All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific)

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All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific)
Identifiers
EC no. 2.5.1.84
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All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) (EC 2.5.1.84, nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, SolPP synthase, SPP-synthase, SPP synthase, solanesyl-diphosphate synthase, OsSPS2) is an enzyme with systematic name geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units). [1] [2] [3] [4] [5] [6] This enzyme catalyses the following chemical reaction

geranyl diphosphate + 7 isopentenyl diphosphate 7 diphosphate + all-trans-nonaprenyl diphosphate

This enzyme is involved in the synthesis of the side chain of menaquinone-9.

Related Research Articles

Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as sterols and carotenoids. It is also used in the synthesis of CoQ, as well as dehydrodolichol diphosphate.

<span class="mw-page-title-main">Isopentenyl-diphosphate delta isomerase</span> Class of enzymes

Isopentenyl pyrophosphate isomerase, also known as Isopentenyl-diphosphate delta isomerase, is an isomerase that catalyzes the conversion of the relatively un-reactive isopentenyl pyrophosphate (IPP) to the more-reactive electrophile dimethylallyl pyrophosphate (DMAPP). This isomerization is a key step in the biosynthesis of isoprenoids through the mevalonate pathway and the MEP pathway.

<span class="mw-page-title-main">Dimethylallyltranstransferase</span> Mammalian protein found in Homo sapiens

Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene and catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).

<span class="mw-page-title-main">Prenyltransferase</span>

Prenyltransferases (PTs) are a class of enzymes that transfer allylic prenyl groups to acceptor molecules. Prenyl transferases commonly refer to isoprenyl diphosphate syntheses (IPPSs). Prenyltransferases are a functional category and include several enzyme groups that are evolutionarily independent.

<span class="mw-page-title-main">Bornyl diphosphate synthase</span>

In enzymology, bornyl diphosphate synthase (BPPS) (EC 5.5.1.8) is an enzyme that catalyzes the chemical reaction

In enzymology, a di-trans,poly-cis-decaprenylcistransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a farnesyltranstransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a geranyltranstransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a heptaprenyl diphosphate synthase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">GGPS1</span> Mammalian protein found in Homo sapiens

Geranylgeranyl pyrophosphate synthase is an enzyme that in humans is encoded by the GGPS1 gene.

TRNA dimethylallyltransferase is an enzyme with systematic name dimethylallyl-diphosphate: tRNA dimethylallyltransferase. This enzyme catalyses the following chemical reaction

Geranylfarnesyl diphosphate synthase is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase . This enzyme catalyses the following chemical reaction

Hexaprenyl diphosphate synthase is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase . This enzyme catalyses the following chemical reaction

Hexaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

All-trans-nonaprenyl diphosphate synthase is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase . This enzyme catalyses the following chemical reaction

Trans,polycis-polyprenyl diphosphate synthase is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction

<span class="mw-page-title-main">All-trans-octaprenyl-diphosphate synthase</span> Class of enzymes

All-trans-octaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

All-trans-decaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

<span class="mw-page-title-main">1,8-cineole synthase</span>

1,8-Cineole synthase (EC 4.2.3.108, 1,8-cineole cyclase, geranyl pyrophoshate:1,8-cineole cyclase, 1,8-cineole synthetase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, 1,8-cineole-forming). This enzyme catalyses the following chemical reaction

(+)-α-pinene synthase is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-α-pinene-forming]. This enzyme catalyses the following chemical reaction

References

  1. ↑ Sagami H, Ogura K, Seto S (October 1977). "Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus". Biochemistry. 16 (21): 4616–22. doi:10.1021/bi00640a014. PMID   911777.
  2. ↑ Fujii H, Sagami H, Koyama T, Ogura K, Seto S, Baba T, Allen CM (October 1980). "Variable product specificity of solanesyl pyrophosphate synthetase". Biochemical and Biophysical Research Communications. 96 (4): 1648–53. doi:10.1016/0006-291X(80)91363-7. PMID   7447947.
  3. ↑ Ohara K, Sasaki K, Yazaki K (June 2010). "Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa". Journal of Experimental Botany. 61 (10): 2683–92. doi:10.1093/jxb/erq103. PMC   2882263 . PMID   20421194.
  4. ↑ Ohnuma S, Koyama T, Ogura K (December 1991). "Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase". The Journal of Biological Chemistry. 266 (35): 23706–13. PMID   1748647.
  5. ↑ Gotoh T, Koyama T, Ogura K (July 1992). "Farnesyl diphosphate synthase and solanesyl diphosphate synthase reactions of diphosphate-modified allylic analogs: the significance of the diphosphate linkage involved in the allylic substrates for prenyltransferase". Journal of Biochemistry. 112 (1): 20–7. PMID   1429508.
  6. ↑ Teclebrhan H, Olsson J, Swiezewska E, Dallner G (November 1993). "Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes". The Journal of Biological Chemistry. 268 (31): 23081–6. PMID   8226825.
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