The 2000 season was the St. Louis Rams' 63rd in the National Football League (NFL) and their sixth in St. Louis. For the first time in franchise history, the Rams entered the season as the defending Super Bowl champions. The Rams finished the regular-season with a record of 10–6 but would go on to lose to the New Orleans Saints 31–28 in the wild-card round of the playoffs. They led the NFL in scoring for a second straight year with 540 points. The Rams became the first team in NFL history to score more than 500 points on offense, while allowing more than 450 points on defense.
The 1999 St. Louis Rams season was the team's 62nd year with the National Football League (NFL) and the fifth season in St. Louis, Missouri. The Rams finished the regular-season with a record of 13–3, and defeated the Tennessee Titans in Super Bowl XXXIV.
The 2002 season was the Kansas City Chiefs' 33rd in the National Football League (NFL), their 43rd overall and the franchise's 40th in Kansas City, Missouri.
The 2001 season was the Kansas City Chiefs' 32nd in the National Football League (NFL) and their 42nd overall. It was their first year under head coach Dick Vermeil and 13th under general manager Carl Peterson. They finished the regular season with a 6–10 record.
The 1997 season was the Kansas City Chiefs' 28th in the National Football League (NFL) and their 38th overall. The Chiefs improved on their 9–7 record from 1996, and finished with a 13–3 record and as AFC West division champions. The Rich Gannon–Elvis Grbac quarterback controversy was a focal point of the team's season. It brewed throughout the entire season and arguably cost the Chiefs a victory in the playoffs. The Chiefs were defeated by division rival and eventual Super Bowl champion, Denver Broncos, in the 1997 playoffs. 1997 was the final season the Chiefs appeared in the playoffs during the 1990s and for the next several seasons, they fell into futility. They did not return to the playoffs until 2003.
The 2005 season was the New Orleans Saints' 39th in the National Football League (NFL) and the sixth and final under head coach Jim Haslett.
The 2011 season was the St. Louis Rams' 74th in the National Football League (NFL), their 17th in St. Louis, and their third and final season under head coach Steve Spagnuolo. They finished with a 2–14 record, a failure to improve on their 7–9 record from 2010. The day after the season finale, head coach Steve Spagnuolo and general manager Billy Devaney were fired from the team.
The 2012 season was the St. Louis Rams' 75th in the National Football League (NFL), their 18th in St. Louis and their first under head coach Jeff Fisher. Finishing at 7–8–1, they improved on their 2–14 record from 2011. In Week 10 against the San Francisco 49ers, the game ended in a 24–24 tie, the first since the 2008 NFL season. It was Sam Bradford's second and final full season as the Rams starting quarterback as two torn ACLs sidelined him for much of the next season and the entire 2014 season.
The 2013 Houston Texans season was the franchise's 12th season in the National Football League (NFL). The Texans failed to improve upon their 12–4 record from 2012, suffering through a season-ending 14-game losing streak following a 2–0 start and missing the playoffs for the first time since 2010. Head coach Gary Kubiak was fired after eight seasons following their eleventh loss. Defensive coordinator Wade Phillips was named the interim head coach for the final three games of the season. Out of the 14 games lost by the Texans this year, 9 of them were by one score, marking a record amount of one score losses for the franchise. Their 14-game losing streak is the worst in team history. Coming off a franchise-best 12–4 record just the year before, the Texans tie a league record with the Houston Oilers for the biggest season-to-season decline in win total. On January 3, 2014, claiming that "I'm ready to kick 2013 the hell out the door", Texans owner Robert McNair announced that former Penn State head coach Bill O'Brien would be the Texans' third head coach.
The 2013 Tennessee Titans season was the franchise's 44th season in the National Football League (NFL), the 54th overall, the 17th in the state of Tennessee and the third and final under head coach Mike Munchak. It was also the final season under the ownership of founder Bud Adams, who died on October 21. The Titans slightly improved on their 6–10 record from 2012 but missed the playoffs for a fifth consecutive season.
The 2013 season was the Dallas Cowboys' 54th in the National Football League (NFL), their fifth playing home games at AT&T Stadium and the third full season under head coach Jason Garrett. The Cowboys finished 8–8 for a third consecutive season, but missed the playoffs for a fourth consecutive season after losing their final game for the third straight season, this time to the Philadelphia Eagles.
