2-acylglycerophosphocholine O-acyltransferase

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2-acylglycerophosphocholine O-acyltransferase
Identifiers
EC no. 2.3.1.62
CAS no. 64295-73-4
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BRENDA BRENDA entry
ExPASy NiceZyme view
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MetaCyc metabolic pathway
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In enzymology, a 2-acylglycerophosphocholine O-acyltransferase (EC 2.3.1.62) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine CoA + phosphatidylcholine

Thus, the two substrates of this enzyme are acyl-CoA and 2-acyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and phosphatidylcholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase. Other names in common use include 2-acylglycerol-3-phosphorylcholine acyltransferase, and 2-acylglycerophosphocholine acyltransferase. This enzyme participates in glycerophospholipid metabolism.

Related Research Articles

<span class="mw-page-title-main">Glycerophospholipid</span> Class of lipids

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<span class="mw-page-title-main">Diacylglycerol cholinephosphotransferase</span>

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<span class="mw-page-title-main">1-Lysophosphatidylcholine</span>

2-acyl-sn-glycero-3-phosphocholines are a class of phospholipids that are intermediates in the metabolism of lipids. Because they result from the hydrolysis of an acyl group from the sn-1 position of phosphatidylcholine, they are also called 1-lysophosphatidylcholine. The synthesis of phosphatidylcholines with specific fatty acids occurs through the synthesis of 1-lysoPC. The formation of various other lipids generates 1-lysoPC as a by-product.

References