Radiodensity

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Radiodensity (or radiopacity) is opacity to the radio wave and X-ray portion of the electromagnetic spectrum: that is, the relative inability of those kinds of electromagnetic radiation to pass through a particular material. Radiolucency or hypodensity indicates greater passage (greater transradiancy) to X-ray photons [1] and is the analogue of transparency and translucency with visible light. Materials that inhibit the passage of electromagnetic radiation are called radiodense or radiopaque, while those that allow radiation to pass more freely are referred to as radiolucent. Radiopaque volumes of material have white appearance on radiographs, compared with the relatively darker appearance of radiolucent volumes. For example, on typical radiographs, bones look white or light gray (radiopaque), whereas muscle and skin look black or dark gray, being mostly invisible (radiolucent).

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Though the term radiodensity is more commonly used in the context of qualitative comparison, radiodensity can also be quantified according to the Hounsfield scale, a principle which is central to X-ray computed tomography (CT scan) applications. On the Hounsfield scale, distilled water has a value of 0 Hounsfield units (HU), while air is specified as -1000 HU.

In modern medicine, radiodense substances are those that will not allow X-rays or similar radiation to pass. Radiographic imaging has been revolutionized by radiodense contrast media, which can be passed through the bloodstream, the gastrointestinal tract, or into the cerebral spinal fluid and utilized to highlight CT scan or X-ray images. Radiopacity is one of the key considerations in the design of various devices such as guidewires or stents that are used during radiological intervention. The radiopacity of a given endovascular device is important since it allows the device to be tracked during the interventional procedure. The two main factors contributing to a material's radiopacity are density and atomic number. Two common radiodense elements used in medical imagery are barium and iodine.

Medical devices often contain a radiopacifier to enhance visualization during implantation for temporary implantation devices, such as catheters or guidewires, or for monitoring the position of permanently implanted medical devices, such as stents, hip and knee implants, and screws. Metal implants usually have sufficient radiocontrast that additional radiopacifier is not necessary. Polymer-based devices, however, usually incorporate materials with high electron density contrast compared to the surrounding tissue. Examples of radiocontrast materials include titanium, tungsten, barium sulfate, [2] bismuth oxide [3] and zirconium oxide. Some solutions involve direct binding of heavy elements, for instance iodine, to polymeric chains in order to obtain a more homogeneous material which has lower interface criticalities. [4] When testing a new medical device for regulatory submission, device manufacturers will usually evaluate the radiocontrast according to ASTM F640 "Standard Test Methods for Determining Radiopacity for Medical Use."

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<span class="mw-page-title-main">CT scan</span> Medical imaging procedure using X-rays to produce cross-sectional images

A computed tomography scan is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or radiology technologists.

<span class="mw-page-title-main">Radiography</span> Imaging technique using ionizing and non-ionizing radiation

Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical radiography and industrial radiography. Similar techniques are used in airport security. To create an image in conventional radiography, a beam of X-rays is produced by an X-ray generator and is projected toward the object. A certain amount of the X-rays or other radiation is absorbed by the object, dependent on the object's density and structural composition. The X-rays that pass through the object are captured behind the object by a detector. The generation of flat two dimensional images by this technique is called projectional radiography. In computed tomography an X-ray source and its associated detectors rotate around the subject which itself moves through the conical X-ray beam produced. Any given point within the subject is crossed from many directions by many different beams at different times. Information regarding attenuation of these beams is collated and subjected to computation to generate two dimensional images in three planes which can be further processed to produce a three dimensional image.

<span class="mw-page-title-main">Radiology</span> Branch of Medicine

Radiology is the medical discipline that uses medical imaging to diagnose diseases and guide their treatment, within the bodies of humans and other animals. It began with radiography, but today it includes all imaging modalities, including those that use no electromagnetic radiation, as well as others that do, such as computed tomography (CT), fluoroscopy, and nuclear medicine including positron emission tomography (PET). Interventional radiology is the performance of usually minimally invasive medical procedures with the guidance of imaging technologies such as those mentioned above.

<span class="mw-page-title-main">X-ray generator</span> Machine that generates Xrays

An X-ray generator is a device that produces X-rays. Together with an X-ray detector, it is commonly used in a variety of applications including medicine, X-ray fluorescence, electronic assembly inspection, and measurement of material thickness in manufacturing operations. In medical applications, X-ray generators are used by radiographers to acquire x-ray images of the internal structures of living organisms, and also in sterilization.

