ACER3

Last updated
ACER3
Identifiers
Aliases ACER3 , APHC, PHCA, alkaline ceramidase 3, PLDECO
External IDs OMIM: 617036 MGI: 1913440 HomoloGene: 5410 GeneCards: ACER3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300953
NM_001300954
NM_001300955
NM_018367

NM_025408

RefSeq (protein)

NP_001287882
NP_001287883
NP_001287884
NP_060837

NP_079684
NP_001347544
NP_001347545
NP_001347546

Location (UCSC) Chr 11: 76.86 – 77.03 Mb Chr 7: 98.21 – 98.32 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Alkaline ceramidase 3 also known as ACER3 is a ceramidase enzyme which in humans is encoded by the ACER3 gene. [5] [6]

Contents

Related Research Articles

Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).

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Neutral ceramidase is an enzyme that in humans is encoded by the ASAH2 gene.

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<span class="mw-page-title-main">SGPL1</span> Protein-coding gene in the species Homo sapiens

Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene.

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Ribosomal protein S6 kinase delta-1 is an enzyme that in humans is encoded by the RPS6KC1 gene.

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Ubiquitin carboxyl-terminal hydrolase 40 is an enzyme that in humans is encoded by the USP40 gene.

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N-acylethanolamine-hydrolyzing acid amidase is an enzyme that in humans is encoded by the NAAA gene.

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Ubiquitin carboxyl-terminal hydrolase 42 is an enzyme that in humans is encoded by the USP42 gene.

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CYP4X1 is a protein which in humans is encoded by the CYP4X1 gene.

<span class="mw-page-title-main">ACER1</span> Protein-coding gene in the species Homo sapiens

Alkaline ceramidase 1 also known as ACER1 is a ceramidase enzyme which in humans is encoded by the ACER1 gene.

<span class="mw-page-title-main">ACER2</span> Ceramidase enzyme

Alkaline ceramidase 2 also known as ACER2 is a ceramidase enzyme which in humans is encoded by the ACER2 gene.

<span class="mw-page-title-main">Tektin-1</span> Protein-coding gene in the species Homo sapiens

Tektin-1 is a protein that in humans is encoded by the TEKT1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000078124 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030760 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM (July 2001). "Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide". J. Biol. Chem. 276 (28): 26577–88. doi: 10.1074/jbc.M102818200 . PMID   11356846.
  6. Mao C, Obeid LM (September 2008). "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate". Biochim. Biophys. Acta. 1781 (9): 424–34. doi:10.1016/j.bbalip.2008.06.002. PMC   2614331 . PMID   18619555.

Further reading