| Mixed doubles | |
|---|---|
| 1980 US Open | |
| Champions |  Wendy Turnbull  Marty Riessen |
| Runners-up |  Betty Stöve  Frew McMillan |
| Final score | 7–5, 6–2 |
Greer Stevens and Bob Hewitt were the defending champions but lost in the quarterfinals to Candy Reynolds and Steve Denton.
Wendy Turnbull and Marty Riessen won in the final 7–5, 6–2 against Betty Stöve and Frew McMillan.
Champion seeds are indicated in bold text while text in italics indicates the round in which those seeds were eliminated.
Wendy Turnbull / Marty Riessen (champions) Betty Stöve / Frew McMillan (final) Anne Smith / Kevin Curren (semifinals) Greer Stevens / Bob Hewitt (quarterfinals) Rosemary Casals / 
Anand Amritraj (first round) Candy Reynolds / Steve Denton (semifinals) Ann Kiyomura / Tom Leonard (quarterfinals) Betsy Nagelsen / 
Francisco González (first round)| Final | ||||||
| 1 | Wendy Turnbull Marty Riessen | 7 | 6 | |||
| 2 | Betty Stöve Frew McMillan | 5 | 2 | |||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | W Turnbull M Riessen | 6 | 4 | 6 | |||||||||||||||||||||||
 R Maršíková R Tyler | 2 | 6 | 1 | 1 | W Turnbull M Riessen | 6 | 6 | ||||||||||||||||||||
 R Tomanová V Van Patten | 6 | 3 | 6 | R Tomanová V Van Patten | 1 | 3 | |||||||||||||||||||||
 H Strachoňová  P Feigl | 3 | 6 | 2 | 1 | W Turnbull M Riessen | 6 | 3 | 7 | |||||||||||||||||||
| T Harford J James | 7 | 3 | 2 | 7 | A Kiyomura T Leonard | 3 | 6 | 6 | |||||||||||||||||||
| R Fairbank B Nichols | 6 | 6 | 6 | R Fairbank B Nichols | 7 | 5 | 5 | ||||||||||||||||||||
| R Blount T Graham | 3 | 2 | 7 | A Kiyomura T Leonard | 5 | 7 | 7 | ||||||||||||||||||||
| 7 | A Kiyomura T Leonard | 6 | 6 | 1 | W Turnbull M Riessen | 2 | 7 | 6 | |||||||||||||||||||
| 4 | G Stevens B Hewitt | 6 | 6 | 6 | C Reynolds S Denton | 6 | 5 | 3 | |||||||||||||||||||
J Harrington  L Palin | 1 | 3 | 4 | G Stevens B Hewitt | 6 | 6 | |||||||||||||||||||||
| B Jordan T Delatte | 2 | 6 | 6 | B Jordan T Delatte | 0 | 3 | |||||||||||||||||||||
| S Margolin M Margolin | 6 | 3 | 1 | 4 | G Stevens B Hewitt | 5 | 6 | 2 | |||||||||||||||||||
| P Johnson R Van't Hof | 6 | 6 | 6 | C Reynolds S Denton | 7 | 4 | 6 | ||||||||||||||||||||
| K Jones G Malin | 4 | 3 | P Johnson R Van't Hof | 6 | 3 | 4 | |||||||||||||||||||||
| G Glasgow J Van Linge | 3 | 3 | 6 | C Reynolds S Denton | 3 | 6 | 6 | ||||||||||||||||||||
| 6 | C Reynolds S Denton | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | R Casals A Amritraj | 2 | 4 | ||||||||||||||||||||||||
| B Bunge F McNair | 6 | 6 | B Bunge F McNair | 3 | 6 | 4 | |||||||||||||||||||||
| R Fox V Winitsky | 6 | 6 | R Fox V Winitsky | 6 | 2 | 6 | |||||||||||||||||||||
| A Moulton B Walts | 0 | 3 | R Fox V Winitsky | 2 | 7 | 5 | |||||||||||||||||||||
| S Acker C Leeds | 7 | 7 | 3 | A Smith K Curren | 6 | 6 | 7 | ||||||||||||||||||||
A Buchanan  H Ismail | 5 | 5 | S Acker C Leeds | 4 | 6 | 4 | |||||||||||||||||||||
| J Russell B Scanlon | 2 | 4 | 3 | A Smith K Curren | 6 | 2 | 6 | ||||||||||||||||||||
| 3 | A Smith K Curren | 6 | 6 | 3 | A Smith K Curren | 4 | 5 | ||||||||||||||||||||
| 8 | B Nagelsen F González | 4 | 4 | 2 | B Stöve F McMillan | 6 | 7 | ||||||||||||||||||||
 L Romanov S Krulevitz | 6 | 6 | L Romanov S Krulevitz | 1 | 4 | ||||||||||||||||||||||
| P Smith M Purcell | 6 | 6 | P Smith M Purcell | 6 | 6 | ||||||||||||||||||||||
| P Whytcross J Austin | 2 | 4 | P Smith M Purcell | 5 | 6 | 4 | |||||||||||||||||||||