<span class="mw-page-title-main">Lower gastrointestinal series</span> Radiographs used to examine abnormalities of the colon

A lower gastrointestinal series is a medical procedure used to examine and diagnose problems with the human colon of the large intestine. Radiographs are taken while barium sulfate, a radiocontrast agent, fills the colon via an enema through the rectum.

<span class="mw-page-title-main">Fluoroscopy</span> Production of an image when X-rays strike a fluorescent screen

Fluoroscopy is an imaging technique that uses X-rays to obtain real-time moving images of the interior of an object. There are two main sub-category of Fluoroscopy. Larger, typically Floor, Wall or Ceiling mounted device often called Cath Lab, and Smaller Mobile C-Arm. In its primary application of medical imaging, a fluoroscope allows a surgeon to see the internal structure and function of a patient mainly during surgery so that the pumping action of the heart or the motion of swallowing, for example, can be watched. This is useful for both diagnosis and therapy and occurs in general radiology, interventional radiology, and image-guided surgery.

<span class="mw-page-title-main">Coronary catheterization</span> Radiography of heart and blood vessels

A coronary catheterization is a minimally invasive procedure to access the coronary circulation and blood filled chambers of the heart using a catheter. It is performed for both diagnostic and interventional (treatment) purposes.

<span class="mw-page-title-main">Upper gastrointestinal series</span> Radiographs used to examine abnormalities of the digestive system excluding the colon

An upper gastrointestinal series, also called a barium swallow, barium study, or barium meal, is a series of radiographs used to examine the gastrointestinal tract for abnormalities. A contrast medium, usually a radiocontrast agent such as barium sulfate mixed with water, is ingested or instilled into the gastrointestinal tract, and X-rays are used to create radiographs of the regions of interest. The barium enhances the visibility of the relevant parts of the gastrointestinal tract by coating the inside wall of the tract and appearing white on the film. This in combination with other plain radiographs allows for the imaging of parts of the upper gastrointestinal tract such as the pharynx, larynx, esophagus, stomach, and small intestine such that the inside wall lining, size, shape, contour, and patency are visible to the examiner. With fluoroscopy, it is also possible to visualize the functional movement of examined organs such as swallowing, peristalsis, or sphincter closure. Depending on the organs to be examined, barium radiographs can be classified into "barium swallow", "barium meal", "barium follow-through", and "enteroclysis". To further enhance the quality of images, air or gas is sometimes introduced into the gastrointestinal tract in addition to barium, and this procedure is called double-contrast imaging. In this case the gas is referred to as the negative contrast medium. Traditionally the images produced with barium contrast are made with plain-film radiography, but computed tomography is also used in combination with barium contrast, in which case the procedure is called "CT enterography".

<span class="mw-page-title-main">Barium sulfate</span> Inorganic chemical compound

Barium sulfate (or sulphate) is the inorganic compound with the chemical formula BaSO4. It is a white crystalline solid that is odorless and insoluble in water. It occurs as the mineral barite, which is the main commercial source of barium and materials prepared from it. The white opaque appearance and its high density are exploited in its main applications.

Radiocontrast agents are substances used to enhance the visibility of internal structures in X-ray-based imaging techniques such as computed tomography, projectional radiography, and fluoroscopy. Radiocontrast agents are typically iodine, or more rarely barium sulfate. The contrast agents absorb external X-rays, resulting in decreased exposure on the X-ray detector. This is different from radiopharmaceuticals used in nuclear medicine which emit radiation.

<span class="mw-page-title-main">Scintigraphy</span> Diagnostic imaging test in nuclear medicine

Scintigraphy, also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by external detectors to form two-dimensional images in a similar process to the capture of x-ray images. In contrast, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate techniques from scintigraphy, although they also use gamma cameras to detect internal radiation. Scintigraphy is unlike a diagnostic X-ray where external radiation is passed through the body to form an image.

<span class="mw-page-title-main">Thermogravimetric analysis</span> Thermal method of analysis

Thermogravimetric analysis or thermal gravimetric analysis (TGA) is a method of thermal analysis in which the mass of a sample is measured over time as the temperature changes. This measurement provides information about physical phenomena, such as phase transitions, absorption, adsorption and desorption; as well as chemical phenomena including chemisorptions, thermal decomposition, and solid-gas reactions.

