2009 swine flu pandemic in the United Kingdom

Last updated

2009 swine flu pandemic in the UK
Disease Swine flu
Virus strain H1N1
First outbreakNorth America, possibly Central Mexico [1]
Arrival date27 April 2009 (First cases in Scotland) [2]
Confirmed casesPossible 100,000+ cases (As of January 2010)
Deaths
392 (28 January 2010)
Government website
Health Protection Agency (HPA) [2]
*Data from Health Protection Agency [2]

The 2009 swine flu pandemic was a global outbreak of a new strain of influenza A virus subtype H1N1, first identified in April 2009, termed Pandemic H1N1/09 virus by the World Health Organization (WHO) [3] and colloquially called swine flu. The outbreak was first observed in Mexico, [1] [4] and quickly spread globally. On 11 June 2009, the WHO declared the outbreak to be a pandemic. [5] [6] The overwhelming majority of patients experienced mild symptoms, [5] but some persons were in higher risk groups, such as those with asthma, diabetes, [7] [8] obesity, heart disease, who were pregnant or had a weakened immune system. [9] In the rare severe cases, around 3–5 days after symptoms manifest, the sufferer's condition declines quickly, often to the point of respiratory failure. [10]

Contents

The virus reached the United Kingdom in April 2009. [11] The first cases were confirmed on 27 April 2009 in passengers returning from Mexico. The first case of person to person transmission within the UK was announced on 1 May 2009. [12] In the UK, 5- to 14-year-olds were the age group predominantly affected. [13] Laboratory tests demonstrated that older people had some immunity. [14]

After a slow start, the virus spread rapidly in the UK in July 2009, with new cases peaking at 110,000 in the last week of that month, according to The Health Protection Agency's modelling estimate, but declining sharply in the first week of August 2009. [2] [15] Cases fell progressively down to 3,000 in the first week of September 2009, then began to rise again. [2] The decline in cases during the summer had been predicted, but a large surge was expected in the autumn to coincide with the normal flu season. [15] Cases rose to 84,000 by the end of October, well below the summer's peak, and then declined during November. [2]

UK 2009 Swine Flu cases per week. Health Protection Agency modelling Swineflu uk hpa model.svg
UK 2009 Swine Flu cases per week.
Health Protection Agency modelling

