Anopheles stephensi

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Anopheles stephensi
Anopheles stephensi.jpeg
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Domain: Eukaryota
Kingdom: Animalia
Phylum: Arthropoda
Class: Insecta
Order: Diptera
Family: Culicidae
Genus: Anopheles
Species:
A. stephensi
Binomial name
Anopheles stephensi
Liston, 1901

Anopheles stephensi is a primary mosquito vector of malaria in urban India and is included in the same subgenus as Anopheles gambiae , the primary malaria vector in Africa. [1] A. gambiae consists of a complex of morphologically identical species of mosquitoes, along with all other major malaria vectors; however, A. stephensi has not yet been included in any of these complexes. [2] Nevertheless, two races of A. stephensi exist based on differences in egg dimensions and the number of ridges on the eggs; A. s. stephensisensu stricto, the type form, is a competent malaria vector that takes place in urban areas, and A. s. mysorensis, the variety form, exists in rural areas and exhibits considerable zoophilic behaviour, making it a poor malaria vector. [3] However, A. s. mysorensis is a detrimental vector in Iran. [4] An intermediate form also exists in rural communities and peri-urban areas, though its vector status is unknown. [4] About 12% of malaria cases in India are due to A. stephensi. [5]

Contents

In November 2015, an American research group demonstrated that an A. stephensi with genetic modifications could be rendered incapable of transmitting malaria, and that 99.5% of the mutant mosquitoes' offspring were also immune. [6]

In April of 2023, a malaria outbreak at Dire Dawa University in Ethiopia affected 1,300 students. The outbreak was a mystery because it occurred in the dry season and in an urban area, both atypical conditions for common cases of malaria in this area of the world. Blood tests confirming malaria's ring-shaped parasite ultimately led researchers to conclude that it was the work of A. stephensi, which thrives in urban areas and dry seasons, and has a resistance to insecticides. [7]

A team of scientists, headed by an entomologist from the University of Oxford, conducted an evaluation of Africa's environments to determine if they provide suitable conditions for the A. stephensi mosquito. Their findings indicate that the ongoing spread of this species could potentially expose an additional 126 million persons to the risk of malaria. [7]

Habitat

In rural areas, the larvae of A. stephensi may exist in many aquatic habitats, such as ponds, streams, swamps, marshes, and other sources of standing water. [8] They may also occupy smaller environments, such as tree holes, leaf axils, and man-made containers. [9] The larvae of A. s. mysorensis exclusively prefer to occupy stone pots and earthenware containers. [4] This species is also able to endure high levels of salinity, and have been found to breed readily in water where the salinity is equal to or even surpassing that of sea water. [10] Furthermore, A. stephensi breeds in a number of different water-bodies in urban areas, but predominantly in artificial containers, walls, overhead tanks, and ground level water tanks. [11]

Most larvae feed on microorganisms and particle matter suspended in water. [9] However, later in development, adult males feed on the nectar of flowers, whereas females take blood meals, which help produce viable eggs. [3]

Hosts

Hosts include Bos taurus , Mus musculus and Pimephales promelas . [12]

Parasites

A. stephensi is a vector of bovine leukemia virus [12] and Plasmodium berghei . [13] Mack and Vandenberg performed a series of experiments 1978-1979 finding that P. berghei derives nutrients from A. stephensi hemolymph during the sporogonic phase. [13] A. stephensi is an important vector for the human malaria species Plasmodium falciparum . [14]

Biochemistry

Mack and Vandenberg characterized A. stephensi's hemolymph composition in the late 1970s. [13]

Distribution

A. stephensi is a subtropical species that predominates in the Indian subcontinent (except Nepal and Sri Lanka) [3] and is also distributed across the Middle East and South Asia region, existing in countries such as: Afghanistan, Bahrain, Bangladesh, China, Egypt, India, Iran, Iraq, Oman, Pakistan, Saudi Arabia, and Thailand. [2] A. stephensi was discovered to be established on the continent of Africa, in Djibouti on the Horn of Africa in 2012 [15] or 2013, [16] in 2016 in Ethiopia, [17] [15] Sri Lanka in 2017, [15] and in 2019 in the Republic of the Sudan/North Sudan. [15]

