Panadol night is a GlaxoSmithKline painkiller intended for use at night. It consists of 500 milligrams of paracetamol, 25 milligrams of diphenhydramine hydrochloride (a sedating antihistamine) and other "non-hazardous ingredients" [1] It is sold in Australia, Cyprus United Kingdom, Ireland, New Zealand and the Middle East. It became available as an over the counter medication in the UK in 1996.
Panadol night tablets contain two active ingredients, paracetamol and diphenhydramine. Although paracetamol has been widely used for more than a hundred years, scientists still don't fully understand its bio-mechanisms. The main belief is that it reduces the production of prostaglandins in the brain and spinal cord. [2] [3] Diphenhydramine is a sedating H1 antagonist. Diphenhydramine works by blocking the effects of histamine and causes drowsiness. The combination of the active ingredients in Panadol night can be used to relieve mild to moderate pain such as headaches, backache or period pain that is causing difficulty getting to sleep. [4]
Paracetamol is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over the counter medication and common brand names include Tylenol and Panadol.
Horlicks is a sweet malted milk hot drink powder developed by founders James and William Horlick. It was first sold as "Horlick's Infant and Invalids Food", soon adding "aged and travellers" to their label. In the early 20th century, it was sold as a powdered meal replacement drink mix.
Dihydrocodeine is a semi-synthetic opioid analgesic prescribed for pain or severe dyspnea, or as an antitussive, either alone or compounded with paracetamol (acetaminophen) or aspirin. It was developed in Germany in 1908 and first marketed in 1911.
Excedrin is an over-the-counter headache pain reliever, typically in the form of tablets or caplets. It contains paracetamol (acetaminophen), aspirin, and caffeine. It was manufactured by Bristol-Myers Squibb until it was purchased by Novartis in July 2005 along with other products from BMS's over-the-counter business. As of March 2015, GSK holds majority ownership of Excedrin through a joint venture transaction with Novartis. On 18 July 2022, GSK spun off its consumer healthcare business to Haleon.
Doxylamine, sold under the brand name Unisom among others, is an antihistamine medication which is used in the treatment of insomnia and allergies. It is also used to treat morning sickness in pregnant women in combination with pyridoxine (vitamin B6). Doxylamine is available over-the-counter, and is used in nighttime cold medicines, such as NyQuil, as well as in pain medications containing acetaminophen and codeine, to help with sleep. The medication is taken by mouth.
Methocarbamol, sold under the brand name Robaxin among others, is a medication used for short-term musculoskeletal pain. It may be used together with rest, physical therapy, and pain medication. It is less preferred in low back pain. It has limited use for rheumatoid arthritis and cerebral palsy. Effects generally begin within half an hour. It is taken by mouth or injection into a vein.
Goody's Powder, also called Goody's Headache Powders, is an over-the-counter aspirin/paracetamol/caffeine–based pain reliever, in single-dose powder form, which is marketed and sold by Prestige Brands. The powder delivery saves the time needed for the patient's digestive system to break down a tablet or capsule, ostensibly causing the medication to work faster. Goody's Extra Strength Powder consists of aspirin, caffeine, and paracetamol (acetaminophen) in a formula identical to that of Excedrin, a product of Novartis, but in the no-digestion-needed powder form.
Dyclonine (Dyclocaine) is an oral anaesthetic that is the active ingredient of Sucrets, an over-the-counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.
Sominex is the trademarked name for several over the counter sleep aids.
Propyphenazone/paracetamol/caffeine is an analgesic combination indicated for the management of headache. It contains the analgesics propyphenazone and paracetamol and the stimulant caffeine.
Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking histamine H1 receptors.
Cervarix is a vaccine against certain types of cancer-causing human papillomavirus (HPV).
Sensodyne is a brand name of toothpaste and mouthwash targeted at people with sensitive teeth. Sensodyne is owned by Haleon and is marketed under the name Shumitect in Japan.
A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form. Terms like "combination drug" or "combination drug product" can be common shorthand for an FDC product, although the latter is more precise if in fact referring to a mass-produced product having a predetermined combination of drugs and respective dosages. And it should also be distinguished from the term "combination product" in medical contexts, which without further specification can refer to products that combine different types of medical products—such as device/drug combinations as opposed to drug/drug combinations. When a combination drug product is a "pill", then it may also be a kind of "polypill" or combopill.
Solpadeine is the brand name of a range of analgesic medication containing various amounts of paracetamol, ibuprofen, caffeine and codeine, made by Omega Pharma. The range was previously made by GlaxoSmithKline, which sold its portfolio of over-the-counter drugs to Omega Pharma in 2012.
Hydrocodone/paracetamol is the combination of the pain medications hydrocodone and paracetamol (acetaminophen). It is used to treat moderate to severe pain. It is taken by mouth. Recreational use is common in the United States.
Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, Papaver somniferum. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe, it is not recommended as a cough medicine in those under 12 years of age. It is generally taken by mouth. It typically starts working after half an hour, with maximum effect at two hours. Its effects last for about four to six hours. Codeine exhibits abuse potential similar to other opioid medications, including a risk of habituation and overdose.
Nurofen is a brand name range of pain-relief medication containing ibuprofen made by the British multinational Reckitt. Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. The brand is primarily marketed and sold in the United Kingdom, other parts of Europe, South Africa, Australia and New Zealand. In 2016 it was the biggest selling branded over-the-counter medication sold in Great Britain, with sales of £116.8 million.
Haleon plc is a British multinational consumer healthcare company with headquarters in Weybridge, England. It is one of the largest consumer healthcare businesses in the world, with brands including Sensodyne toothpaste, Panadol and Advil painkillers and Centrum vitamins. The company is a global leader in over the counter medicines with a 7.3 percent market share.
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