List of infectious diseases

Last updated

This is a list of infectious diseases arranged by name, along with the infectious agents that cause them, the vaccines that can prevent or cure them when they exist and their current status. Some on the list are vaccine-preventable diseases.

Contents

List

Infectious agentCommon nameDiagnosisTreatmentVaccine(s)
Acinetobacter baumannii Acinetobacter infectionsCultureSupportive careNo
Actinomyces israelii , Actinomyces gerencseriae and Propionibacterium propionicus Actinomycosis Histologic findings Penicillin, doxycycline, and sulfonamides No
Adenoviridae Adenovirus infection Antigen detection, polymerase chain reaction assay, virus isolation, and serology Most infections are mild and require no therapy or only symptomatic treatment. Under research [1]
Trypanosoma brucei African sleeping sickness (African trypanosomiasis)Identification of trypanosomes in a sample by microscopic examination Fexinidazole by mouth or pentamidine by injection for T. b. gambiense.

Suramin by injection is used for T. b. rhodesiense

Under research [2]
HIV (Human immunodeficiency virus) AIDS (acquired immunodeficiency syndrome) Antibody test, p24 antigen test, PCRTreatment is typically a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus two nucleoside analog reverse transcriptase inhibitors (NRTIs) Under research [3]
Entamoeba histolytica Amoebiasis MicroscopyThose with symptoms require treatment with an amoebicidal tissue-active agent and a luminal cysticidal agent. Individuals that are asymptomatic only need a luminal cysticidal agent.No
Anaplasma species Anaplasmosis indirect immunofluorescence antibody assay for IgGTetracycline drugs (including tetracycline, chlortetracycline, oxytetracycline, rolitetracycline, doxycycline, and minocycline) and imidocarb No
Angiostrongylus Angiostrongyliasis Lumbar puncture, brain imaging, serologyAlbendazoleNo
Anisakis Anisakiasis Gastroscopic examination, or histopathologic examination Albendazole No
Bacillus anthracis Anthrax Culture, PCRLarge doses of intravenous and oral antibiotics, such as fluoroquinolones (ciprofloxacin), doxycycline, erythromycin, vancomycin, or penicillin Yes
Arcanobacterium haemolyticum Arcanobacterium haemolyticum infection Culture in human blood agar plates erythromycin (proposed as the first-line drug), clindamycin, gentamicin, and cephalosporins No
Junin virus Argentine hemorrhagic fever Yes [4]
Ascaris lumbricoides Ascariasis Fecal smear Albendazole, mebendazole, levamisole and pyrantel pamoate No
Aspergillus species Aspergillosis Chest X-ray and CT, microscopy by silver stains Voriconazole and liposomal amphotericin B in combination with surgical debridement No
Astroviridae species Astrovirus infection Electron microscopy, enzyme-immunoassay (ELISA), immunofluorescence, and polymerase chain reaction Supportive careNo
Babesia species Babesiosis Giemsa-stained thin-film blood smear Atovaquone and azithromycin. In life-threatening cases, exchange transfusion is performed.No
Bacillus cereus Bacillus cereus infectionCulture Vancomycin No
multiple bacteria Bacterial meningitis Lumbar puncture (contraindicated if there is a mass in the brain or the intracranial pressure is elevated), CT or MRIAntibioticsNo
multiple bacteria Bacterial pneumonia Sputum Gram stain and culture, Chest radiographyAntibioticsNo
List of bacterial vaginosis microbiota Bacterial vaginosis Gram stain and whiff test Metronidazole or clindamycin No
Bacteroides species Bacteroides infectionNo
Balantidium coli Balantidiasis microscopic examination of stools, or colonoscopy or sigmoidoscopy Tetracycline, metronidazole or iodoquinol No
Bartonella Bartonellosis microscopy, serology, and PCR AntibioticsNo
Baylisascaris species Baylisascaris infectionNo
BK virus BK virus infectionNo
Piedraia hortae Black piedra Stain or cultureAntifungal shampoos such as pyrithione zinc, formaldehyde and salicylic acid No
Blastocystis species Blastocystosis microscopic examination of a chemically preserved stool specimenLack of scientific study to support the efficacy of any particular treatmentNo
Blastomyces dermatitidis Blastomycosis KOH prep, cytology, or histology Itraconazole or ketoconazole No
Machupo virus Bolivian hemorrhagic fever No
Clostridium botulinum ; Note: Botulism is not an infection by Clostridium botulinum but caused by the intake of botulinum toxin. Botulism (and Infant botulism) Enzyme-linked immunosorbent assays (ELISAs), electrochemiluminescent (ECL) testsBotulism antitoxin and supportive careNo
Sabiá virus Brazilian hemorrhagic fever No
Brucella species Brucellosis Culture Tetracyclines, rifampicin, and the aminoglycosides streptomycin and gentamicin Yes [5]
Yersinia pestis Bubonic plague Culture Aminoglycosides such as streptomycin and gentamicin, tetracyclines (especially doxycycline), and the fluoroquinolone ciprofloxacin Under research [6]
usually Burkholderia cepacia and other Burkholderia species Burkholderia infectionNo
Mycobacterium ulcerans Buruli ulcer real-time PCR The most widely used antibiotic regimen is once daily oral rifampicin plus twice daily oral clarithromycin.No
Caliciviridae species Calicivirus infection (Norovirus and Sapovirus)No
Campylobacter species Campylobacteriosis Stool culture Erythromycin can be used in children, and tetracycline in adults.No
usually Candida albicans and other Candida species Candidiasis (Moniliasis; Thrush)oral candidiasis, the person's mouth for white patches and irritation.