Seasonal activity

A. stephensi is considered to be endophilic and endophagic, regardless that it may feed outdoors during the summer, when weather is warmer and humans and animals are more likely to sleep outside in the open air. [10] Although indoor feeding habits have shown no variation between seasons, adult females tend to feed more often at night during the summer rather than during the day in winter. [4] A. stephensi shows a greater preference for humans over animals in urban areas, where they can be found year-round. [4]

Insecticide resistance

The introduced African population appears to have arrived with several insecticide resistances. [15]

Related Research Articles

<span class="mw-page-title-main">Mosquito</span> Family of flies

Mosquitoes, the Culicidae, are a family of small flies consisting of 3,600 species. The word "mosquito" is Spanish for "little fly". Mosquitoes have a slender segmented body, one pair of wings, three pairs of long hair-like legs, and specialized, highly elongated, piercing-sucking mouthparts. All mosquitoes drink nectar from flowers; females of some species have in addition adapted to drink blood. Evolutionary biologists view mosquitoes as micropredators, small animals that parasitise larger ones by drinking their blood without immediately killing them. Medical parasitologists view mosquitoes instead as vectors of disease, carrying protozoan parasites or bacterial or viral pathogens from one host to another.

<i>Anopheles</i> Genus of mosquito

Anopheles is a genus of mosquito first described by J. W. Meigen in 1818. Its members are sometimes called nail mosquitoes or marsh mosquitoes. Many are vectors of the parasite Plasmodium, which causes malaria in birds, reptiles, and mammals including humans. Anopheles gambiae is the best-known species, as it transmits one of the most dangerous human malarial parasites, Plasmodium falciparum. No other mosquito genus is a vector of human malaria.

<i>Plasmodium berghei</i> Single celled parasite, rodent malaria

Plasmodium berghei is a single-celled parasite causing rodent malaria. It is in the Plasmodium subgenus Vinckeia.

<i>Anopheles gambiae</i> Species of mosquito

The Anopheles gambiae complex consists of at least seven morphologically indistinguishable species of mosquitoes in the genus Anopheles. The complex was recognised in the 1960s and includes the most important vectors of malaria in sub-Saharan Africa, particularly of the most dangerous malaria parasite, Plasmodium falciparum. It is one of the most efficient malaria vectors known. The An. gambiae mosquito additionally transmits Wuchereria bancrofti which causes lymphatic filariasis, a symptom of which is elephantiasis.

<i>Culex tritaeniorhynchus</i> Species of fly

Culex (Culex) tritaeniorhynchus is a species of mosquito and is the main vector of the disease Japanese encephalitis. This mosquito is a native of northern Asia, and parts of Africa. Females target large animals for blood extraction, including cattle and swine, and are strongly anthropophilic.

<i>Anopheles culicifacies</i> Species of mosquito

Anopheles culicifacies is a mosquito species complex and one of the primary vectors of malaria on the Indian subcontinent. It consists of five sibling species, provisionally designated as species A, B, C, D, and E. It prefers to rest indoors in cattle sheds, where it feeds on cattle. The control of A. culicifacies has become difficult due to the development of insecticide resistance against all commonly used insecticides, including new-generation insecticides such as synthetic pyrethroids.

<i>Mkilua</i> Species of plant in the family Annonaceae

Mkilua is a genus of plant in the family Annonaceae. It is native to Kenya and Tanzania. It contains a single species, Mkilua fragrans. Bernard Verdcourt, the British botanist who first formally described the species, named it after the fragrance of its flowers which smell like lemon. It is commonly called Mkilua Mwitu, Kilua and Kiluwa in Swahili, and Kingade in Digo. Volatile oils extracted from its leaves, flowers, and aerial parts have been reported to be repellent to Anopheles gambiae mosquitoes which are vectors for the malaria parasite Plasmodium falciparum. Bioactive molecules extracted from its roots have been reported to have antimicrobial activity in tests with Streptococcus agalactiae and Staphylococcus aureus.

