National Bio and Agro-Defense Facility

Last updated
National Bio and Agro-Defense Facility
National Bio and Agro-Defense Facility Logo.png
NBAF logo
NBAF new 2021.jpg
Front of the NBAF
Established2015
Laboratory type
Biosafety level 4 research laboratory
Research typeScientific research and biodefense
Budget US$1.25 billion (2021)
Field of research
Human, zoonotic, and foreign animal diseases
Director Alfonso Clavijo
Staff 250–350
Location Manhattan, Kansas, U.S.
39°12′11″N96°35′03″W / 39.20306°N 96.58417°W / 39.20306; -96.58417 Coordinates: 39°12′11″N96°35′03″W / 39.20306°N 96.58417°W / 39.20306; -96.58417
66506
Campus 574,000 square feet (53,300 m2)
NicknameNBAF
Affiliations Kansas State University
Operating agency
United States Department of Agriculture
Website USDA website
USA Kansas location map.svg
Red pog.svg
NBAF
Location within the State of Kansas

The National Bio and Agro-Defense Facility (NBAF) is a biosafety level 4 research laboratory in Manhattan, Kansas, operated by the United States Department of Agriculture. Slated to open in Summer 2022, the facility is designed to combat biological threats involving human, zoonotic, and foreign animal diseases. The NBAF will be replacing the aging Plum Island Animal Disease Center (PIADC) on Plum Island, New York. [1] The primary research tenants of the facility will be the Agriculture Research Service (USDA-ARS) and Animal Plant Health Inspection Service, Veterinary Services (USDA-APHIS-VS). [1] [2] Construction on the 574,000-square-foot (53,300 m2) facility officially began in May 2015, and was scheduled to be completed by May 2021. The ongoing COVID-19 pandemic, however, has delayed scheduled commissioning to October 2021, followed by further delays to Spring, and, subsequently, Summer 2022. [1] [3] [4] [5] Operations will be fully transferred from the Plum Island facility by 2023. [6] When fully operational, the facility will employ between 250 and 350 people. [1] [2] The facility is a constituent member of the Biosafety Level 4 Zoonotic Laboratory Network, and is currently led by Alfonso Clavijo.

Contents

Background

The NBAF was initially proposed because the prior facility on Plum Island was considered inadequate by the Department of Homeland Security, citing its size, and lack of Biosafety Level 4 (BSL-4) capabilities. [7]

The new facility will research and develop countermeasures to combat high-consequence biological threats involving human, zoonotic (i.e., transmitted from animals to humans), and foreign animal diseases. [2] Included among the diseases to be studied at the research lab are foot-and-mouth disease, classical swine fever, African swine fever and contagious bovine pleuropneumonia. [2] Approximately 10% of the facility will be used for BSL-4 level research. [1]

Site selection

DHS decided to locate the NBAF in Manhattan, Kansas, after a multi-year process. Out of 29 original sites considered in 2006, the agency selected six finalists in 2008:[ citation needed ]

Before the selection of the site, several rural advocacy groups, such as the National Grange, spoke out against the idea of locating the facility on the mainland. [8] In addition, groups formed in Manhattan; Athens, Georgia; and Butner, North Carolina to oppose the laboratory's proposed location in those cities. [9] [10]

By memo dated December 4, 2008, the Department of Homeland Security named the Kansas site as the preferred location for the NBAF. On January 16, 2009, the record of decision was published in the Federal Register . [7]

After the Manhattan location was finalized in 2009, the Government Accountability Office questioned the choice of location in a July 2010 draft report, because it is located on the mainland U.S. unlike the current Plum Island facility. [11] This led to a further "site-specific" study of the facility's safety, issued by DHS in 2012. [12]

Risk assessments

Plum Island is the only research facility currently studying foot-and-mouth disease (FMD) in the U.S. In 2008, the Government Accountability Office (GAO) was asked to evaluate the evidence DHS used to support its determinations that FMD work can be done safely on the U.S. mainland, whether an island location provides any additional protection over and above that provided by modern high containment laboratories on the mainland, and the economic consequences of an FMD outbreak on the U.S. mainland.[ citation needed ]

Because of concerns raised by the GAO in 2010, Congress instructed DHS to complete a "site-specific biosafety and biosecurity risk assessment." [11] [9] It also directed the National Academy of Sciences to appoint a committee of the National Research Council (NRC) to conduct an independent evaluation of this site-specific risk analysis to determine its adequacy and validity. Congress would not release construction funds until these were completed and evaluated.

DHS completed the requisite site-specific risk analysis (SSRA) in March 2012, and the NRC committee issued its evaluation of the SSRA in June 2012. [12] [13]

Site construction

NBAF construction site in Manhattan in 2013 NBAF.JPG
NBAF construction site in Manhattan in 2013

The facility is under construction. Preliminary clearing and grading of the proposed site began in 2010, construction on the site's power plant began in 2013, and construction of the lab began in 2015.