Outbreak timeline

2009UK swine flu outbreak, milestone
27 AprilFirst two UK H1N1 cases confirmed in Scotland after a flight from Mexico. [17]
29 April Paignton Community and Sports College closes for about a week in first school closure. [18]
1 MayFirst two UK person to person transmissions confirmed. [19]
2 MayFurther schools are temporarily closed from this date. [20] [21] [22] [23]
7 MayHPA issues advice on exclusion from schools and workplaces. [24]
8 MayHPA issues "advice on actions to be taken in a school in the event of a probable or confirmed case of "swine flu" being identified in a school pupil", [25] in which closure for 7 days is advised when appropriate.
The virus from European samples isolated and its full genetic fingerprint determined by UK researchers, [26] following similar work in the US on the virus in the American continent.
17 MayOne hundredth confirmed case. [27]
22 MayHPA staff no longer routinely meet flights from Mexico. Contact tracing of passengers deemed to be at risk of swine flu carried out on the basis of risk, as for other communicable diseases. [28]
26 MayThe largest single outbreak so far, with 50 [29] confirmed cases identified at a Birmingham primary school (later increased to 74 [30] ).
13 JuneOver 1,000 cases of swine flu confirmed in the UK. [2]
14 JuneFirst death, of patient with underlying health problems, reported at the Royal Alexandra Hospital in Paisley, Glasgow, Scotland. [31]
26 JuneSecond death, of patient with underlying health problems, of a six-year-old girl at Birmingham Children's Hospital in the West Midlands region. Her death was reported on 29 June. [32]
30 June6,000 cases of swine flu confirmed in the UK. [33]
2 JulyThe HPA announced that the containment approach to reduce spread was no longer appropriate given the clusters of cases around the UK, and would be replaced by a treatment phase in which everybody presenting symptoms would be treated if necessary without laboratory confirmation, but contacts would not be traced. Daily reports of confirmed cases are no longer being published. [34]
6 JulyThree deaths in the UK bringing the total to seven. The new victims include two 9-year-old girls. NHS stated all three had "serious underlying health problems". The victims are from South London and Dewsbury in West Yorkshire. [35]
9 JulyThe government announced that there are now over 9,000 cases of Swine flu in the UK and 14 patients have died, [36] 2 in Scotland, 5 in London, and the remainder elsewhere in England. [37]
10 JulyA 15th person has died from swine flu in Essex. Unlike previous cases, they had no underlying health conditions. [38]
13 July2 more people die with swine flu in England. [39] One, a 6-year-old girl, who died of septacemia, and a middle-aged doctor. Initial reports that he died of Pulmonary Embolism were disproved on his final Post Mortem, which concluded that Swine Flu was a contributing factor in his death. [40]
16 JulyIt emerges that 12 more people have died. The total now stands at 29. 85,000 people are estimated to be affected by swine flu as of 16 July, with 55,000 new infections in the preceding week according to HPA modelling. [41]
23 JulyThe National Pandemic Flu Service goes live in England for the first time. [42] Shortly after it goes live, the Service gets over 2,000 hits per second. Scotland, Wales and Northern Ireland can opt in for the service if the rate of infection increases.
21 AugustThe first swine flu related death in Wales has been confirmed after a 55-year-old woman died. [43]
15 OctoberIts announced that there were 27,000 new swine flu cases in the past week, up from 18,000 the week before, and new cases were rising more slowly than expected, but the number requiring treatment in intensive care had increased from 47 out of 290 hospitalised last week to 74 out of 364 hospitalised this week. The number of deaths in the UK rose to 106. [44]
21 October Swine Flu Vaccine became available across the UK and mass immunisation programme gets under way. [45]
22 OctoberIt's announced that Swine flu cases in the UK almost doubled from the previous week to 53,000. The number of patients needing hospital care has risen to 506 in England with 99 in critical care – the highest since the pandemic began. Deaths increased to 128. The total number of cases is now estimated to be 435,000. [46]
29 OctoberSwine Flu cases rose by almost 50% to 78,000 new cases. Deaths increased to 137. Hospitalised patients increased to 751, of which 157 are in intensive care including nine people on ECMO (extracorporeal membrane oxygenation) machines. It is now estimated that there have been 521,000 cases in England since the pandemic began. It is also reported that one in three deaths are not in the "priority vaccination group" as currently defined by the government. [47]
5 NovemberNew Swine Flu cases increased to 84,000. Deaths increased to 154. 848 people are hospitalised, 172 of which are in intensive care. It is thought that the rise in new cases was smaller this week due to school children being on their "half term" holidays. Andrew Lansley, the Shadow Health Secretary, called on the Government to commit to vaccinating all schoolchildren in the country, as well as university students. [48]
12 NovemberThe number of new swine flu cases in the past week fell by nearly a quarter to 64,000 in England. Deaths increased to 182 (124 deaths in England, 33 in Scotland, 11 in Northern Ireland and 14 in Wales). [49] Hospitalised patients fell to 785, of whom 173 are in intensive care. The Chief Medical Officer, Sir Liam Donaldson, said that the drop in new cases could be due to school children's half term break, the impact of which could last two weeks and that next week's figures should give a clearer picture of how the virus is developing. Shadow health secretary Andrew Lansley said the latest figures again illustrated the importance of vaccinating children. "This is further evidence that we need to begin planning a school and college-based vaccination programme immediately." [50] [51]