vaginal candidiasis, vaginal itching or soreness, pain during sexual intercourse

Antifungal medications No
Intestinal disease by Capillaria philippinensis , hepatic disease by Capillaria hepatica and pulmonary disease by Capillaria aerophila Capillariasis No
Streptococcus mutans Dental caries Under research [7]
Bartonella bacilliformis Carrion's disease Peripheral blood smear with Giemsa stain, Columbia blood agar cultures, immunoblot, indirect immunofluorescence, and PCR Fluoroquinolones (such as ciprofloxacin) or chloramphenicol in adults and chloramphenicol plus beta-lactams in childrenNo
Bartonella henselae Cat-scratch disease Polymerase chain reaction Azithromycin No
usually Group A Streptococcus and Staphylococcus Cellulitis history and physical examinationPenicillinase-resistant semisynthetic penicillin or a first-generation cephalosporin No
Trypanosoma cruzi Chagas disease (American trypanosomiasis) Microscopic examination of fresh anticoagulated blood, or its buffy coat, for motile parasites; or by preparation of thin and thick blood smears stained with Giemsa. Benznidazole and nifurtimox (though benznidazole is the only drug available in most of Latin America)Under research [8]
Haemophilus ducreyi Chancroid Clinical diagnosisThe CDC recommendation is either a single oral dose (1 gram) of azithromycin, a single IM dose (250 mg) of ceftriaxone, oral (500 mg) of erythromycin three times a day for seven days, or oral (500 mg) of ciprofloxacin twice a day for three days.No
Varicella zoster virus (VZV) Chickenpox The diagnosis of chickenpox is primarily based on the signs and symptoms, with typical early symptoms followed by a characteristic rash. Aciclovir Yes
Alphavirus Chikungunya Laboratory criteria include a decreased lymphocyte count consistent with viremia.

Definitive laboratory diagnosis can be accomplished through viral isolation, RT-PCR, or serological diagnosis.

Supportive care Under research [9]
Chlamydia trachomatis Chlamydia Nucleic acid amplification tests (NAAT), such as polymerase chain reaction (PCR), transcription mediated amplification (TMA), and the DNA strand displacement amplification (SDA) azithromycin, doxycycline, erythromycin, levofloxacin or ofloxacin No
Chlamydophila pneumoniae Chlamydophila pneumoniae infection (Taiwan acute respiratory agent or TWAR)No
Vibrio cholerae Cholera A rapid dipstick test is available. oral rehydration therapy (ORT) Yes
usually Fonsecaea pedrosoi Chromoblastomycosis microscopy (KOH scrapings) Itraconazole, an antifungal azole, is given orally, with or without flucytosine.No
Batrachochytrium dendrabatidis Chytridiomycosis No
Clonorchis sinensis Clonorchiasis No
Clostridium difficile Clostridium difficile colitis Colonoscopy or sigmoidoscopy, cytotoxicity assay, toxin ELISA Vancomycin or fidaxomicin by mouthNo
Coccidioides immitis and Coccidioides posadasii Coccidioidomycosis No
Colorado tick fever virus (CTFV) Colorado tick fever (CTF)No
usually rhinoviruses and coronaviruses Common cold (Acute viral rhinopharyngitis; Acute coryza)Based on symptomsSupportive careNo
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Coronavirus disease 2019 (COVID-19) Yes
Coxsackie B virus Coxsackie B virus infectionEnterovirus infection is diagnosed mainly via serological tests such as ELISA and from cell culture.There is no well-accepted treatment for the Coxsackie B group of viruses.Under research [10]
PRNP Creutzfeldt–Jakob disease (CJD)No
Crimean-Congo hemorrhagic fever virus Crimean-Congo hemorrhagic fever (CCHF)No
Cryptococcus neoformans Cryptococcosis India ink of the cerebrospinal fluid (CSF) Intravenous Amphotericin B combined with flucytosine by mouthNo
Cryptosporidium species Cryptosporidiosis No
usually Ancylostoma braziliense ; multiple other parasites Cutaneous larva migrans (CLM)No
Cyclospora cayetanensis Cyclosporiasis No
Taenia solium Cysticercosis No
Cytomegalovirus Cytomegalovirus infectionBlood and urine tests, biopsyCidofovir, foscarnet, ganciclovir, valganciclovir Under research [11]
Dengue viruses (DEN-1, DEN-2, DEN-3 and DEN-4) – Flaviviruses Dengue fever Clinical diagnosisTreatment depends on the symptoms. Yes
Green algae Desmodesmus armatus Desmodesmus infectionNo
Dientamoeba fragilis Dientamoebiasis No
Corynebacterium diphtheriae Diphtheria Laboratory criteria
  • Isolation of C. diphtheriae culture
  • Histopathologic diagnosis

