N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. N-acetyltransferases are cytosolic enzymes found in the liver and many tissues of most mammalian species, except the dog and fox, which cannot acetylate xenobiotics.
Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The gene is translated into a 23 kDa large enzyme. It is well conserved through evolution and the human form of the protein is 80 percent identical to sheep and rat AANAT. It is an acetyl-CoA-dependent enzyme of the GCN5-related family of N-acetyltransferases (GNATs). It may contribute to multifactorial genetic diseases such as altered behavior in sleep/wake cycle and research is on-going with the aim of developing drugs that regulate AANAT function.
N-acetyltransferase 2 , also known as NAT2, is an enzyme which in humans is encoded by the NAT2 gene.
In enzymology, a 10-hydroxytaxane O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a 1-alkylglycerophosphocholine O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an alcohol O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an alkylglycerophosphate 2-O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an aromatic-hydroxylamine O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an arylamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a cortisol O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a D-amino-acid N-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a deacetylvindoline O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a homoserine O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a maltose O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction
In enzymology, a N-acetylneuraminate 4-O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a N-acetylneuraminate 7-O(or 9-O)-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a peptide alpha-N-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a serine O-acetyltransferase is an enzyme that catalyzes the chemical reaction
N-acetyltransferase 1 is a protein that in humans is encoded by the NAT1 gene.
