Sleep terrors
  4. Sleep-related eating disorder
  1. REM sleep behavior disorder
  2. Recurrent isolated sleep paralysis
  3. Nightmare disorder

Other parasomnias

  1. Exploding head syndrome
  2. Sleep-related hallucinations
  3. Sleep enuresis
  4. Parasomnia due to a medical disorder
  5. Parasomnia due to a medication or substance
  6. Parasomnia, unspecified

Isolated symptoms and normal variants

  1. Sleep talking
  1. Restless legs syndrome
  2. Periodic limb movement disorder
  3. Sleep-related leg cramps
  4. Sleep-related bruxism
  5. Sleep-related rhythmic movement disorder
  6. Benign sleep myoclonus of infancy
  7. Propriospinal myoclonus at sleep onset
  8. Sleep-related movement disorder due to a medical disorder
  9. Sleep-related movement disorder due to a medication or substance
  10. Sleep-related movement disorder, unspecified

Isolated symptoms and normal variants

  1. Excessive fragmentary myoclonus
  2. Hypnagogic foot tremor and alternating leg muscle activation
  3. Sleep starts (hypnic jerks)

7. Other sleep disorders

Other sleep-related symptoms or events that do not meet the standard definition of a sleep disorder.

In 2023, the AASM revised the third edition with the International Classification of Sleep Disorders, third edition, text revision (ICSD-3-TR). [6]

See also

Related Research Articles

<span class="mw-page-title-main">Sleep disorder</span> Medical disorder of a persons sleep patterns

A sleep disorder, or somnipathy, is a medical disorder of an individual's sleep patterns. Some sleep disorders are severe enough to interfere with normal physical, mental, social and emotional functioning. Sleep disorders are frequent and can have serious consequences on patients' health and quality of life. Polysomnography and actigraphy are tests commonly ordered for diagnosing sleep disorders.

<span class="mw-page-title-main">Delayed sleep phase disorder</span> Chronic sleep disorder

Delayed sleep phase disorder (DSPD), more often known as delayed sleep phase syndrome and also as delayed sleep–wake phase disorder, is the delaying of a person's circadian rhythm compared to those of societal norms. The disorder affects the timing of biological rhythms including sleep, peak period of alertness, core body temperature, and hormonal cycles. People with this disorder are often called night owls.

Dyssomnias are a broad classification of sleeping disorders involving difficulty getting to sleep, remaining asleep, or of excessive sleepiness.

<span class="mw-page-title-main">Night terror</span> Sleep disorder causing feelings of panic or dread

Night terror, also called sleep terror, is a sleep disorder causing feelings of panic or dread and typically occurring during the first hours of stage 3–4 non-rapid eye movement (NREM) sleep and lasting for 1 to 10 minutes. It can last longer, especially in children. Sleep terror is classified in the category of NREM-related parasomnias in the International Classification of Sleep Disorders. There are two other categories: REM-related parasomnias and other parasomnias. Parasomnias are qualified as undesirable physical events or experiences that occur during entry into sleep, during sleep, or during arousal from sleep.

Somnolence is a state of strong desire for sleep, or sleeping for unusually long periods. It has distinct meanings and causes. It can refer to the usual state preceding falling asleep, the condition of being in a drowsy state due to circadian rhythm disorders, or a symptom of other health problems. It can be accompanied by lethargy, weakness and lack of mental agility.

Hypersomnia is a neurological disorder of excessive time spent sleeping or excessive sleepiness. It can have many possible causes and can cause distress and problems with functioning. In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), hypersomnolence, of which there are several subtypes, appears under sleep-wake disorders.

Sexsomnia, also known as sleep sex, is a distinct form of parasomnia, or an abnormal activity that occurs while an individual is asleep. Sexsomnia is characterized by an individual engaging in sexual acts while in non-rapid eye movement (NREM) sleep. Sexual behaviors that result from sexsomnia are not to be mistaken with normal nocturnal sexual behaviors, which do not occur during NREM sleep. Sexual behaviors that are viewed as normal during sleep and are accompanied by extensive research and documentation include nocturnal emissions, nocturnal erections, and sleep orgasms.