19 NovemberNew Swine Flu cases decreased again from the previous week, down to 53,000 new cases in England in the last week. 783 patients were hospitalised. The number of deaths related to swine flu in the UK increased to 214 [52] (142 in England). The HPA estimates that there have now been a total of 715,000 cases of swine flu since the pandemic began. [53] [54] The government has announced that all children under the age of five are to get the swine flu vaccine. Chief Medical Officer Sir Liam Donaldson said there had been a rise in serious illnesses recently among young children that was "causing concern". "We consider them to be seriously at risk". Latest figures showed that 81% of under-5s hospitalised with swine flu had no underlying health issues. The Conservative Party says that all under-25s should get the vaccine next. [49] [55]
20 NovemberThe first officially confirmed cases of person-to-person transmission of a Tamiflu-resistant strain of swine flu in the world are reported to have happened between 5 patients at the University Hospital of Wales in Cardiff. [56]
26 NovemberThe number of new swine flu cases continue to fall, with 46,000 new cases in the last week, 7,000 less than the week before. However Swine flu deaths in England in a single week reached their highest level with a record 21 deaths, bringing the total deaths to 245 in the UK (163 in England). There were 753 hospitalised patients, 154 of those being in intensive care. The Government estimates more than a million people have now been vaccinated, roughly a month after the vaccination program started (that figure excludes health care workers, who are also being offered the vaccine). That means only about 1 in 10 of the 11 million people in the "at risk" priority groups have so far been vaccinated. Professor David Salisbury, head of immunisation at the Department of Health was disappointed, saying "Clearly I would have liked a bigger number...I would like to see an acceleration now". [57] [58]
3 DecemberNew Swine Flu cases more than halved from the previous week, dropping to 22,000 new cases in England in the last week. Total deaths increased to 270 (178 deaths in England). There are 747 hospitalised patients – 161 of which are in critical care. A further 600,000 people were vaccinated in the last week, bringing total to 1.6 million people. In addition to that, 275,000 healthcare workers have been vaccinated out of nearly 2 million. Chief Medical Officer Sir Liam Donaldson said it was still "too early" to know whether the downward trend in new cases would continue and that his biggest worry was the virus mutating or mixing with other viruses and creating a new, more dangerous virus. Prof David Salisbury, head of immunisation at the Department of Health, said the vaccines with adjuvants, substances which boost the immune system and allow less active ingredient to be used in each dose, offer good protection even if the virus does change; "One of the advantages with adjuvanted vaccines is their ability to protect against drifted (mutated) strains. It opens the door for a whole new strategy in dealing with flu." The GlaxoSmithKline vaccine, Pandemrix, which forms the bulk of the governments mass vaccination programme with 11.2 million doses delivered so far to health services, contains an adjuvant. [59] [60] [61] [62]
10 DecemberNew Swine Flu cases halved from the previous week, to 11,000 new cases in England. Deaths increased to 283 (191 in England) and there were currently 636 hospitalised patients. The number of people vaccinated increased to 2.3 million. The estimated total number of cases is 795,000. The Chief Medical Officer Sir Liam Donaldson revealed that the swine flu pandemic is "considerably less lethal" than feared. An analysis of deaths to 8 November showed that 26 people have died for every 100,000 cases in England, meaning a death rate of 0.026% in those infected with Swine Flu. The highest death rate was in those aged over 65, and lowest in those aged 5 to 14. The average age at death was 39. Of the patients who died, 67% were in the "high risk" vaccination priority group and were eligible to get vaccinated, 36% had either no or only mild pre-existing illnesses. Sir Liam again urged people to come forward for immunisation, commenting that a lower impact than previously feared "is not a justification for public health inaction. Our data supports the priority vaccination of high risk groups. Given that a substantial minority of deaths occur in previously healthy people, there is a case for extending the vaccination programme". [63] [64] [65] [66]
17 DecemberNew Swine Flu cases again fell with 9000 people infected in last week. Total deaths in the UK increased to 299 (203 in England). The number of currently hospitalised patients fell to 523 patients of which more than 100 were in intensive care. 3 million people out of the 9 million in the 1st vaccination priority groups have now been vaccinated including 100,000 pregnant women. In addition to that, 343,000 front line health workers have also been vaccinated. It appears that the second wave of Swine Flu is coming to an end but experts warn cases could rise again in the future in a "third wave" of swine flu. [67] [68] [69] [70] [71]
24 DecemberNew cases of Swine Flu fell by a third to 6,000 cases this week. The total death figures will be updated by the HPA on Thursday 7 January. The number of hospitalised patients declined to 454 currently in hospital (as of 8 am on 23 December). [72]
31 DecemberThe HPA did not release estimate numbers this week, instead saying that flu activity is continuing to decrease across the UK but some caution must be exercised as this may be influenced by the holiday period. 496 patients were currently hospitalised in England as of 8 am on 30 December (an increase from last week). A more detailed update will be released next week. [73]
8 JanuarySwine Flu cases continued to decrease, down to less than 5,000 new cases in the preceding week. Total UK deaths increased to 360 (251 in England, 64 in Scotland, 28 in Wales and 17 in Northern Ireland). Hospitalised patients in England (as of 8 am on 6 January) numbered 393, of whom 103 were in critical care. Only 3.2 million people had been vaccinated (out of 9 million in the priority groups), including 113,000 pregnant women (out of roughly 600,000), 86,000 under-5s (out of more than 3 million) and an additional 373,000 front-line health workers (out of more than a million). The Head of Immunisation at the Department of Health, Professor David Salisbury urged all those in the at-risk priority groups to get immunised, especially children under five and those with underlying health conditions, because while cases were currently down, it was not clear what would happen with swine flu over the year ahead. [74] [75] [76]