Toxin demonstration

  • In vivo tests (guinea pig inoculation)
  • In vitro test: Elek's gel precipitation test, PCR, ELISA, ICA

Clinical criteria

  • URT illness with sore throat
  • Low-grade fever
  • An adherent, dense, grey pseudomembrane covering the posterior aspect of the pharynx
Metronidazole, Erythromycin, Procaine penicillin G Yes
Diphyllobothrium Diphyllobothriasis No
Dracunculus medinensis Dracunculiasis No
Eastern equine encephalitis virus Eastern equine encephalitis (EEE)Blood tests Corticosteroids, anticonvulsants, and supportive measures (treating symptoms)Under research [12]
Ebolavirus (EBOV) Ebola hemorrhagic fever Yes
Echinococcus species Echinococcosis Imaging, Serology testSurgical removal of the cysts combined with chemotherapyNo
Ehrlichia species Ehrlichiosis Under research [13]
Enterobius vermicularis Enterobiasis (Pinworm infection)No
Enterococcus species Enterococcus infectionNo
Enterovirus species Enterovirus infectionNo
Rickettsia prowazekii Epidemic typhus No
Parvovirus B19 Erythema infectiosum (Fifth disease)No
Human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) Exanthem subitum (Sixth disease)No
Fasciola hepatica and Fasciola gigantica Fasciolasis No
Fasciolopsis buski Fasciolopsiasis No
PRNP Fatal familial insomnia (FFI)No
Filarioidea superfamily Filariasis No
Clostridium perfringens Food poisoning by Clostridium perfringens Stool testSupportive careNo
multiple Free-living amebic infection No
Fusobacterium species Fusobacterium infectionNo
usually Clostridium perfringens ; other Clostridium species Gas gangrene (Clostridial myonecrosis)No
Geotrichum candidum Geotrichosis No
PRNP Gerstmann-Sträussler-Scheinker syndrome (GSS)No
Giardia lamblia Giardiasis Detection of antigens on the surface of organisms in stoolTreatment is not always necessary. If medications are needed, a nitroimidazole medication is used such as metronidazole, tinidazole, secnidazole or ornidazole.No
Burkholderia mallei Glanders No
Gnathostoma spinigerum and Gnathostoma hispidum Gnathostomiasis No
Neisseria gonorrhoeae Gonorrhea Gram stain and culture Ceftriaxone by injection and azithromycin by mouthUnder research [14]
Klebsiella granulomatis Granuloma inguinale (Donovanosis)No
Streptococcus pyogenes Group A streptococcal infection CulturePenicillinNo
Streptococcus agalactiae Group B streptococcal infection Gram stainPenicillin and ampicillinNo
Haemophilus influenzae Haemophilus influenzae infectionGram stainIn severe cases, cefotaxime and ceftriaxone delivered into the bloodstream, and for the less severe cases, an association of ampicillin and sulbactam, cephalosporins of the second and third generation, or fluoroquinolones are preferred. Yes
Enteroviruses, mainly Coxsackie A virus and enterovirus 71 (EV71) Hand, foot and mouth disease (HFMD)A diagnosis usually can be made by the presenting signs and symptoms alone. If the diagnosis is unclear, a throat swab or stool specimen may be taken.Medications are usually not needed as hand, foot, and mouth disease is a viral disease that typically resolves on its own.Under research [15] [16]
Sin Nombre virus Hantavirus Pulmonary Syndrome (HPS)No
Heartland virus Heartland virus diseaseNo
Helicobacter pylori Helicobacter pylori infectionNo
Escherichia coli O157:H7, O111 and O104:H4 Hemolytic-uremic syndrome (HUS)First diagnosis of aHUS is often made in the context of an initial, complement-triggering infection, and Shiga-toxin has also been implicated as a trigger that identifies patients with aHUS.Treatment involves supportive care and may include dialysis, steroids, blood transfusions, and plasmapheresis.No
Bunyaviridae species Hemorrhagic fever with renal syndrome (HFRS)HFRS is difficult to diagnose on clinical grounds alone and serological evidence is often needed.There is no cure for HFRS. Treatment involves supportive therapy including renal dialysis.No
Hendra virus Hendra virus infectionNo
Hepatitis A virus Hepatitis A Blood tests Supportive care, liver transplantation Yes
Hepatitis B virus Hepatitis B Blood tests Antiviral medication (tenofovir, interferon), liver transplantation Yes
Hepatitis C virus Hepatitis C Blood testing for antibodies or viral RNA Antivirals (sofosbuvir, simeprevir, others) Under research [17]
Hepatitis D Virus Hepatitis D Immunoglobulin GAntivirals, pegylated interferon alphaNo
