4-hydroxybenzoate decarboxylase

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4-hydroxybenzoate decarboxylase
Identifiers
EC no. 4.1.1.61
CAS no. 37290-53-2
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The enzyme 4-hydroxybenzoate decarboxylase (EC 4.1.1.61) catalyzes the chemical reaction

4-hydroxybenzoate phenol + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxybenzoate carboxy-lyase (phenol-forming). Other names in common use include p-hydroxybenzoate decarboxylase, and 4-hydroxybenzoate carboxy-lyase. This enzyme participates in benzoate degradation via CoA ligation.

Related Research Articles

4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. 4-Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens, which are used as preservatives in cosmetics and some ophthalmic solutions. It is isomeric with 2-hydroxybenzoic acid, known as salicylic acid, a precursor to aspirin, and with 3-hydroxybenzoic acid.

Carboxy-lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds. These enzymes catalyze the decarboxylation of amino acids, beta-keto acids and alpha-keto acids.

The enzyme 3-oxolaurate decarboxylase (EC 4.1.1.56) catalyzes the chemical reaction

The enzyme 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) catalyzes the chemical reaction

The enzyme 4-hydroxyphenylacetate decarboxylase (EC 4.1.1.83) catalyzes the chemical reaction

The enzyme 4-oxalocrotonate decarboxylase (EC 4.1.1.77) catalyzes the chemical reaction

THe enzyme 6-methylsalicylate decarboxylase (EC 4.1.1.52) catalyzes the chemical reaction

The enzyme acetolactate decarboxylase (EC 4.1.1.5) catalyzes the chemical reaction

<span class="mw-page-title-main">Aminocarboxymuconate-semialdehyde decarboxylase</span>

The enzyme aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) catalyzes the chemical reaction

<span class="mw-page-title-main">Benzoylformate decarboxylase</span>

The enzyme benzoylformate decarboxylase (EC 4.1.1.7) catalyzes the following chemical reaction:

The enzyme gallate decarboxylase (EC 4.1.1.59) catalyzes the chemical reaction

The enzyme gentisate decarboxylase (EC 4.1.1.62) catalyzes the chemical reaction

In enzymology, a glutaconyl-CoA decarboxylase (EC 4.1.1.70) is an enzyme that catalyzes the chemical reaction

The enzyme o-pyrocatechuate decarboxylase (EC 4.1.1.46) catalyzes the chemical reaction

The enzyme orsellinate decarboxylase (EC 4.1.1.58) catalyzes the chemical reaction

<span class="mw-page-title-main">Oxalate decarboxylase</span>

In enzymology, an oxalate decarboxylase (EC 4.1.1.2) is an oxalate degrading enzyme that catalyzes the chemical reaction

The enzyme protocatechuate decarboxylase (EC 4.1.1.63) catalyzes the chemical reaction

<span class="mw-page-title-main">Sulfinoalanine decarboxylase</span>

The enzyme sulfinoalanine decarboxylase (EC 4.1.1.29) catalyzes the chemical reaction

The enzyme UDP-galacturonate decarboxylase (EC 4.1.1.67) catalyzes the chemical reaction

In enzymology, a phenacrylate decarboxylase (EC 4.1.1.102) is an enzyme that catalyzes the chemical reaction

References


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