Reported cases

Until 2 July 2009 the HPA published daily reports [2] of laboratory-confirmed cases with breakdown by region, by age, and by source of infection (travel, community, etc.). From that date routine laboratory testing of all suspected cases and reporting of figures was discontinued. As of 8 July 2009 figures shown in this article are laboratory confirmed cases reported on 2 July.[ citation needed ]

Deaths are often reported as occurring "after contracting the swine flu virus" without flu being necessarily the cause of death of people with underlying health problems.[ citation needed ]

Researchers at Imperial College London said in July 2009 that the best estimate was that about 0.5% of those who get swine flu bad enough to seek medical help die from it, a figure very similar to the estimate for seasonal influenza. [77] The World Health Organization (WHO) said the pandemic was over in August 2010. [78] As of 2023, it is seen as "circulating in humans seasonally," [79] posing the same risk of other seasonal flu viruses.

Cases by region

Figures for laboratory confirmed cases in England and Scotland are as of 2 July 2009, after which routine testing was discontinued. Deaths are of people with swine flu, not necessarily caused by swine flu.
RegionCases
Laboratory
confirmed†		Confirmed
Deaths
Totals [2] 28,456 [80] 392
England19,995 [80] 279 [81]
Northern Ireland 1,355 [80] 18 [82]
Scotland6,450 [80] 67 [83]
Wales 656 [80] 28 [84]
† The cumulative total number of cases, including patients who have recovered.

Laboratory-confirmed
cases of AH1N1 Influenza
in the United Kingdom
up to 2 July 2009

Health Protection Agency
update bulletins

2009 swine flu pandemic in the United Kingdom
UK weekly GP consultations for influenza-like illness. QResearch data from Health Protection Agency Swineflu uk rate.svg
UK weekly GP consultations for influenza-like illness.
QResearch data from Health Protection Agency

Detailed reports

On 25 April 2009, a member of British Airways cabin crew was taken to Northwick Park Hospital in Harrow and quarantined after falling ill with flu-like symptoms on a flight from Mexico City though he was later found not to have swine flu. [86]

On 26 April, two people were admitted to Monklands Hospital in Airdrie, North Lanarkshire, with mild flu-like symptoms after returning from Mexico. [87] [88] The next day, the Cabinet Secretary for Health and Wellbeing, Nicola Sturgeon, confirmed that these were cases of the swine influenza A (H1N1) virus. [17] Authorities in both Scotland and England stated that there were no plans to trace the fellow airline passengers who may have travelled alongside the couple, since the authorities do not classify them as "close contacts". [89] These cases along with one in Spain are the first confirmed cases in Europe. [90]

At noon on 29 April the government reported three more confirmed cases in the UK, including the first cases in England. All three had recently returned from Mexico. [91] The secondary school, Paignton Community and Sports College, closed for seven days. [18]

By 26 May the number of people who had contracted the disease in-country increased to 125, the highest in Europe and triple the second highest, Spain. [92]

On 28 May, sixty four people connected with a primary school in Birmingham were diagnosed with swine flu . [93]

On 8 June the HPA issued a report stating that the majority of cases are in school age children and young adults, [94] which has not been the case in most pandemics with the notable exception of the 1918 flu pandemic. [95]

On 25 June the chief medical officer Sir Liam Donaldson said certain areas were seeing rapid community spread which meant that it was no longer practical to attempt in those areas (initially parts of London, the west Midlands and east Berkshire [96] ) to put a ring around the outbreaks by tracing the people with whom confirmed cases have come into contact and giving them drugs to try to prevent flu developing. In these areas, anti-viral drugs may in the future only be given to people showing symptoms, and tracing of contacts will stop. The contingency plans always envisaged the containment phase would not last indefinitely. [97] The start of the treatment (as against containment) approach was announced on 2 July 2009. [34]

Every year in late June and early July the Wimbledon tennis championships are held in London, attracting worldwide interest and with many hours of UK television coverage every day. On 1 July 2009 it was reported that 28 Wimbledon staff had been asked to stay at home with flu-like symptoms. Two named players are reported to have caught the virus.

A study published in the August 2009 issue of The Lancet (available on 20 July) suggests that prolonging the school holidays could reduce the spread of the virus by up to 17%. This would be disruptive, and would not reduce the overall number of infections, but could delay the spread and buy time for preparation of a vaccine. The government's advice is that schools should not be closed, but that the evidence will be reviewed in August as school summer holidays end. [98] [99]

Public information

The Department of Health announced on 29 April 2009 that they intended to send an information leaflet on swine flu to every household in the UK. The information leaflets were distributed at the beginning of May. [100] [101] On 29 April, Alan Johnson announced that television and radio advice would also be broadcast starting on 30 April. [102] The slogan "Catch it, Bin it, Kill it" was used to encourage good hand and respiratory hygiene. [103] On 30 April 2009, a swine flu information line was launched with advice on setting up "flu friends" (this is not the National Flu Line service mentioned below). [102]