 C Casabianca R Fagel | 3 | 1 | 2 | B Stöve F McMillan | 7 | 3 | 6 | ||||||||||||||||||||
 A Hobbs E Fromm | 6 | 6 | A Hobbs E Fromm | 6 | 6 | 4 | |||||||||||||||||||||
| R Richards I Năstase | 6 | 6 | 1 | 2 | B Stöve F McMillan | 4 | 7 | 6 | |||||||||||||||||||
| 2 | B Stöve F McMillan | 7 | 3 | 6 | |||||||||||||||||||||||
Colin Dibley and Sandy Mayer were the defending champions but only Dibley competed that year with Haroon Rahim.
John and Tracy Austin defeated Mark Edmondson and Dianne Fromholtz in the final, 4–6, 7–6(8–6), 6–3 to win the mixed doubles tennis title at the 1980 Wimbledon Championships.
Frew McMillan and Betty Stöve defeated the defending champions John and Tracy Austin in the final, 4–6, 7–6(7–2), 6–3 to win the mixed doubles tennis title at the 1981 Wimbledon Championships.
Frew McMillan and Betty Stöve were the defending champions, but lost in the third round to Chris Johnstone and Pam Whytcross.
Wendy Turnbull and Marty Riessen were the defending champions but lost in the first round to Wendy White and Mike Bauer.
Betty Stöve and Wendy Turnbull were the defending champions but they competed with different partners that year, Stöve with Pam Shriver and Turnbull with Rosemary Casals.
Billie Jean King and Martina Navratilova were the defending champions but only Navratilova competed that year with Pam Shriver.
Rosemary Casals and Wendy Turnbull were the defending champions but lost in the quarterfinals to Mima Jaušovec and Kathy Jordan.
The men's doubles tournament at the 1980 US Open was held from August 26 to September 7, 1980, on the outdoor hard courts at the USTA National Tennis Center in New York City, United States. Bob Lutz and Stan Smith won the title, defeating John McEnroe and Peter Fleming in the final.
Bob Hewitt and Frew McMillan were the defending champions, but lost in the semifinals to Ken Rosewall and Fred Stolle.
Bob Hewitt and Greer Stevens defeated the defending champions Betty Stöve and Frew McMillan in the final, 7–5, 7–6(9–7) to win the mixed doubles tennis title at the 1979 Wimbledon Championships.
Tony Roche and Françoise Dürr were the defending champions, but Roche did not compete. Dürr partnered with Marty Riessen but lost in the third round to Bob Hewitt and Greer Stevens.
Bob Hewitt and Greer Stevens were the defending champions but did not compete.
Arthur Ashe and Marty Riessen were the defending champions but none could compete this year, as both players were banned for the Grand Prix tournaments during the dispute between the ILTF and the WCT.
Betty Stöve and Frew McMillan were the defending champions, but lost in the final against Greer Stevens and Bob Hewitt. The score was 6–3, 7–5.
Bob Hewitt and Frew McMillan were the defending champions but lost in the quarterfinals to Marty Riessen and Sherwood Stewart.
Frew McMillan and Betty Stöve were the defending champions and successfully defended their title, defeating Billie Jean King and Ray Ruffels in the final, 6–3, 7-6.
Tom Okker and Marty Riessen were the defending champions but lost in the quarterfinals to Syd Ball and Kim Warwick.
Phil Dent and Billie Jean King were the defending champions but only Billie Jean King competed that year with Vitas Gerulaitis. Vitas Gerulaitis and Billie Jean King lost in the final 6–2, 3–6, 6–3 against Frew McMillan and Betty Stöve.
Owen Davidson and Billie Jean King were the defending champions but lost in the semifinals to Ilie Năstase and Rosemary Casals.