Clostridioides

Clostridioides
SE micrograph of Clostridioides difficile colonies from a stool sample
Scientific classification
Domain:	Bacteria
Phylum:	Bacillota
Class:	Clostridia
Order:	Eubacteriales
Family:	Peptostreptococcaceae
Genus:	Clostridioides Lawson and Rainey 2016 [1]
Type species
Clostridioides difficile (Hall & O'Toole 1935) Lawson et al. 2016
Species
C. difficile
Synonyms
"Peptoclostridium" Yutin & Galperin 2013 non Galperin et al. 2016 non Donker 1926

Clostridioides is a genus of Gram-positive bacteria, which includes Clostridioides difficile , a human pathogen causing an infectious diarrhea.

Taxonomy

The genus Clostridioides was created to describe a few species formerly in the genus Clostridium which have been shown to be their own genetically distinct genus using 16S rRNA gene sequencing analysis. ^[2] However, both names are still in use and valid under the International Code of Nomenclature of Prokaryotes. ^[3] Since C. mangenotii was further separated into a distinct genus in 2024, ^[4] Clostridioides is a monotypic genus.

Description

They are obligate anaerobes capable of producing endospores. The normal, reproducing cells of Clostridioides, called the vegetative form, are rod-shaped, which gives them their name, from the Greek κλωστήρ or spindle. Clostridioides endospores, like Clostridium endospores, have a distinct bowling pin or bottle shape, distinguishing them from other bacterial endospores, which are usually ovoid in shape.^{[ citation needed ]}

See also

• List of bacterial orders
• List of bacteria genera

References

1. A.C. Parte; et al. "Clostridioides". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2023-09-09.
2. Lawson, Paul A.; Citron, Diane M.; Tyrrell, Kerin L.; Finegold, Sydney M. (August 2016). "Reclassification of Clostridium difficile as Clostridioides difficile (Hall and O'Toole 1935) Prévot 1938". Anaerobe. 40: 95–99. doi:10.1016/j.anaerobe.2016.06.008. PMID   27370902.
3. Oren, Aharon; Rupnik, Maja (August 2018). "Clostridium difficile and Clostridioides difficile: Two validly published and correct names". Anaerobe. 52: 125–126. doi:10.1016/j.anaerobe.2018.07.005. PMID   30031828. S2CID   51707574.
4. Bello, Sarah; McQuay, Sarah; Rudra, Bashudev; Gupta, Radhey (2024). "Robust demarcation of the family Peptostreptococcaceae and its main genera based on phylogenomic studies and taxon-specific molecular markers". International Journal of Systematic and Evolutionary Microbiology. 74 (2). doi: 10.1099/ijsem.0.006247 . PMID   38319314.