The Department of Health Pandemic Plan (revised November 2007) states "UK health departments (directorate in Scotland) will run a national door drop and advertising campaign in Phase 5, alerting the public to the heightened risk, emphasising the need for personal preparation and socially responsible behaviour. A public information film will demonstrate how to slow the spread of the virus, and the National Flu Line service will be available. Information materials will also be available through primary care, pharmacies and on the Department of Health website." [104] After criticism of the lateness of its launch, it was announced in late July that the National Flu Line service was to be launched on 24 July 2009. [105] [106]

There are government websites with general information and the latest updates on human swine flu in England, [2] Northern Ireland, [107] Scotland, [108] [109] and Wales. [110]

The HPA website includes frequently updated advice for the public, [111] advice on exclusion from schools and workplaces [24] (and a document specifically for schools), [25] and information for health professionals. [112]

During the initial containment phase of the swine flu outbreak the HPA published detailed information in daily and weekly reports linked from its Epidemiological data page on its website. [2] On 2 July, when the policy of containment was dropped in favour of treatment of presumed cases, the daily updates of laboratory confirmed cases were stopped. [113] A weekly epidemiological update and pandemic flu update are published each Tuesday, with much detailed information including regional information and breakdown by age.[ citation needed ]

Control measures

On 11 May 2009 UK epidemiologists at Imperial College London considered that H1N1 swine flu was spreading fast enough to justify the preparations for a pandemic. It was showing "sustained human-to-human transmission", thereby justifying the WHO's pandemic phase 5 rating. It is estimated that on average each person who contracts flu passes it on to between 1.4 and 1.6 other people, no worse than the three influenza pandemics of the twentieth century. Early analysis suggested that the spread was likely to be similar to the earlier pandemics. Up to the date of the study, clinical severity was similar to 1957 and less than 1918 flu pandemic. However, the clinical severity of the outbreak and how the virus will evolve was yet to be predicted. [114]

Travel to and from affected areas

On 27 April, the Foreign & Commonwealth Office advised against all but essential travel to Mexico [115] and stated that British citizens in Mexico... "may wish to consider whether they should remain in Mexico at this time". On 28 April the Mexican Tourist Board estimated that there were "a few thousand" British tourists in Mexico. [116]

Holiday companies Thomas Cook and Airtours said that between them they had about "3,000 holidaymakers in Mexico" as of 28 April 2009. [117] The first British tourists being brought back early from Mexico on 28 April 2009 told reporters that they had received little or no information about health precautions, either from the Mexican authorities, hotels, or from local tour guides. [118]

A leaflet was being distributed at all ports of entry into the UK providing passengers arriving in the UK with information on swine flu. [119]

Until 21 May HPA staff met travellers arriving from Mexico. This was discontinued on 22 May, but advice remained that travellers from affected areas who become unwell within seven days of arrival, and contacts with symptoms of a confirmed or probable case, should stay at home and contact their GP or NHS Direct. Contact tracing of passengers deemed to be at risk of swine flu will be carried out on the basis of risk, as for other communicable diseases. [28]

Preparations

Tamiflu, influenza anti-viral drug Tamiflu.JPG
Tamiflu, influenza anti-viral drug

Information, advice, and guidance both general and for specific cases (schools, workplaces) is being made available and updated by the HPA (see Public information campaign section above).

As of 13 June 2009 the government estimated that the UK has enough anti-viral drugs for 50% of the population but has plans to raise that figure to 80%. [120]

There is a pandemic plan covering topics from distributing the drugs and setting up helplines to closing schools and banning public events which was tested in a large exercise in 2007. [104] [121] There is also a specific response plan for London. [122] Oseltamivir (Tamiflu) and zanamivir (Relenza), the two anti-virals known to be effective, must be taken within 48 hours of onset of symptoms or earlier to be effective; [123] the positive effects are greatest if treatment is started within six hours. [124]

The HPA reported in its 24 June 2009 weekly epidemiological report that all 17 samples of the virus laboratory tested for resistance that week were found to be sensitive to oseltamivir and zanamivir, but resistant to amantadine. [125] The first case of resistance of the virus to oseltamivir, in Denmark, was reported on 29 June 2009. [126]

On 5 May 2009 plans were announced for pupils unable to sit examinations at schools affected by flu to be assessed in other ways to ensure that children are not disadvantaged. [127]

The Department of Health has listed all the pandemic flu guidance that it had published as of 8 June 2008. [128]

