List of oncogenic bacteria

Bacteria involved in causing and treating cancers

This is a list of bacteria that have been identified as promoting or causing:

• Uncontrolled growth of tissue in the body
• Cancer
• Carcinomas
• Tumors (including benign or slow growing)
• Neoplasms
• Sarcomas
• Precancerous lesions
• Coinfectious agent promoting the above growths

Species or genera

Species or genera	Possibly associated cancers	Ref
Bacteroides fragilis	Colon cancer.	[1]
Borrelia burgdorferi	MALT lymphoma.	[2]
Campylobacter jejuni	Immunoproliferative small intestinal disease (IPSID), which is rare a type of MALT lymphoma.	[2]
Chlamydia pneumonia	Lung MALT lymphoma.	[2]
Chlamydia trachomatis (chlamydia)	Cervical cancer.	[2]
Chlamydophila psittaci	Ocular/adnexal lymphoma (forms of eye cancer).	[2]
Clostridium ssp	Colon cancer.	[2]
Cutibacterium acnes	Bladder and prostate cancer.	[2]
Fusobacterium nucleatum	Colorectal cancer	[3]
Helicobacter bilis	Biliary cancers (such as gallbladder and biliary tract cancers).	[2]
Helicobacter bizzozeronii	Gastric MALT lymphoma.	[2]
Helicobacter felis	Gastric MALT lymphoma.	[2]
Helicobacter heilmannii	Marginal zone B-cell lymphoma of the stomach.	[2] [4]
Helicobacter hepaticus	Biliary cancer.	[2]
Helicobacter pylori	Stomach cancer, Marginal zone B-cell lymphoma of the stomach, and bile duct cancer	[2] [5] [6]
Helicobacter salomonis	Gastric MALT lymphoma.	[2]
Helicobacter suis	Gastric MALT lymphoma.	[2]
Mycoplasma spp	Stomach, colon, ovarian, and lung cancers (particularly M. fermentans, M. penetrans, M. hyorhinis).	[2]
Neisseria gonorrhoeae (gonorrhea)	Bladder cancer and possibly prostate cancer.	[2]
Salmonella enterica serovar Paratyphi	Biliary cancer.	[7] [8] [2]
Salmonella enterica serovar Typhimurium	Biliary cancer.	[9] [2]
Streptococcus bovis	Colorectal cancer	[10]
Treponema pallidum (syphilis)	Bladder cancer and possibly prostate cancer.	[2]

See also

• Carcinogenic bacteria
• Sexually transmitted disease
• Infectious causes of cancer
• Infections associated with diseases
• List of infectious diseases
• Timeline of peptic ulcer disease and Helicobacter pylori - featured list

References

1. Sinkovics, Joseph (2011). "Molecular biology of oncogenic inflammatory processes. I. Non-oncogenic and oncogenic pathogens, intrinsic inflammatory reactions without pathogens, and microRNA/DNA interactions (Review)". International Journal of Oncology. 40 (2): 305–49. doi: 10.3892/ijo.2011.1248 . ISSN   1019-6439. PMID   22076306.
2. Chang, A. H.; Parsonnet, J. (2010). "Role of Bacteria in Oncogenesis". Clinical Microbiology Reviews. 23 (4): 837–857. doi:10.1128/CMR.00012-10. ISSN   0893-8512. PMC   2952975 . PMID   20930075.
3. Kostic, Aleksandar D.; Chun, Eunyoung; Robertson, Lauren; Glickman, Jonathan N.; Gallini, Carey Ann; Michaud, Monia; Clancy, Thomas E.; Chung, Daniel C.; Lochhead, Paul; Hold, Georgina L.; El-Omar, Emad M.; Brenner, Dean; Fuchs, Charles S.; Meyerson, Matthew; Garrett, Wendy S. (2013-08-14). "Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment". Cell Host & Microbe. 14 (2): 207–215. doi:10.1016/j.chom.2013.07.007. ISSN   1931-3128. PMC   3772512 . PMID   23954159.
4. Schreuder MI, van den Brand M, Hebeda KM, Groenen PJ, van Krieken JH, Scheijen B (December 2017). "Novel developments in the pathogenesis and diagnosis of extranodal marginal zone lymphoma". Journal of Hematopathology. 10 (3–4): 91–107. doi:10.1007/s12308-017-0302-2. PMC   5712330 . PMID   29225710.
5. Traulsen, Jan; Zagami, Claudia; Daddi, Alice Anna; Boccellato, Francesco (2021-03-01). "Molecular modelling of the gastric barrier response, from infection to carcinogenesis". Best Practice & Research Clinical Gastroenterology. 50–51 101737. doi:10.1016/j.bpg.2021.101737. ISSN   1521-6918. PMID   33975688. S2CID   233900318.
6. Bravo D, Hoare A, Soto C, Valenzuela MA, Quest AF (July 2018). "Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects". World Journal of Gastroenterology. 24 (28): 3071–3089. doi: 10.3748/wjg.v24.i28.3071 . PMC   6064966 . PMID   30065554.
7. Sepe, Ludovico P.; Hartl, Kimberly; Iftekhar, Amina; Berger, Hilmar; Kumar, Naveen; Goosmann, Christian; Chopra, Sascha; Schmidt, Sven Christian; Gurumurthy, Rajendra Kumar; Meyer, Thomas F.; Boccellato, Francesco (2020-09-22). McClane, Bruce A. (ed.). "Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells". mBio. 11 (5): e01911–20, /mbio/11/5/mBio.01911–20.atom. doi:10.1128/mBio.01911-20. ISSN   2150-7511. PMC   7512552 . PMID   32963006.
8. Boccellato, Francesco; Meyer, Thomas F. (June 2015). "Bacteria Moving into Focus of Human Cancer". Cell Host & Microbe. 17 (6): 728–730. doi: 10.1016/j.chom.2015.05.016 . ISSN   1931-3128. PMID   26067598.
9. Scanu, Tiziana; Spaapen, Robbert M.; Bakker, Jeroen M.; Pratap, Chandra Bhan; Wu, Lin-en; Hofland, Ingrid; Broeks, Annegien; Shukla, Vijay Kumar; Kumar, Mohan; Janssen, Hans; Song, Ji-Ying (June 2015). "Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma". Cell Host & Microbe. 17 (6): 763–774. doi: 10.1016/j.chom.2015.05.002 . PMID   26028364.
10. Klein, Robert S.; Recco, Rose A.; Catalano, Michela T.; Edberg, Stephen C.; Casey, Joan I.; Steigbigel, Neal H. (1977-10-13). "Association of Streptococcus bovis with Carcinoma of the Colon" . New England Journal of Medicine. 297 (15): 800–802. doi:10.1056/NEJM197710132971503. ISSN   0028-4793. PMID   408687.

Further reading

• Cornwall, Claudia. Catching cancer : the quest for its viral and bacterial causes. Rowman & Littlefield Publishers (2013) Lanham, Maryland. ISBN   9781442215207.