Suptavumab

Last updated

Suptavumab
Monoclonal antibody
Type ?
Source Human
Target respiratory syncytial virus fusion protein
Clinical data
Other namesREGN2222
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
Formula C6502H10038N1726O2020S42
Molar mass 146054.41 g·mol−1

Suptavumab (INN; [1] development code (REGN2222) is a humanized monoclonal antibody designed for the prevention of medically attended lower respiratory tract disease due to respiratory syncytial virus. [2]

This experimental drug candidate was being developed by Regeneron Pharmaceuticals Inc until it was discontinued after unsuccessful Phase III clinical trials. [3] [4]

References

  1. World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 115" (PDF). WHO Drug Information. 30 (2).
  2. Sevendal AT, Hurley S, Bartlett AW, Rawlinson W, Walker GJ (September 2024). "Systematic Review of the Efficacy and Safety of RSV-Specific Monoclonal Antibodies and Antivirals in Development". Reviews in Medical Virology. 34 (5) e2576. doi:10.1002/rmv.2576. PMID   39209729.
  3. Statement On A Nonproprietary Name Adopted By The USAN Council - Suptavumab, American Medical Association.
  4. "Regeneron to Discontinue Development of Suptavumab for Respiratory Syncytial Virus" (Press release). Regeneron. August 14, 2017.