Hepatitis E virus Hepatitis E Hepatitis E virus (HEV)Rest, ribavirin (if chronic) Yes
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) Herpes simplex Based on symptoms, PCR, viral culture Aciclovir, valaciclovir, paracetamol (acetaminophen), topical lidocaineNo
Histoplasma capsulatum Histoplasmosis Histoplasmosis can be diagnosed by samples containing the fungus taken from sputum (via bronchoalveolar lavage), blood, or infected organs.In the majority of immunocompetent individuals, histoplasmosis resolves without any treatment. Typical treatment of severe disease first involves treatment with amphotericin B, followed by oral itraconazole.No
Ancylostoma duodenale and Necator americanus Hookworm infection Under research [18]
Human bocavirus (HBoV) Human bocavirus infectionNo
Ehrlichia ewingii Human ewingii ehrlichiosis The diagnosis can be confirmed by using PCR. A peripheral blood smear can also be examined for intracytoplasmic inclusions called morulae. Doxycycline No
Anaplasma phagocytophilum Human granulocytic anaplasmosis (HGA) PCR Doxycycline No
Human metapneumovirus (hMPV) Human metapneumovirus infectionNo
Ehrlichia chaffeensis Human monocytic ehrlichiosis PCR Doxycycline No
One of the human papillomaviruses Human papillomavirus (HPV) infection Yes
Human parainfluenza viruses (HPIV) Human parainfluenza virus infectionUnder research [19] [20]
Human T-lymphotropic virus 1 (HTLV-1) Human T-lymphotropic virus 1 infectionUnder research [21] [22]
Hymenolepis nana and Hymenolepis diminuta Hymenolepiasis Examination of the stool for eggs and parasites Praziquantel, niclosamide No
Epstein–Barr virus (EBV) Epstein–Barr virus infectious mononucleosis (Mono)Diagnostic modalities for infectious mononucleosis include: Infectious mononucleosis is generally self-limiting, so only symptomatic or supportive treatments are used. Under research [23]
Orthomyxoviridae species Influenza (flu)Diagnostic methods that can identify influenza include viral cultures, antibody- and antigen-detecting tests, and nucleic acid-based tests.Treatment of influenza in cases of mild or moderate illness is supportive and includes anti-fever medications such as acetaminophen and ibuprofen, adequate fluid intake to avoid dehydration, and resting at home.Under research [24]
Yes
Isospora belli Isosporiasis Microscopic demonstration of the large typically shaped oocysts is the basis for diagnosis. Trimethoprim-sulfamethoxazole No
Japanese encephalitis virus Japanese encephalitis Available tests detecting JE virus-specific IgM antibodies in serum and/or cerebrospinal fluid, for example by IgM capture ELISA.Supportive Yes
unknown; evidence supports that it is infectious Kawasaki disease Based on symptoms, ultrasound of the heart Aspirin, immunoglobulin No
multiple Keratitis Infectious keratitis generally requires urgent antibacterial, antifungal, or antiviral therapy to eliminate the pathogen.No
Kingella kingae Kingella kingae infectionNo
PRNP Kuru AutopsyNoneNo
Lassa virus Lassa fever Laboratory testingSupportiveNo
Legionella pneumophila Legionellosis (Legionnaires' disease)Urinary antigen test, sputum culture Effective antibiotics include most macrolides, tetracyclines, ketolides, and quinolones.No
Legionella pneumophila Pontiac fever No
Leishmania species Leishmaniasis Hematology laboratory by direct visualization of the amastigotes (Leishman–Donovan bodies).For visceral leishmaniasis in India, South America, and the Mediterranean, liposomal amphotericin B is the recommended treatment and is often used as a single dose. Under research [25]
Mycobacterium leprae and Mycobacterium lepromatosis Leprosy In countries where people are frequently infected, a person is considered to have leprosy if they have one of the following two signs:
  • Skin lesion consistent with leprosy and with definite sensory loss.
  • Positive skin smears.
Rifampicin, dapsone, clofazimine Under research [26]
Leptospira species Leptospirosis Testing blood for antibodies against the bacterium or its DNA Doxycycline, penicillin, ceftriaxone Yes
Listeria monocytogenes Listeriosis Culture of blood or spinal fluid Ampicillin, gentamicin No
Borrelia burgdorferi , Borrelia garinii , and Borrelia afzelii Lyme disease (Lyme borreliosis)Based on symptoms, tick exposure, blood tests Doxycycline, amoxicillin, ceftriaxone, cefuroxime Under research [27]
