thetin-homocysteine S-methyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.1.1.3 | ||||||||
CAS no. | 9029-76-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a thetin-homocysteine S-methyltransferase (EC 2.1.1.3) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are dimethylsulfonioacetic acid and L-homocysteine, whereas its two products are S-methylthioglycolic acid and L-methionine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is dimethylsulfonioacetic acid:L-homocysteine S-methyltransferase. Other names in common use include dimethylthetin-homocysteine methyltransferase, and thetin-homocysteine methylpherase.
S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952.
Histone-arginine N-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:histone-arginine Nomega-methyltransferase. This enzyme catalyses the following chemical reaction
In enzymology, a 5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase is an enzyme that catalyzes the chemical reaction
In the field of enzymology, a betaine-homocysteine S-methyltransferase also known as betaine-homocysteine methyltransferase (BHMT) is a zinc metallo-enzyme that catalyzes the transfer of a methyl group from trimethylglycine and a hydrogen ion from homocysteine to produce dimethylglycine and methionine respectively:
In enzymology, a [cytochrome c]-lysine N-methyltransferase (EC 2.1.1.59) is an enzyme that catalyzes the chemical reaction
In enzymology, a glycine N-methyltransferase is an enzyme that catalyzes the chemical reaction
Guanidinoacetate N-methyltransferase is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3.
In enzymology, a homocysteine S-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an isobutyraldoxime O-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a magnesium protoporphyrin IX methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a methionine S-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a phosphatidyl-N-methylethanolamine N-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a thiol S-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA (adenine-N1-)-methyltransferase (EC 2.1.1.36) is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA (cytosine-5-)-methyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA (guanine-N1-)-methyltransferase (EC 2.1.1.31) is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA (guanine-N2-)-methyltransferase (EC 2.1.1.32) is an enzyme that catalyzes the chemical reaction
In enzymology, a tRNA (guanine-N7-)-methyltransferase (EC 2.1.1.33) is an enzyme that catalyzes the chemical reaction
In enzymology, a tyramine N-methyltransferase is an enzyme that catalyzes the chemical reaction
Arsenite methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:arsenite As-methyltransferase. This enzyme catalyses the following chemical reaction