<span class="mw-page-title-main">Chest radiograph</span> Projection X-ray of the chest

A chest radiograph, called a chest X-ray (CXR), or chest film, is a projection radiograph of the chest used to diagnose conditions affecting the chest, its contents, and nearby structures. Chest radiographs are the most common film taken in medicine.

A contrast agent is a substance used to increase the contrast of structures or fluids within the body in medical imaging. Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radiopharmaceuticals, which emit radiation themselves. In x-ray imaging, contrast agents enhance the radiodensity in a target tissue or structure. In magnetic resonance imaging, contrast agents shorten the relaxation times of nuclei within body tissues in order to alter the contrast in the image.

<span class="mw-page-title-main">Opacity (optics)</span> Property of an object or substance that is impervious to light

Opacity is the measure of impenetrability to electromagnetic or other kinds of radiation, especially visible light. In radiative transfer, it describes the absorption and scattering of radiation in a medium, such as a plasma, dielectric, shielding material, glass, etc. An opaque object is neither transparent nor translucent. When light strikes an interface between two substances, in general some may be reflected, some absorbed, some scattered, and the rest transmitted. Reflection can be diffuse, for example light reflecting off a white wall, or specular, for example light reflecting off a mirror. An opaque substance transmits no light, and therefore reflects, scatters, or absorbs all of it. Both mirrors and carbon black are opaque. Opacity depends on the frequency of the light being considered. For instance, some kinds of glass, while transparent in the visual range, are largely opaque to ultraviolet light. More extreme frequency-dependence is visible in the absorption lines of cold gases. Opacity can be quantified in many ways; for example, see the article mathematical descriptions of opacity.

<span class="mw-page-title-main">Projectional radiography</span> Formation of 2D images using X-rays

Projectional radiography, also known as conventional radiography, is a form of radiography and medical imaging that produces two-dimensional images by x-ray radiation. The image acquisition is generally performed by radiographers, and the images are often examined by radiologists. Both the procedure and any resultant images are often simply called "X-ray". Plain radiography or roentgenography generally refers to projectional radiography. Plain radiography can also refer to radiography without a radiocontrast agent or radiography that generates single static images, as contrasted to fluoroscopy, which are technically also projectional.

<span class="mw-page-title-main">Abdominal x-ray</span>

An abdominal x-ray is an x-ray of the abdomen. It is sometimes abbreviated to AXR, or KUB.

<span class="mw-page-title-main">Cone beam computed tomography</span>

Cone beam computed tomography is a medical imaging technique consisting of X-ray computed tomography where the X-rays are divergent, forming a cone.

<span class="mw-page-title-main">X-ray detector</span> Instrument that can measure properties of X-rays

X-ray detectors are devices used to measure the flux, spatial distribution, spectrum, and/or other properties of X-rays.

References

  1. Novelline, Robert. Squire's Fundamentals of Radiology. Harvard University Press. 5th edition. 1997. ISBN   0-674-83339-2.
  2. Lopresti, Mattia; Alberto, Gabriele; Cantamessa, Simone; Cantino, Giorgio; Conterosito, Eleonora; Palin, Luca; Milanesio, Marco (28 January 2020). "Light Weight, Easy Formable and Non-Toxic Polymer-Based Composites for Hard X-ray Shielding: A Theoretical and Experimental Study". International Journal of Molecular Sciences. 21 (3): 833. doi: 10.3390/ijms21030833 . PMC   7037949 . PMID   32012889.
  3. Lopresti, Mattia; Palin, Luca; Alberto, Gabriele; Cantamessa, Simone; Milanesio, Marco (20 November 2020). "Epoxy resins composites for X-ray shielding materials additivated by coated barium sulfate with improved dispersibility". Materials Today Communications. 26: 101888. doi:10.1016/j.mtcomm.2020.101888. S2CID   229492978.
  4. Nisha, V. S; Rani Joseph (15 July 2007). "Preparation and properties of iodine-doped radiopaque natural rubber". Journal of Applied Polymer Science. 105 (2): 429–434. doi:10.1002/app.26040.