On January 2, 2013, the Department of Homeland Security accepted a transfer of land from the State of Kansas for the site of the facility. In March 2013, a contract was awarded for the construction of a central utility plant for the NBAF. [4] An official groundbreaking ceremony for construction of the power plant was held on May 28, 2013. [14]

The federal government budgeted $440 million for construction and related work on the NBAF under the Consolidated Appropriations Act of 2014, signed into law on January 17, 2014. President Barack Obama included an additional $300 million for construction in his proposed 2015 budget, constituting the final installment of federal construction spending for the facility. This funding was secured when President Obama signed into law the Department of Homeland Security Appropriations Act, 2015, on March 3, 2015.

A groundbreaking ceremony for construction on the full facility was held on May 27, 2015. [3] [15] It was attended by Kansas Senator Pat Roberts, Kansas Governor Sam Brownback, U.S. Secretary of Agriculture Tom Vilsack, and Homeland Security Secretary Jeh Johnson. [3]

In 2019 the Department of Homeland Security shed its interest in the project, and agreed to transfer operating responsibility of the facility once completed to the Department of Agriculture. DHS will remain in charge of the remainder of construction. [16]

Related Research Articles

<span class="mw-page-title-main">Kansas State University</span> Public university in Manhattan, Kansas, United States

Kansas State University is a public land-grant research university with its main campus in Manhattan, Kansas, United States. It was opened as the state's land-grant college in 1863 and was the first public institution of higher learning in the state of Kansas. It had a record high enrollment of 24,766 students for the Fall 2014 semester.

<span class="mw-page-title-main">United States Department of Homeland Security</span> United States federal department

The United States Department of Homeland Security (DHS) is the U.S. federal executive department responsible for public security, roughly comparable to the interior or home ministries of other countries. Its stated missions involve anti-terrorism, border security, immigration and customs, cyber security, and disaster prevention and management.

<span class="mw-page-title-main">Biosafety level</span> Level of the biocontainment precautions required to isolate dangerous biological agents

A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. In the European Union, the same biosafety levels are defined in a directive. In Canada the four levels are known as Containment Levels. Facilities with these designations are also sometimes given as P1 through P4, as in the term P3 laboratory.

<span class="mw-page-title-main">Flora, Mississippi</span> Town in Mississippi, United States

Flora is a town in Madison County, Mississippi, United States. The population was 1,886 at the 2010 census. It is part of the Jackson Metropolitan Statistical Area.

<span class="mw-page-title-main">Plum Island Animal Disease Center</span> American research facility

Plum Island Animal Disease Center (PIADC) is a United States federal research facility dedicated to the study of foreign animal diseases of livestock. It is part of the Department of Homeland Security Directorate for Science and Technology, and operates as a partnership with the U.S. Department of Agriculture. The facility's director is Dr. Larry Barrett.

<span class="mw-page-title-main">Plum Island (New York)</span> Island in New York, United States

Plum Island is an island in the town of Southold in Suffolk County, New York. The island is situated in Gardiners Bay, east of Orient Point, off the eastern end of the North Fork coast of Long Island. It is about 3 miles (4.8 km) long and 1 mile (1.6 km) wide at its widest point.

The National Microbiology Laboratory (NML) is part of the Public Health Agency of Canada (PHAC), the agency of the Government of Canada that is responsible for public health, health emergency preparedness and response, and infectious and chronic disease control and prevention.

<span class="mw-page-title-main">Fort Terry</span>

Fort Terry was a coastal fortification on Plum Island, a small island just off Orient Point, New York, United States. This strategic position afforded it a commanding view over the Atlantic entrance to the commercially vital Long Island Sound. It was established in 1897 and used intermittently through the end of World War II. In 1952, it became a military animal and biological warfare (BW) research facility, moving to civilian control in 1954 as the Plum Island Animal Disease Center. However, the biological warfare mission continued under civilian control until 1969, when the US ended offensive BW research. The island is now being considered for sale or conversion to a wildlife refuge. Fort Terry was listed on the National Register of Historic Places in 2021.

The National Biodefense Analysis and Countermeasures Center (NBACC) is a government biodefense research laboratory created by the U.S. Department of Homeland Security (DHS) and located at the sprawling biodefense campus at Fort Detrick in Frederick, MD, USA. The NBACC is the principal U.S. biodefense research institution engaged in laboratory-based threat assessment and bioforensics. NBACC is an important part of the National Interagency Biodefense Campus (NIBC) also located at Fort Detrick for the US Army, National Institutes of Health and the US Department of Agriculture.

<span class="mw-page-title-main">DHS Science and Technology Directorate</span>

The Science and Technology Directorate (S&T) is a component within the United States Department of Homeland Security. DHS-S&T serves as the research and development arm of the Department as it fulfills its national security mission.

<span class="mw-page-title-main">DHS Chemical and Biological Defense Division</span>

The Chemical and Biological Defense Division (CBD) is a division of the Science and Technology Directorate of the United States Department of Homeland Security. Within the Homeland Security Advanced Research Projects Agency, CBD develops technologies to increase the United States's preparedness and protect key national infrastructure against chemical, biological, and agricultural threats and disasters through improved threat awareness and advanced surveillance, detection, and protective countermeasures.

<span class="mw-page-title-main">Foot-and-mouth disease</span> Medical condition

Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, followed by blisters inside the mouth and near the hoof that may rupture and cause lameness.