Testing suspected cases

Genetic analysis

Samples from suspected cases have been analysed by the National Institute for Medical Research in London, which is also examining samples of the U.S. strain of the disease. [129]

By 8 May 2009 the US Centers for Disease Control and Prevention had made genetic information on the swine flu virus available, and the virus from European samples had been isolated and its full genetic fingerprint determined by UK researchers. [26] The genetics and effects of the virus in general are discussed in the article on the 2009 swine flu pandemic.[ citation needed ]

Diagnosis

The fastest way for laboratory confirmation of swine flu is by the PCR method, described as a real-time method. According to the World Health Organization there are four laboratories in the UK able to perform PCR to diagnose influenza A (H1N1) virus infection in humans: Regional Virus Laboratory, Royal Victoria Hospital, Belfast, NI; Regional Virus Laboratory, Gartnavel General Hospital, Glasgow, Scotland; Health Protection Agency, Centre for Infections, Enteric, Respiratory, & Neurological Virus Laboratory, London; WHO Collaborating Centre for Reference and Research on Influenza, National Institute for Medical Research, London. [130]

Another laboratory confirmation is a fourfold increase in virus-specific antibodies 10 to 14 days later. [131]

From 2 July 2009 when a treatment, rather than containment, approach was adopted, the official clinical diagnostic criteria became: "fever (pyrexia ≥38 °C) or a history of fever, and also influenza-like illness (two or more of the following symptoms: cough; sore throat; rhinorrhoea; limb or joint pain; headache; vomiting or diarrhoea) or severe and/or life-threatening illness suggestive of an infectious process". [132]

"Laboratory confirmed" cases

Professor Neil Ferguson, an epidemiologist at Imperial College London, who advises the Government and the World Health Organization, said on 8 June 2009 that HPA statistics were at best accounting for half of cases. [133]

In the USA mathematical modelling based on surveys estimated that there were about 1 million cases of H1N1 flu on 25 June 2009, compared to 28,000 reported officially. [134] [135] Such a study has not been carried out in the UK.[ citation needed ]

As of 2 July 2009 GPs will diagnose based on clinical observation and routine swabbing will stop, [136] and the HPA will "no longer be providing a daily update of the numbers of cases confirmed through laboratory tests" [137]

Hygiene recommendations

According to the Health Protection Agency's "Swine flu: frequently asked questions" web page, [138] transmission of this new virus is thought to occur in the same way as seasonal flu:

When the issue of touching your eyes, nose or mouth is combined with other infection control practices and good hygiene measures as recommended by the Health Protection Agency's website, [2] the following recommendations emerge as important ways to help reduce the spread of swine flu and other viruses:[ citation needed ]

For people belonging to a high-risk group it is particularly important that they start taking anti-virals as soon as possible after infection. High-risk groups include people with long-term conditions, those over 65, children under five and pregnant women. [132]

Immunity

A study at the U.S. Centers for Disease Control and Prevention published in May 2009 found that children had no pre-existing immunity to the new strain but that adults, particularly those over 60, had some degree of immunity. Children showed no cross-reactive antibody reaction to the new strain, adults aged 18 to 64 had 6–9%, and older adults 33%. [14] The large proportion of cases in the UK affecting children and young adults is consistent with this pattern of resistance. [139] [140]

Vaccine

The usual seasonal flu vaccines gave little or no immunity against the new strain of flu. There was an international program to produce a vaccine which would be effective against the new H1N1 strain. The chief medical officer Sir Liam Donaldson said on 25 June that it seemed likely that the UK would receive the first batches of vaccines slightly earlier than expected, possibly from August rather than the autumn as first expected, although some industry sources do not expect supplies to be available so soon. The government had contracts for 132 million doses. [97] There were risks involved in shifting resources to the new vaccine: it would not be possible to produce the seasonal flu vaccine, and it was possible that the virus will mutate to make a vaccine developed before the mutation ineffective.[ citation needed ]

Possible use of face-masks

Alan Johnson, Health Secretary at the time of the outbreak Alan Johnson -9Oct2007-2.jpg
Alan Johnson, Health Secretary at the time of the outbreak

The then Health Secretary Alan Johnson told MPs on 27 April that "Although we are aware that face-masks are being given out to the public in Mexico, the available scientific evidence does not support the general wearing of face-masks by those who are not ill, whilst going about their normal activities." [141]

Professor Steve Field, chairman of the Royal College of General Practitioners, said people in the UK were "perfectly safe at the moment", and did not need to start wearing face-masks or stop eating pork. [142]

