Acetoin dehydrogenase

Acetoin dehydrogenase
Identifiers
EC no.	2.3.1.190
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Acetoin dehydrogenase (EC 2.3.1.190, acetoin dehydrogenase complex, acetoin dehydrogenase enzyme system, AoDH ES) is an enzyme with systematic name acetyl-CoA:acetoin O-acetyltransferase. ^{[1] [2] [3] [4] [5]} This enzyme catalyses the following chemical reaction

acetoin + CoA + NAD⁺${\displaystyle \rightleftharpoons }$ acetaldehyde + acetyl-CoA + NADH + H⁺

This enzyme requires thiamine diphosphate.

See also

• Diacetyl reductase

References

1. Priefert H, Hein S, Krüger N, Zeh K, Schmidt B, Steinbüchel A (July 1991). "Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism". Journal of Bacteriology. 173 (13): 4056–71. doi:10.1128/jb.173.13.4056-4071.1991. PMC   208054 . PMID   2061286.
2. Oppermann FB, Steinbüchel A (January 1994). "Identification and molecular characterization of the aco genes encoding the Pelobacter carbinolicus acetoin dehydrogenase enzyme system". Journal of Bacteriology. 176 (2): 469–85. doi:10.1128/jb.176.2.469-485.1994. PMC   205071 . PMID   8110297.
3. Krüger N, Oppermann FB, Lorenzl H, Steinbüchel A (June 1994). "Biochemical and molecular characterization of the Clostridium magnum acetoin dehydrogenase enzyme system". Journal of Bacteriology. 176 (12): 3614–30. doi:10.1128/jb.176.12.3614-3630.1994. PMC   205551 . PMID   8206840.
4. Huang M, Oppermann FB, Steinbüchel A (December 1994). "Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway". FEMS Microbiology Letters. 124 (2): 141–50. doi: 10.1111/j.1574-6968.1994.tb07276.x . PMID   7813883.
5. Huang M, Oppermann-Sanio FB, Steinbüchel A (June 1999). "Biochemical and molecular characterization of the Bacillus subtilis acetoin catabolic pathway". Journal of Bacteriology. 181 (12): 3837–41. doi:10.1128/JB.181.12.3837-3841.1999. PMC   93865 . PMID   10368162.

External links

• Acetoin+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)