Wuchereria bancrofti and Brugia malayi Lymphatic filariasis (Elephantiasis) Microscopic examination of blood Albendazole with ivermectin or diethylcarbamazine No
Lymphocytic choriomeningitis virus (LCMV) Lymphocytic choriomeningitis Blood testSymptomatic and supportiveNo
Plasmodium species Malaria Examination of the blood, antigen detection tests Antimalarial medication Yes
Marburg virus Marburg hemorrhagic fever (MHF)Blood testSupportiveUnder research [28]
Measles virus Measles Onset of fever and malaise about 10 days after exposure to the measles virus, followed by the emergence of cough, coryza, and conjunctivitis that worsen in severity over 4 days of appearing. Observation of Koplik's spots is also diagnostic. Supportive care Yes
Middle East respiratory syndrome–related coronavirus Middle East respiratory syndrome (MERS) rRT-PCR testing Symptomatic and supportive Under research [29]
Burkholderia pseudomallei Melioidosis (Whitmore's disease)Growing the bacteria in culture mediums Ceftazidime, meropenem, co-trimoxazole No
multiple Meningitis Lumbar puncture Antibiotics, antivirals, steroids No
Neisseria meningitidis Meningococcal disease Treatment in primary care usually involves intramuscular administration of benzylpenicillin. Once in the hospital, the antibiotics of choice are usually IV broad spectrum 3rd generation cephalosporins. Yes
usually Metagonimus yokagawai Metagonimiasis Metagonimiasis is diagnosed by eggs seen in feces. Praziquantel No
Microsporidia phylum Microsporidiosis PCR Fumagillin has been used in the treatment. Another agent used is albendazole.No
Molluscum contagiosum virus (MCV) Molluscum contagiosum (MC)Based on appearance Cimetidine, podophyllotoxin No
Monkeypox virus Mpox Testing for viral DNASupportive, antivirals, vaccinia immune globulin Yes
Mumps virus Mumps Antibody testing, viral cultures, and reverse transcription polymerase chain reaction Supportive Yes
Rickettsia typhi Murine typhus (Endemic typhus)Early diagnosis continued to be based on clinical suspicion.The most effective antibiotics include tetracycline and chloramphenicol.No
Mycoplasma pneumoniae Mycoplasma pneumonia Chest X-Ray, Chest CT, blood test Erythromycin, doxycycline No
Mycoplasma genitalium Mycoplasma genitalium infectionNucleic acid amplification test Azithromycin, moxifloxacin No
numerous species of bacteria (Actinomycetoma) and fungi (Eumycetoma) Mycetoma Ultrasound, fine needle aspiration Antibiotics or antifungal medicationNo
parasitic dipterous fly larvae Myiasis Examination and serologic testingPetroleum jelly over the central punctumNo
most commonly Chlamydia trachomatis and Neisseria gonorrhoeae Neonatal conjunctivitis (Ophthalmia neonatorum)Antibiotic ointment (erythromycin, tetracycline, or rarely silver nitrate or Argyrol)No
Nipah virus Nipah virus infection Under research [30]
Norovirus Norovirus Based on symptoms Supportive care Under research [31]
PRNP (New) Variant Creutzfeldt–Jakob disease (vCJD, nvCJD)No
usually Nocardia asteroides and other Nocardia species Nocardiosis chest x-ray to analyze the lungs, a bronchoscopy, a brain/lung/skin biopsy, or a sputum culture. trimethoprim/sulfamethoxazole or high doses of sulfonamides No
Onchocerca volvulus Onchocerciasis (River blindness)Under research [32]
Opisthorchis viverrini and Opisthorchis felineus Opisthorchiasis No
Paracoccidioides brasiliensis Paracoccidioidomycosis (South American blastomycosis)No
usually Paragonimus westermani and other Paragonimus species Paragonimiasis No
Pasteurella species Pasteurellosis No
Pediculus humanus capitis Pediculosis capitis (Head lice)No
Pediculus humanus corporis Pediculosis corporis (Body lice)No
Pthirus pubis Pediculosis pubis (pubic lice, crab lice)No
multiple Pelvic inflammatory disease (PID)Based on symptoms, ultrasound, laparoscopic surgery Typical regimens include cefoxitin or cefotetan plus doxycycline, and clindamycin plus gentamicin.No
Bordetella pertussis Pertussis (whooping cough) Nasopharyngeal swab erythromycin, clarithromycin, or azithromycin Yes
Yersinia pestis Plague Finding the bacterium in a lymph node, blood, sputum Gentamicin and a fluoroquinolone Under research [6]
Streptococcus pneumoniae Pneumococcal infection Culture cephalosporins, and fluoroquinolones such as levofloxacin and moxifloxacin Yes
Pneumocystis jirovecii Pneumocystis pneumonia (PCP) chest X-ray and an arterial oxygen level trimethoprim/sulfamethoxazole No