The Head of Pandemic Planning at the Royal College of General Practitioners, Dr Maureen Baker, stated on 27 April that "Masks become ineffective when they become damp or after a few hours. There has been a lot of debate on the use of face-masks and some authorities say that, in the community, the most effective use is to give to patients who may have symptoms when they present in the surgery – that should help reduce the infectivity of that patient to surgery staff and other patients. I expect the Department of Health will issue guidance on use of face-masks if we move into a pandemic phase." [143] Masks may not protect the wearer from inhalation of the virus, but might protect other people from picking up the virus from the wearer. [121]

Professor John Oxford, a virologist at leading London hospital, The Barts and the London, said: "Really, there is very little evidence that masks actually offer much protection against flu." [144]

It was reported that the UK government was urgently seeking to acquire more face-masks. [145] [146]

The advice given by authorities in several countries on the use of face masks has been summarised in an article, with many references, published on 4 June 2009. [147]

Aside from their obligations under health and safety legislation, employers can help to minimise the spread of the virus and support good infection control practice by positively encouraging any employee who reports feeling unwell with influenza-like symptoms to stay at home until their symptoms resolve, by sending people home who develop influenza-like illness at work (avoiding public transport and wearing a face mask if possible) and by ensuring that stocks of surgical face-masks are available in the workplace for symptomatic staff to wear until they get home.

—  DoH Pandemic Flu Plan [104] , November 2007

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<span class="mw-page-title-main">2009 swine flu pandemic</span> 2009–2010 pandemic of swine influenza caused by H1N1 influenza virus

The 2009 swine flu pandemic, caused by the H1N1/swine flu/influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, was the third recent flu pandemic involving the H1N1 virus. The first identified human case was in La Gloria, Mexico, a rural town in Veracruz. The virus appeared to be a new strain of H1N1 that resulted from a previous triple reassortment of bird, swine, and human flu viruses which further combined with a Eurasian pig flu virus, leading to the term "swine flu".

The 2009 flu pandemic in the United States was caused by a novel strain of the Influenza A/H1N1 virus, commonly referred to as "swine flu", that was first detected on 15 April 2009. While the 2009 H1N1 virus strain was commonly referred to as "swine flu", there is no evidence that it is endemic to pigs or of transmission from pigs to people; instead, the virus spreads from person to person. On April 25, the World Health Organization declared a public health emergency, followed concurringly by the Obama administration on April 26.

<span class="mw-page-title-main">2009 swine flu pandemic in Canada</span>

The 2009 swine flu pandemic in Canada was part of an epidemic in 2009 of a new strain of influenza A virus subtype H1N1 causing what has been commonly called swine flu. In Canada, roughly 10% of the populace has been infected with the virus, with 428 confirmed deaths ; non-fatal individual cases are for the most part no longer being recorded. About 40% of Canadians have been immunized against H1N1 since a national vaccination campaign began in October 2009, with Canada among the countries in the world leading in the percentage of the population that has been vaccinated. The widespread effect of H1N1 in Canada raised concerns during the months leading to the XXI Olympic Winter Games, which took place in Vancouver in February 2010.

<span class="mw-page-title-main">2009 swine flu pandemic timeline</span>

This article covers the chronology of the 2009 novel influenza A (H1N1) pandemic. Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths, and relevant sessions and announcements of the World Health Organization (WHO), the European Union , and the U.S. Centers for Disease Control (CDC).

In March and April 2009, an outbreak of a new strain of influenza commonly referred to as "swine flu" infected many people in Mexico and other parts of the world, causing illness ranging from mild to severe. Initial reports suggested that the outbreak had started in February due to farming practices at a pig farm half-owned by Smithfield Foods. Smithfield Foods stated that it had found no clinical signs or symptoms of the presence of swine influenza in the company's swine herd, or among its employees at its joint ventures in Mexico, that it routinely administers influenza virus vaccination to their swine herds and that it conducts monthly testing for the presence of swine influenza. The new strain was identified as a combination of several different strains of Influenzavirus A, subtype H1N1, including separate strains of this subtype circulating in humans and in pigs.

<span class="mw-page-title-main">2009 swine flu pandemic by country</span>

This article deals with the status and efforts regarding the 2009 swine flu pandemic by country and continent/region.

<span class="mw-page-title-main">Pandemic H1N1/09 virus</span> Virus responsible for the 2009 swine flu pandemic

The pandemic H1N1/09 virus is a swine origin influenza A virus subtype H1N1 strain that was responsible for the 2009 swine flu pandemic. This strain is often called swine flu by the public media due to the prevailing belief that it originated in pigs. The virus is believed to have originated around September 2008 in central Mexico.

