Rhinosporidiosis

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Rhinosporidiosis
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Rhinosporidiosis in oropharynx
Specialty Infectious disease

Rhinosporidiosis is an infection caused by Rhinosporidium seeberi . [1] [2]

Contents

Classification

This organism was previously considered to be a fungus, and rhinosporidiosis is classified as a fungal disease under ICD-10. It is now considered to be a protist [3] classified under Mesomycetozoea. [4]

Authors of detailed studies have revealed superficial similarities between Dermocystidium and Rhinosporidium when using light microscopy, but substantial morphological differences between the groups exist. [5]

There is some evidence that DNA extracted from purified uncontaminated round bodies (Rhinosporidium seeberi) is of cyanobacterial origin. [6]

Pathophysiology

Rhinosporidiosis is a granulomatous disease affecting the mucous membrane of nasopharynx, oropharynx, conjunctiva, rectum and external genitalia. Though the floor of the nose and inferior turbinate are the most common sites, the lesions may appear elsewhere too. Traumatic inoculation from one site to others is common. Laryngeal rhinosporidiosis, [7] too, has been described and may be due to inoculation from the nose during endotracheal intubation. After inoculation, the organism replicates locally, resulting in hyperplasia of host tissue and localised immune response.[ citation needed ]

Diagnosis

Treatment

Epidemiology

Disease endemic in Chhattisgarh South India, Sri Lanka, South America and Africa. It is presumed to be transmitted by exposure to the pathogen when taking a bath in stagnant water pools where animals also bathe.It is also common in South Asian countries.[ citation needed ]

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References

  1. Arseculeratne SN (2002). "Recent advances in rhinosporidiosis and rhinosporidium seeberi". Indian J Med Microbiol. 20 (3): 119–31. doi:10.1016/S0255-0857(21)03243-6. PMID   17657050.
  2. Arseculeratne SN (April 2005). "Rhinosporidiosis: what is the cause?". Curr. Opin. Infect. Dis. 18 (2): 113–8. doi:10.1097/01.qco.0000160898.82115.e8. PMID   15735413. S2CID   38343304.
  3. Morelli L, Polce M, Piscioli F, et al. (2006). "Human nasal rhinosporidiosis: an Italian case report". Diagn Pathol. 1 (1): 25. doi: 10.1186/1746-1596-1-25 . PMC   1560165 . PMID   16945122.
  4. "Rhinosporidiosis". Archived from the original on 2021-09-23. Retrieved 2008-07-23.
  5. Pekkarinen, Low, Murphy, Ragan and Dykova. 2003. Phylogenetic position and ultrastructure of two Dermocystidium species are(Ichthyosporea) from the common perch (Perca fluviatilis) Archived 2007-10-10 at the Wayback Machine . Acta Protozoologica Vol. 42:287-307
  6. Dhaulakhandi, Ahluwalia, Ravi and Garg. 2006. Detection of 16S rRNA gene in round bodies isolated from polyps of rhinosporidiosis. Infection, Genetics and Evolution Vol. 6:331-336
  7. Ajit Daharwal, Hansa Banjara, Digvijay Singh, Anuj Gupta, Surjeet Singh. 2011. A rare case of laryngeal rhinosporidiosis. J Laryngol Voice 2011;1:30-2