multiple Pneumonia Based on symptoms, chest X-ray Antibiotics, antivirals, oxygen therapy No
Poliovirus Poliomyelitis Finding the virus in the feces or antibodies in the blood supportive care Yes
Prevotella species Prevotella infectionNo
usually Naegleria fowleri Primary amoebic meningoencephalitis (PAM)flagellation test Miltefosine, fluconazole, amphotericin B, posaconazole, voriconazole, targeted temperature management No
JC virus Progressive multifocal leukoencephalopathy finding JC virus DNA in spinal fluid, brain CTNo
Chlamydophila psittaci Psittacosis Culture tetracyclines and chloramphenicol No
Coxiella burnetii Q fever Based on serology doxycycline, tetracycline, chloramphenicol, ciprofloxacin, and ofloxacin Yes
Rabies virus Rabies fluorescent antibody test (FAT)Supportive care Yes
Borrelia hermsii , Borrelia recurrentis , and other Borrelia species Relapsing fever blood smear Tetracycline-class antibioticsNo
Respiratory syncytial virus (RSV) Respiratory syncytial virus infectionA variety of laboratory testsTreatment for RSV infection is focused primarily on supportive care. Under research [33]
Rhinosporidium seeberi Rhinosporidiosis No
Rhinovirus Rhinovirus infectionNo
Rickettsia species Rickettsial infectionNo
Rickettsia akari Rickettsialpox No
Rift Valley fever virus Rift Valley fever (RVF)No
Rickettsia rickettsii Rocky Mountain spotted fever (RMSF)No
Rotavirus Rotavirus infection Yes
Rubella virus Rubella Yes
Salmonella species Salmonellosis No
SARS coronavirus Severe acute respiratory syndrome (SARS)Under research [34]
Sarcoptes scabiei Scabies No
Group A Streptococcus species Scarlet fever No
Schistosoma species Schistosomiasis Under research [35]
multiple Sepsis No
Shigella species Shigellosis (bacillary dysentery)No
Varicella zoster virus (VZV) Shingles (Herpes zoster) Yes [36]
Variola major or Variola minor Smallpox (variola) Yes
Sporothrix schenckii Sporotrichosis No
Staphylococcus species Staphylococcal food poisoning No
Staphylococcus species Staphylococcal infection No
Strongyloides stercoralis Strongyloidiasis No
Measles virus Subacute sclerosing panencephalitis Yes
Treponema pallidum Bejel, Syphilis, and Yaws Under research [37]
Taenia species Taeniasis No
Clostridium tetani Tetanus (lockjaw) Yes
Tick-borne encephalitis virus (TBEV) Tick-borne encephalitis Yes
usually Trichophyton species Tinea barbae (barber's itch)No
usually Trichophyton tonsurans Tinea capitis (ringworm of the scalp)No
usually Trichophyton species Tinea corporis (ringworm of the body)No
usually Epidermophyton floccosum , Trichophyton rubrum , and Trichophyton mentagrophytes Tinea cruris (Jock itch)No
Trichophyton rubrum Tinea manum (ringworm of the hand)No
usually Hortaea werneckii Tinea nigra No
usually Trichophyton species Tinea pedis (athlete's foot)No
usually Trichophyton species Tinea unguium (onychomycosis)No
Malassezia species Tinea versicolor (Pityriasis versicolor)No
Staphylococcus aureus or Streptococcus pyogenes Toxic shock syndrome (TSS)Under research [38] [39]
Toxocara canis or Toxocara cati Toxocariasis (ocular larva migrans (OLM))No
Toxocara canis or Toxocara cati Toxocariasis (visceral larva migrans (VLM))No
Toxoplasma gondii Toxoplasmosis No
Chlamydia trachomatis Trachoma No
Trichinella spiralis Trichinosis No
Trichomonas vaginalis Trichomoniasis No
Trichuris trichiura Trichuriasis (whipworm infection)No
usually Mycobacterium tuberculosis Tuberculosis Yes
Francisella tularensis Tularemia Under research [40]
Salmonella enterica subsp. enterica, serovar typhi Typhoid fever Yes
Rickettsia Typhus fever No
Ureaplasma urealyticum Ureaplasma urealyticum infectionNo
Coccidioides immitis or Coccidioides posadasii . [41] Valley fever No
Venezuelan equine encephalitis virus Venezuelan equine encephalitis No
Guanarito virus Venezuelan hemorrhagic fever No
Vibrio vulnificus Vibrio vulnificus infection No
Vibrio parahaemolyticus Vibrio parahaemolyticus enteritis No
multiple viruses Viral pneumonia No
West Nile virus West Nile fever Under research [42]
Trichosporon beigelii White piedra (tinea blanca)No
Yersinia pseudotuberculosis Yersinia pseudotuberculosis infectionNo
Yersinia enterocolitica Yersiniosis No
Yellow fever virus Yellow fever Yes
Zeaspora fungus Zeaspora No
Zika virus Zika fever Under research [43]
Mucorales order (Mucormycosis) and Entomophthorales order (Entomophthoramycosis) Zygomycosis No

