| 4,4'-diapophytoene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.96 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
4,4'-diapophytoene synthase (EC 2.5.1.96, dehydrosqualene synthase, DAP synthase, C30 carotene synthase, CrtM) is an enzyme with systematic name farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase (4,4'-diapophytoene forming). [1] [2] [3] [4] This enzyme catalyses the following chemical reaction
- 2 (2E,6E)-farnesyl diphosphate 4,4'-diapophytoene + 2 diphosphate (overall reaction)
- (1a) 2 (2E,6E)-farnesyl diphosphate diphosphate + presqualene diphosphate
- (1b) presqualene diphosphate 4,4'-diapophytoene + diphosphate
This enzyme requires Mn2+. It is present in Staphylococcus aureus and some other bacteria such as Heliobacillus sp.
