Finegoldia

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Finegoldia
Scientific classification
Domain:
Bacteria
Phylum:
Bacillota
Class:
Clostridia
Order:
Tissierellales
Family:
Peptoniphilaceae
Genus:
Finegoldia

Murdoch & Shah 2000
Type species
Finegoldia magna
(Prévot 1933) Murdoch & Shah 2000
Species
  • "F. dalianensis"
  • F. magna

Finegoldia is a genus of Gram-positive bacteria. They are anaerobic cocci of the class Clostridia, with Finegoldia magna being the type species. [1] F. magna was formerly known, along with several other Gram-positive anaerobic cocci (GPACs), as Peptostreptococcus magnus, but was moved into its own genus in 1999. [2] [3] The name is in honor of Sydney M. Finegold, an American microbiologist, while magna is Latin for large. [1] It is an opportunistic human pathogen that normally colonizes skin and mucous membranes. [4] It is often seen in biofilms on chronic ulcers such as in diabetic foot or decubitus ulcers. [3] Most surveys have found it to be susceptible to penicillins, carbapenems and metronidazole, though resistant strains have been identified. [5] Resistance to clindamycin is common and has been seen in over 10% of isolates in the US. [3] [6] One review stated that "the combination of diminished antimicrobial susceptibility, its prevalence, and the described virulence factors gives F. magna a special position among the GPAC." [5]

See also

References

  1. 1 2 A.C. Parte; et al. "Finegoldia". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2023-09-09.
  2. ↑ Murdoch, D. A; Shah, H. N (1999-10-01). "Reclassification of Peptostreptococcus magnus (Prevot 1933) Holdeman and Moore 1972 as Finegoldia magna comb. nov. and Peptostreptococcus micros (Prevot 1933) Smith 1957 as Micromonas micros comb. nov". Anaerobe. 5 (5): 555–559. doi:10.1006/anae.1999.0197.
  3. 1 2 3 John e. Bennett, MD; Raphael Dolin, MD; Martin j. Blaser, MD (2014-08-28). "Anaerobic Cocci and Anaerobic Gram-Positive Nonsporulating Bacilli". Mandell, Douglas, and Bennett's principles and practice of infectious diseases. ISBN   978-1-4557-4801-3.
  4. ↑ de Moreuil, Claire; Héry-Arnaud, Geneviève; David, Charles-Henri; Provost, Bastien; Mondine, Philippe; Alavi, Zarrin; de Saint Martin, Luc; Bezon, Eric; Berre, Rozenn Le (2015-04-01). "Finegoldia magna, not a well-known infectious agent of bacteriemic post-sternotomy mediastinitis". Anaerobe. 32: 32–33. doi:10.1016/j.anaerobe.2014.11.012. PMID   25448620.
  5. 1 2 Veloo, A. C. M.; Welling, G. W.; Degener, J. E. (2011-03-01). "Antimicrobial Susceptibility of Clinically Relevant Gram-Positive Anaerobic Cocci Collected over a Three-Year Period in the Netherlands". Antimicrobial Agents and Chemotherapy. 55 (3): 1199–1203. doi:10.1128/AAC.01771-09. ISSN   0066-4804. PMC   3067104 . PMID   21189338.
  6. ↑ Brazier, J. S.; Hall, V.; Morris, T. E.; Gal, M.; Duerden, B. I. (2003-08-01). "Antibiotic susceptibilities of Gram-positive anaerobic cocci: results of a sentinel study in England and Wales". Journal of Antimicrobial Chemotherapy. 52 (2): 224–228. doi: 10.1093/jac/dkg316 . ISSN   0305-7453. PMID   12837734.
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