See also

Related Research Articles

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Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. Rotavirus is a genus of double-stranded RNA viruses in the family Reoviridae. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. Rotavirus A is the most common species, and these rotaviruses cause more than 90% of rotavirus infections in humans.

<span class="mw-page-title-main">Epstein–Barr virus</span> Virus of the herpes family

The Epstein–Barr virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. EBV is a double-stranded DNA virus. Epstein–Barr virus (EBV) is the first identified oncogenic virus, which establishes permanent infection in humans. EBV causes infectious mononucleosis and is also tightly linked to many malignant diseases. Various vaccine formulations underwent testing in different animals or in humans. However, none of them were able to prevent EBV infection and no vaccine has been approved to date.

<i>Human metapneumovirus</i> Species of virus

Human metapneumovirus is a negative-sense single-stranded RNA virus of the family Pneumoviridae and is closely related to the Avian metapneumovirus (AMPV) subgroup C. It was isolated for the first time in 2001 in the Netherlands by using the RAP-PCR technique for identification of unknown viruses growing in cultured cells. As of 2016, it was the second most common cause of acute respiratory tract illness in otherwise-healthy children under the age of 5 in a large US outpatient clinic.

<i>Orthomyxoviridae</i> Family of RNA viruses including the influenza viruses

Orthomyxoviridae is a family of negative-sense RNA viruses. It includes seven genera: Alphainfluenzavirus, Betainfluenzavirus, Gammainfluenzavirus, Deltainfluenzavirus, Isavirus, Thogotovirus, and Quaranjavirus. The first four genera contain viruses that cause influenza in birds and mammals, including humans. Isaviruses infect salmon; the thogotoviruses are arboviruses, infecting vertebrates and invertebrates. The Quaranjaviruses are also arboviruses, infecting vertebrates (birds) and invertebrates (arthropods).

Virus-like particles (VLPs) are molecules that closely resemble viruses, but are non-infectious because they contain no viral genetic material. They can be naturally occurring or synthesized through the individual expression of viral structural proteins, which can then self assemble into the virus-like structure. Combinations of structural capsid proteins from different viruses can be used to create recombinant VLPs. Both in-vivo assembly and in-vitro assembly have been successfully shown to form virus-like particles. VLPs derived from the Hepatitis B virus (HBV) and composed of the small HBV derived surface antigen (HBsAg) were described in 1968 from patient sera. VLPs have been produced from components of a wide variety of virus families including Parvoviridae, Retroviridae, Flaviviridae, Paramyxoviridae and bacteriophages. VLPs can be produced in multiple cell culture systems including bacteria, mammalian cell lines, insect cell lines, yeast and plant cells.

<i>Murine respirovirus</i> Sendai virus, virus of rodents

Murine respirovirus, formerly Sendai virus (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped, 150-200 nm–diameter, negative sense, single-stranded RNA virus of the family Paramyxoviridae. It typically infects rodents and it is not pathogenic for humans or domestic animals.