Homeland Security Centers of Excellence (HS-Centers) are sponsored by the U.S. Department of Homeland Security. These Centers develop technology and training for police and domestic military units. The Centers were created under the Homeland Security Act in 2002 in order to establish a coordinated, university-based system to increase domestic security measures.

<span class="mw-page-title-main">Oregon PHL/DEQ Laboratories</span>

The Oregon PHL/DEQ Laboratories are the Oregon Department of Environmental Quality (DEQ) and Oregon Department of Human Services (DHS) laboratories located in a single building in Hillsboro, Oregon, United States. DHS operates the Oregon State Public Health Laboratory (OSPHL), and the DEQ operates their Laboratory and Environmental Assessment Division at the site. The laboratories previously were located at Portland State University, moving to the new location near Cornelius Pass Road and the Sunset Highway in northeast Hillsboro in 2007.

National Urban Security Technology Laboratory is a United States government-owned, government-operated laboratory, part of the Department of Homeland Security (DHS) Science & Technology Directorate. It is located in the Federal Office Building at 201 Varick Street in the Hudson Square neighborhood, Manhattan, New York.

Biosecurity in the United States is governed by the Bureau of Western Hemisphere Affairs, which is part of the US Department of State. It obtains guidance and advice on specific matters relating to biosecurity from various other government agencies.

<span class="mw-page-title-main">Texas Energy Engineers</span>

Texas Energy Engineers, Inc., dba ccrd partners, is a professional engineering firm headquartered in Houston, TX (USA).

A Foreign animal disease (FAD) is an animal disease or pest, whether terrestrial or aquatic, not known to exist in the United States or its territories. When these diseases can significantly affect human health or animal production and when there is significant economic cost for disease control and eradication efforts, they are considered a threat to the United States. Another term gaining preference to be used is Transboundary Animal Disease (TAD), which is defined as those epidemic diseases which are highly contagious or transmissible and have the potential for very rapid spread, irrespective of national borders, causing serious socio-economic and possibly public health consequences. An Emerging Animal Disease "may be defined as any terrestrial animal, aquatic animal, or zoonotic disease not yet known or characterized, or any known or characterized terrestrial animal or aquatic animal disease in the United States or its territories that changes or mutates in pathogenicity, communicability, or zoonotic potential to become a threat to terrestrial animals, aquatic animals, or humans."

The Biosafety Level 4 Zoonotic Laboratory Network is an international consortium of Biosafety Level 4 research laboratories. Its members are

References

  1. 1 2 3 4 5 "National Bio and Agro-Defense Facility". U.S. Department of Homeland Security. Archived from the original on 2013-05-03. Retrieved 2013-04-24.
  2. 1 2 3 4 "Facility Research & Staffing". U.S. Department of Homeland Security. 6 July 2009. Retrieved 2010-07-21.
  3. 1 2 3 Viviani, Nick; Thompson, Monty (May 27, 2015), Hundreds Turn Out For NBAF Groundbreaking, wibw.com, retrieved June 9, 2015
  4. 1 2 Carpenter, Tim (April 10, 2013). "Obama Budget Offers $714M for NBAF". The Topeka Capital-Journal. Retrieved 2013-04-24.
  5. "NBAF delays full open to summer 2022 amid technology upgrades". News Radio KMAN. 2021-11-05. Retrieved 2022-03-19.
  6. Lysen, Dylan (February 5, 2017). "On Track: NBAF construction 'on time, budget' according to officials". The Manhattan Mercury.{{cite journal}}: Cite journal requires |journal= (help)
  7. 1 2 Federal Register: ROD for NBAF (English), U.S. Department of Homeland Security, January 16, 2009, retrieved 2010-07-21
  8. "National Grange Opposes Mainland Research Facility". Archived from the original on 2008-10-25. Retrieved 2008-06-12.
  9. 1 2 "Dangerous Animal Virus on US Mainland?". The Associated Press. 2008-04-11. Retrieved 2010-07-21.
  10. No NBAF in Kansas
  11. 1 2 Leonnig, Carol D. (2009-07-27). "Infectious diseases study site questioned: Tornado Alley may not be safe, GAO says". Washington Post. Retrieved 2010-07-21.
  12. 1 2 "DHS Issues Updated Site-Specific Risk Assessment for Proposed National Bio and Agro-Defense Facility (NBAF)" (Press release). U.S. Department of Homeland Security. March 2, 2012. Retrieved 2013-04-24.
  13. "Officials press feds for NBAF". Lawrence Journal-World. 2012-06-15. Retrieved 2013-05-14.
  14. Milburn, John (May 28, 2013). "Kansas officials break ground on NBAF project". Associated Press. Retrieved 2013-05-28.{{cite journal}}: Cite journal requires |journal= (help)
  15. Williams, Mara Rose (May 30, 2015). "Foreseeing an economic boom, Manhattan, Kan., opens its arms to new lab". Kansas City Star. Retrieved 2015-06-09.
  16. "News Release: Signing Ceremony Sets Terms of NBAF Transfer From Homeland Security to USDA". www.newswise.com. Retrieved 2021-07-15.