<i>Culex restuans</i> Species of fly

Culex restuans is a species of mosquito known to occur in Canada, the United States, Mexico, Guatemala, Honduras, and the Bahamas. It is a disease vector for St. Louis encephalitis and West Nile virus. In 2013 West Nile Virus positive specimens were collected in Southern California.

Taxonomy of <i>Anopheles</i> Genus of flies

Anopheles is a genus of mosquitoes (Culicidae) with about 484 recognised species.

<i>Anopheles albimanus</i> Species of mosquito

Anopheles albimanus is a species of mosquito in the order Diptera. It is found in coastal Central and South America, the Caribbean, and Mexico. It is a generalist species and capable of wide dispersion. A. albimanus is a common malaria vector.

<i>Anopheles claviger</i> Species of mosquito

Anopheles claviger is a mosquito species found in Palearctic realm covering Europe, North Africa, northern Arabian Peninsula, and northern Asia. It is responsible for transmitting malaria in some of these regions. The mosquito is made up of a species complex consisting of An. claviger sensu stricto and An. petragnani Del Vecchio. An. petragnani is found only in western Mediterranean region, and is reported to bite only animals; hence, it is not involved in human malaria.

<i>Anopheles sinensis</i> Species of mosquito

Anopheles sinensis is a species of mosquito that transmits malaria as well as lymphatic filariasis. It is regarded as the most important vector of these human parasitic diseases in Southeast Asia. It is the primary vector of vivax malaria in many regions. In China it also transmits the filalarial parasite, and arthropod roundworm. In Japan it is also a vector of a roundworm Setaria digitata in sheep and goats.

Anopheles nili is a species of mosquito in the Culicidae family. It comprises the following elements: An. carnevalei, An. nili, An. ovengensis and An. somalicus. The scientific name of this species was first published in 1904 by Theobald. It is the main mosquito species found in the south Cameroon forest zone which bites humans. It is known as a problematic carrier of malaria, although newly discovered, closely related species in the same genus have also been found to interact with A. nili as a disease vector. In that, they both have similar feeding habits on local targets in the Cameroon region.

Elizabethkingia anophelis is a yellow-pigmented, rod-shaped, gram-negative bacterium in the Flavobacteriaceae family. Elizabethkingia is isolated from the midgut of Anopheles gambiae G3 mosquitoes reared in captivity. The genus Elizabethkingia, named for former US Centers for Disease Control and Prevention (CDC) microbiologist Elizabeth O. King, also includes E. meningoseptica which causes neonatal sepsis and infections in immunocompromised persons, E. endophytica, and E. miricola.

Anopheles (Cellia) vagus is a species complex of zoophilic mosquito belonging to the genus Anopheles. It is found in India, Sri Lanka and Indonesia. It is a potential natural vector of malarial parasite Plasmodium falciparum, and Japanese encephalitis virus. It is highly susceptible to insecticide deltamethrin and resistant to DDT.

<i>Toxorhynchites splendens</i> Species of fly

Toxorhynchites (Toxorhynchites) splendens is a species of non-hematophagous mosquito belonging to the genus Toxorhynchites. It is widely used as a predator to control dengue mosquitoes.

<i>Anopheles freeborni</i> Species of Mosquito

Anopheles freeborni, commonly known as the western malaria mosquito, is a species of mosquito in the family Culicidae. It is typically found in the western United States and Canada. Adults are brown to black, with yellow-brown hairs and gray-brown stripes on the thorax. Their scaly wings have four dark spots, which are less distinct in the male.

<i>Anopheles atroparvus</i> Palearctic mosquito species

Anopheles atroparvus is a European species of mosquito, which was first identified in 1927. It is one of the most abundant palearctic Anopheles species belonging to the family Culicidae, commonly called mosquitoes. Although research interest in A. atroparvus has been low in the past several decades, recent concern for an increase in vector-borne disease has encouraged new research into this species.

<i>Anopheles arabiensis</i> African mosquito and disease vector

Anopheles arabiensis is a zoophilic species of mosquito and a vector of disease endemic to Africa.

Anopheles cruzii, is the species of mosquito that mainly located in southern coast of Brazil, is main vector of malaria, Plasmodium vivax.

References

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Further reading