Mitochondrial trifunctional protein (MTP) is a protein attached to the inner mitochondrial membrane which catalyzes three out of the four steps in beta oxidation. MTP is a hetero-octamer composed of four alpha and four beta subunits:
Deoxycytidine diphosphate is a nucleoside diphosphate. It is related to the common nucleic acid CTP, or cytidine triphosphate, with the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose removed, and with one fewer phosphoryl group than CTP.
Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant and in the plasma membrane where it directly activates lipid-gated ion channels.
Diglyceride acyltransferase, DGAT, catalyzes the formation of triglycerides (triacylglycerols) from diacylglycerol and acyl-CoA. The reaction catalyzed by DGAT is considered the terminal and only committed step in the acyl-CoA-dependent triglyceride synthesis, universally important in animal, plants, and microorganisms. The conversion is essential for intestinal absorption and adipose tissue formation in mammalian. DGAT1 are homologous to other membrane-bound O-acyltransferases, but not all other DGATs.
The enzyme CDP-glucose 4,6-dehydratase (EC 4.2.1.45) catalyzes the chemical reaction
In enzymology, a CDP-diacylglycerol diphosphatase (EC 3.6.1.26) is an enzyme that catalyzes the chemical reaction
Butyryl-CoA is an organic coenzyme A-containing derivative of butyric acid. It is a natural product found in many biological pathways, such as fatty acid metabolism, fermentation, and 4-aminobutanoate (GABA) degradation. It mostly participates as an intermediate, a precursor to and converted from crotonyl-CoA. This interconversion is mediated by butyryl-CoA dehydrogenase.
In enzymology, a 2-acylglycerol O-acyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a glycerol-3-phosphate O-acyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a CDP-diacylglycerol—inositol 3-phosphatidyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a CDP-diacylglycerol—serine O-phosphatidyltransferase is an enzyme that catalyzes the chemical reaction
Choline-phosphate cytidylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an ethanolaminephosphotransferase is an enzyme that catalyzes the chemical reaction
Phosphatidate cytidylyltransferase (CDS) is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from cytidine triphosphate and phosphatidate.
Sterol O-acyltransferase 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene.
2-Acylglycerol O-acyltransferase 2 also known as acyl-CoA:monoacylglycerol acyltransferase 2 (MGAT2) or Diacylglycerol O-acyltransferase candidate 5 (DC5) is an enzyme that in humans is encoded by the MOGAT2 gene.
Cytidine diphosphate glucose, often abbreviated CDP-glucose, is a nucleotide-linked sugar consisting of cytidine diphosphate and glucose. This nucleotide saccharide participates in the synthesis of deoxy sugars such as paratose and tyvelose.
Monolysocardiolipin (MLCL) is a phospholipid with three fatty acid chains located in the inner membrane of mitochondria.
Monoacylglycerol O-acyltransferase 3 is a protein that in humans is encoded by the MOGAT3 gene.
The PI(4,5)P2 cycle or simply PIP2 cycle (also known as PI cycle in past) is one of the important signalling cascades underlying many cellular functions including GPCR signaling, cytokinesis, endocytosis, and apoptosis.