Non-24-hour sleep–wake disorder is one of several chronic circadian rhythm sleep disorders (CRSDs). It is defined as a "chronic steady pattern comprising [...] daily delays in sleep onset and wake times in an individual living in a society". Symptoms result when the non-entrained (free-running) endogenous circadian rhythm drifts out of alignment with the light–dark cycle in nature. Although this sleep disorder is more common in blind people, affecting up to 70% of the totally blind, it can also affect sighted people. Non-24 may also be comorbid with bipolar disorder, depression, and traumatic brain injury. The American Academy of Sleep Medicine (AASM) has provided CRSD guidelines since 2007 with the latest update released in 2015.

Periodic limb movement disorder (PLMD) is a sleep disorder where the patient moves limbs involuntarily and periodically during sleep, and has symptoms or problems related to the movement. PLMD should not be confused with restless legs syndrome (RLS), which is characterized by a voluntary response to an urge to move legs due to discomfort. PLMD on the other hand is involuntary, and the patient is often unaware of these movements altogether. Periodic limb movements (PLMs) occurring during daytime period can be found but are considered as a symptom of RLS; only PLMs during sleep can suggest a diagnosis of PLMD.

<span class="mw-page-title-main">Somnology</span> Scientific study of sleep

Somnology is the scientific study of sleep. It includes clinical study and treatment of sleep disorders and irregularities. Sleep medicine is a subset of somnology. Hypnology has a similar meaning but includes hypnotic phenomena.

The American Academy of Sleep Medicine (AASM) is a United States professional society for the medical subspecialty of sleep medicine which includes disorders of circadian rhythms. It was established in 1975.

Parasomnias are a category of sleep disorders that involve abnormal movements, behaviors, emotions, perceptions, and dreams that occur while falling asleep, sleeping, between sleep stages, or during arousal from sleep. Parasomnias are dissociated sleep states which are partial arousals during the transitions between wakefulness, NREM sleep, and REM sleep, and their combinations.

<span class="mw-page-title-main">Sleep medicine</span> Medical specialty devoted to the diagnosis and therapy of sleep disturbances and disorders

Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and disorders. From the middle of the 20th century, research has provided increasing knowledge of, and answered many questions about, sleep–wake functioning. The rapidly evolving field has become a recognized medical subspecialty in some countries. Dental sleep medicine also qualifies for board certification in some countries. Properly organized, minimum 12-month, postgraduate training programs are still being defined in the United States. In some countries, the sleep researchers and the physicians who treat patients may be the same people.

<span class="mw-page-title-main">Narcolepsy</span> Human sleep disorder

Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM sleep. The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. People with narcolepsy tend to sleep about the same number of hours per day as people without it, but the quality of sleep is typically compromised.

Idiopathic hypersomnia(IH) is a neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness (EDS). Idiopathic hypersomnia was first described by Bedrich Roth in 1976, and it can be divided into two forms: polysymptomatic and monosymptomatic. The condition typically becomes evident in early adulthood and most patients diagnosed with IH will have had the disorder for many years prior to their diagnosis. As of August 2021, an FDA-approved medication exists for IH called Xywav, which is an oral solution of calcium, magnesium, potassium, and sodium oxybates; in addition to several off-label treatments (primarily FDA-approved narcolepsy medications).

A sleep-related breathing disorder is a sleep disorder in which abnormalities in breathing occur during sleep that may or may not be present while awake. According to the International Classification of Sleep Disorders, sleep-related breathing disorders are classified as follows:

Classification of sleep disorders comprises systems for classifying medical disorders associated with sleep. Systems have changed, increasingly using technological discoveries to advance the understanding of sleep and recognition of sleep disorders.

A confusional arousal is medical condition where a person awakened from sleep shows mental confusion for at least several minutes. Complete or partial amnesia of the episodes may be present.

<span class="mw-page-title-main">Behavioral sleep medicine</span>

Behavioral sleep medicine (BSM) is a field within sleep medicine that encompasses scientific inquiry and clinical treatment of sleep-related disorders, with a focus on the psychological, physiological, behavioral, cognitive, social, and cultural factors that affect sleep, as well as the impact of sleep on those factors. The clinical practice of BSM is an evidence-based behavioral health discipline that uses primarily non-pharmacological treatments. BSM interventions are typically problem-focused and oriented towards specific sleep complaints, but can be integrated with other medical or mental health treatments. The primary techniques used in BSM interventions involve education and systematic changes to the behaviors, thoughts, and environmental factors that initiate and maintain sleep-related difficulties.

References

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