<span class="mw-page-title-main">Antibody-dependent enhancement</span> Antibodies rarely making an infection worse instead of better

Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. The suboptimal antibodies can result from natural infection or from vaccination. ADE may cause enhanced respiratory disease, but is not limited to respiratory disease. It has been observed in HIV, RSV virus and Dengue virus and is monitored for in vaccine development.

An attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable. Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent. These vaccines contrast to those produced by "killing" the pathogen.

Merkel cell polyomavirus was first described in January 2008 in Pittsburgh, Pennsylvania. It was the first example of a human viral pathogen discovered using unbiased metagenomic next-generation sequencing with a technique called digital transcriptome subtraction. MCV is one of seven currently known human oncoviruses. It is suspected to cause the majority of cases of Merkel cell carcinoma, a rare but aggressive form of skin cancer. Approximately 80% of Merkel cell carcinoma (MCC) tumors have been found to be infected with MCV. MCV appears to be a common—if not universal—infection of older children and adults. It is found in respiratory secretions, suggesting that it might be transmitted via a respiratory route. However, it has also been found elsewhere, such as in shedded healthy skin and gastrointestinal tract tissues, thus its precise mode of transmission remains unknown. In addition, recent studies suggest that this virus may latently infect the human sera and peripheral blood mononuclear cells.

Anthony (Tony) Charles Minson, PhD, FMedSci is a British virologist known for his work on the biology of herpesviruses, and a university administrator. He was the Senior Pro-Vice-Chancellor of the University of Cambridge from 2003 to 2009. He is an emeritus professor of virology at the university's Department of Pathology and an emeritus fellow of Wolfson College.

A neutralizing antibody (NAb) is an antibody that defends a cell from a pathogen or infectious particle by neutralizing any effect it has biologically. Neutralization renders the particle no longer infectious or pathogenic. Neutralizing antibodies are part of the humoral response of the adaptive immune system against viruses, bacteria and microbial toxin. By binding specifically to surface structures (antigen) on an infectious particle, neutralizing antibodies prevent the particle from interacting with its host cells it might infect and destroy.

<span class="mw-page-title-main">Adolfo García-Sastre</span> Spanish and American academic

Adolfo García-Sastre,(born in Burgos, 10 October 1964) is a Spanish professor of Medicine and Microbiology and co-director of the Global Health & Emerging Pathogens Institute at the Icahn School of Medicine at Mount Sinai in New York City. His research into the biology of influenza viruses has been at the forefront of medical advances in epidemiology.

The species Sudan ebolavirus is a virological taxon included in the genus Ebolavirus, family Filoviridae, order Mononegavirales. The species has a single virus member, Sudan virus (SUDV). The members of the species are called Sudan ebolaviruses. It was discovered in 1977 and causes Ebola clinically indistinguishable from the ebola Zaire strain, but is less transmissible than it. Unlike with ebola Zaire there is no vaccine available.

<span class="mw-page-title-main">Marburg virus</span> Species of filamentous virus responsible for hemorrhagic fever

Marburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. The World Health Organization (WHO) rates it as a Risk Group 4 Pathogen. In the United States, the National Institute of Allergy and Infectious Diseases ranks it as a Category A Priority Pathogen and the Centers for Disease Control and Prevention lists it as a Category A Bioterrorism Agent. It is also listed as a biological agent for export control by the Australia Group.

Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Examples of particular herpes research include drug development, vaccines and genome editing. HSV-1 and HSV-2 are commonly thought of as oral and genital herpes respectively, but other members in the herpes family include chickenpox (varicella/zoster), cytomegalovirus, and Epstein-Barr virus. There are many more virus members that infect animals other than humans, some of which cause disease in companion animals or have economic impacts in the agriculture industry.

M. Juliana “Julie” McElrath is a senior vice president and director of the vaccine and infection disease division at Fred Hutchinson Cancer Research Center and the principal investigator of the HIV Vaccine Trials Network Laboratory Center in Seattle, Washington. She is also a professor at the University of Washington.

mRNA vaccine Type of vaccine

An mRNAvaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules of antigen-encoding mRNA into immune cells, which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen or by a cancer cell. These protein molecules stimulate an adaptive immune response that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is delivered by a co-formulation of the RNA encapsulated in lipid nanoparticles that protect the RNA strands and help their absorption into the cells.

<span class="mw-page-title-main">Viral vector vaccine</span> Type of vaccine

A viral vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA coding for a desired protein, or antigen, to elicit an immune response. As of April 2021, six viral vector vaccines, four COVID-19 vaccines and two Ebola vaccines, have been authorized for use in humans.

A genetic vaccine is a vaccine that contains nucleic acids such as DNA or RNA that lead to protein biosynthesis of antigens within a cell. Genetic vaccines thus include DNA vaccines, RNA vaccines and viral vector vaccines.

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