<span class="mw-page-title-main">2009 swine flu pandemic in Asia</span>

The 2009 flu pandemic in Asia, part of an epidemic in 2009 of a new strain of influenza A virus subtype H1N1 causing what has been commonly called swine flu, afflicted at least 394,133 people in Asia with 2,137 confirmed deaths: there were 1,035 deaths confirmed in India, 737 deaths in China, 415 deaths in Turkey, 192 deaths in Thailand, and 170 deaths in South Korea. Among the Asian countries, South Korea had the most confirmed cases, followed by China, Hong Kong, and Thailand.

<span class="mw-page-title-main">2009 swine flu pandemic in North America</span>

The 2009 swine flu pandemic in North America, part of a pandemic in 2009 of a new strain of influenza A virus subtype H1N1 causing what has been commonly called swine flu, began in the United States or Mexico.

<span class="mw-page-title-main">2009 swine flu pandemic in Europe</span>

The 2009 flu pandemic in Europe was part of a pandemic involving a new strain of influenza, subtype H1N1. H1N1 is commonly called swine flu. The pandemic infected at least 125,550 people in Europe. There were 458 confirmed deaths in Turkey, 438 confirmed deaths in Russia, and 457 confirmed deaths in the United Kingdom.

<span class="mw-page-title-main">2009 swine flu pandemic in Africa</span>

The 2009 flu pandemic hit Africa two months later than other continents with the first case reported in Egypt on June 2, 2009. As of December 1, 30 countries in Africa had reported cases and 7 countries in Africa had reported a total of 108 deaths. It was the least affected continent.

<span class="mw-page-title-main">2009 swine flu pandemic vaccine</span> Protection against the H1N1/09 virus

The 2009 swine flu pandemic vaccines were influenza vaccines developed to protect against the pandemic H1N1/09 virus. These vaccines either contained inactivated (killed) influenza virus, or weakened live virus that could not cause influenza. The killed virus was injected, while the live virus was given as a nasal spray. Both these types of vaccine were produced by growing the virus in chicken eggs. Around three billion doses were produced, with delivery in November 2009.

The United States experienced the beginnings of a pandemic of a novel strain of the influenza A/H1N1 virus, commonly referred to as "swine flu", in the spring of 2009. The earliest reported cases in the US began appearing in late March 2009 in California, then spreading to infect people in Texas, New York, and other states by mid-April. Early cases were associated with recent travel to Mexico; many were students who had traveled to Mexico for Spring Break. This spread continued across the country's population and by the end of May there were approximately 0 confirmed cases throughout all 50 states.

<span class="mw-page-title-main">2009 swine flu pandemic in New Zealand</span>

The 2009 swine flu pandemic in New Zealand was caused by a novel strain of the A/H1N1 influenza virus. A total of 3,175 cases and 69 deaths were recorded, although a seroprevalence study estimated that around 800,000 individuals may have been infected during the initial wave of the pandemic.

<span class="mw-page-title-main">2009 swine flu pandemic in Turkey</span>

The 2009 flu pandemic was a global outbreak of a new strain of influenza A virus subtype H1N1, first identified in April 2009, termed Pandemic H1N1/09 virus by the World Health Organization (WHO) and colloquially called swine flu. The outbreak was first observed in Mexico, and quickly spread globally. On 11 June 2009, WHO declared the outbreak to be a pandemic. The overwhelming majority of patients experience mild symptoms", but some persons are in higher risk groups, such as those with asthma, diabetes, obesity, heart disease, or who are pregnant or have a weakened immune system. In the rare severe cases, around 3–5 days after symptoms manifest, the person's condition declines quickly, often to the point respiratory failure.

The 2009 swine flu pandemic was a global outbreak of a new strain of influenza A virus subtype H1N1, first identified in April 2009, termed Pandemic H1N1/09 virus by the World Health Organization (WHO) and colloquially called swine flu. The outbreak was first observed in Mexico, and quickly spread globally. On the 11th of June 2009, the WHO declared the outbreak to be a pandemic. The overwhelming majority of patients experience mild symptoms, but some persons are at higher risk of suffering more serious effects; such as those with asthma, diabetes, obesity, heart disease, or those who are pregnant or have a weakened immune system. In the rare severe cases, around 3–5 days after symptoms manifest, the sufferer's condition declines quickly, often to the point respiratory failure. Although Ukraine was not (very) affected at first there was on outbreak of the virus in Western Ukraine in early November 2009 that led to the closing of public buildings and cancellation of meetings for three weeks.

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