Shionone synthase

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Shionone synthase
Identifiers
EC no. 5.4.99.46
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

Shionone synthase (EC 5.4.99.46) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, shionone-forming). [1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene shionone

The enzyme gives traces of four other triterpenoids

References

  1. Sawai S, Uchiyama H, Mizuno S, Aoki T, Akashi T, Ayabe S, Takahashi T (April 2011). "Molecular characterization of an oxidosqualene cyclase that yields shionone, a unique tetracyclic triterpene ketone of Aster tataricus". FEBS Letters. 585 (7): 1031–6. Bibcode:2011FEBSL.585.1031S. doi: 10.1016/j.febslet.2011.02.037 . PMID   21377465.