The 2013 Atlanta Falcons season was the franchise's 48th season in the National Football League (NFL) and the sixth under head coach Mike Smith. The Falcons entered the season as one of the Super Bowl favorites; however, due to multiple key injuries to the team, the Falcons failed to improve on their 13–3 season from 2012, finishing 4-12. They did not qualify for postseason contention for the first time since 2009 and secured the Falcons’ first losing season since 2007.
The 2013 season was the New Orleans Saints' 47th in the National Football League (NFL) and their 38th playing home games at the Mercedes-Benz Superdome. It also marked the seventh season under head coach Sean Payton, who returned to the team after serving a one-year suspension for his involvement in the team's 2012 bounty scandal.
The 2014 season was the St. Louis Rams' 77th in the National Football League (NFL), their 20th in St. Louis and their third under head coach Jeff Fisher. The Rams attempted to reach a playoff berth for the first time since their 2004 season, but were officially eliminated in their loss against the Arizona Cardinals in Week 15. The Rams failed to improve on their 7–9 record from 2013, finishing 6–10 in 2014. The Rams' 2014 season was notable for their numerous starting quarterbacks including Austin Davis, Shaun Hill, and Sam Bradford, the last of whom was injured before the season began. Despite the lack of stability at the position, the Rams defeated both defending conference champions, Super Bowl participants, and 2014 division winners, the Seattle Seahawks and Denver Broncos, plus also shutting out two teams in consecutive weeks: the Oakland Raiders and Washington Redskins. This represents the most recent last-place finish in the NFC West for the St. Louis/Los Angeles Rams.
The 2014 season was the Arizona Cardinals' 95th in the National Football League (NFL), their 27th in Arizona and their second under head coach Bruce Arians. Following an explosive 9–1 start to the regular season, they finished at 11–5, achieving their highest win total since 1975 when they were still in St. Louis. The Cardinals clinched their first playoff berth since 2009, and had a chance to become the first team to try to play the Super Bowl on their own home field, University of Phoenix Stadium. However, after season-ending injuries to Carson Palmer and Drew Stanton, they were forced to start third-string quarterback Ryan Lindley in the wild-card round, losing to the Carolina Panthers, 27–16, which was the first time since 1982 when they were in St. Louis that the Cardinals went one-and-done.
The 2014 season was the New Orleans Saints' 48th in the National Football League (NFL), their 39th playing home games at the Mercedes-Benz Superdome and their eighth under head coach Sean Payton.
The 2015 season was the St. Louis Rams' 78th in the National Football League (NFL), their fourth under head coach Jeff Fisher, and their 21st and final season in St. Louis, Missouri, their home since the 1995 season.
The 2015 season was the New Orleans Saints' 49th in the National Football League (NFL), their 40th playing home games at the Mercedes-Benz Superdome and their ninth under head coach Sean Payton. On November 16, 2015, the Saints hired Dennis Allen to replace fired defensive coordinator Rob Ryan. However, the Saints still missed the playoffs for the second consecutive season. The Saints set a new league record for the most passing touchdowns allowed with 45.
The 2016 season was the New Orleans Saints' 50th in the National Football League (NFL), their 41st playing home games at the Mercedes-Benz Superdome, and their 10th under head coach Sean Payton. The Saints matched their 7–9 record from 2014 and 2015, and missed the playoffs for the third year in a row. One highlight from the season includes quarterback Drew Brees' first return to San Diego for the first time since the Chargers released him at the end of the 2005 season, also where Brees played his first five seasons in. This came 10 years after the Chargers released Brees after the Saints' previous regular season meetings with the Chargers were home games for the Saints, and including a 2008 meeting at Wembley Stadium in London, a game which New Orleans was designated as the home team.
The 2017 season was the New Orleans Saints' 51st in the National Football League (NFL), their 42nd playing home games at the Mercedes-Benz Superdome and their 11th under head coach Sean Payton. The team improved on their 7–9 output from the previous season, while achieving an eight-game winning streak after losing their first two contests, their longest streak since 2009, when they won Super Bowl XLIV. In Week 13 the Saints clinched their first winning season since 2013 and swept the Carolina Panthers for the first time since 2011. In Week 16, the Saints clinched a playoff spot for the first time since 2013 by defeating the Atlanta Falcons. In Week 17, the Saints clinched the NFC South for the first time since 2011 with the Panthers loss to the Falcons. This was the first of four consecutive NFC South titles for the Saints. On January 7, 2018 the Saints played their divisional rival Carolina Panthers in the playoffs for the first time in franchise history. They beat Carolina 31–26 in the Wild Card, but lost 29–24 to the Minnesota Vikings in the Divisional Round in a shocking ending.