Caetano Reis e Sousa

In this Portuguese name, the first or maternal family name is Pacheco Paisand the second or paternal family name is dos Reis e Sousa.

Caetano Reis e Sousa FRS FMedSci
Born	Caetano Maria Pacheco Pais dos Reis e Sousa 1968 (age 56–57) [1] Lisbon, Portugal [1]
Education	Atlantic College
Alma mater	Imperial College London (BSc) University of Oxford (DPhil)
Awards	EMBO Member (2006) [2] Louis-Jeantet Prize for Medicine (2017)
Scientific career
Fields	Immunology [3]
Institutions	Francis Crick Institute Imperial College London Imperial Cancer Research Fund National Institute of Allergy and Infectious Diseases
Thesis	Phagocytosis of antigens by Langerhans cells
Doctoral advisor	Jonathan Austyn
Website	www.crick.ac.uk/research/labs/caetano-reis-e-sousa

Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968) ^[1] is a Portuguese scientist who is a principal group leader at the Francis Crick Institute ^{[3] [4] [5] [6]} .

Education

Reis e Sousa was educated at Atlantic College in Wales, ^[6] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells, and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn. ^[7]

Career and research

After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain, he joined the Imperial Cancer Research Fund (ICRF) in 1998. ^[8] He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015. ^[8] He is also a visiting professor of Immunology at Imperial College London ^{[9] [10]} and King's College London and honorary professor at University College London (UCL).

Reis e Sousa's research centres on the mechanisms involved in sensing infection, cancer and tissue injury. ^[8] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses, fungi and dead cells. ^{[8] [11] [12] [13]}

Awards and honours

Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO) ^[2] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009. ^[8] He was awarded the Liliane Bettencourt for Life Sciences Prize in 2008, Louis-Jeantet Prize for Medicine in 2017 ^[1] and the Bial Award in Biomedicine in 2019.

References

1. "Caetano REIS E SOUSA". jeantet.ch. 4 October 2017.
2. Anon (2006). "Caetano Reis e Sousa". people.embo.org. European Molecular Biology Organization.
3. Caetano Reis e Sousa publications indexed by Google Scholar
4. "Caetano Reis e Sousa: Immunobiology Laboratory". crick.ac.uk.
5. "Researchers: Caetano Reis e Sousa". crick.ac.uk.
6. Bashyam, Hema (2008). "Caetano Reis e Sousa: harnessing DC power". The Journal of Experimental Medicine. 205 (9): 1946–1947. doi:10.1084/jem.2059pi. ISSN   0022-1007. PMC   2526189 . PMID   18762569.
7. Reis e Sousa, Caetano Maria Pacheco Pais dos (1992). Phagocytosis of antigens by Langerhans cells (DPhil thesis). University of Oxford. OCLC   863542179. EThOS   uk.bl.ethos.314901.
8. Anon (2019). "Professor Caetano Reis e Sousa FMedSci FRS". royalsociety.org. London: Royal Society. Archived from the original on 24 April 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

   "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)

9. Caetano Reis e Sousa publications from Europe PubMed Central
10. "Professor Caetano Reis e Sousa". Imperial College London.
11. Diebold, S. S. (2004). "Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA". Science. 303 (5663): 1529–1531. Bibcode:2004Sci...303.1529D. doi: 10.1126/science.1093616 . ISSN   0036-8075. PMID   14976261. S2CID   33144196.
12. Kato, Hiroki; Takeuchi, Osamu; Sato, Shintaro; Yoneyama, Mitsutoshi; Yamamoto, Masahiro; Matsui, Kosuke; Uematsu, Satoshi; Jung, Andreas; Kawai, Taro; Ishii, Ken J.; Yamaguchi, Osamu; Otsu, Kinya; Tsujimura, Tohru; Koh, Chang-Sung; Reis e Sousa, Caetano; Matsuura, Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature. 441 (7089): 101–105. Bibcode:2006Natur.441..101K. doi:10.1038/nature04734. ISSN   0028-0836. PMID   16625202. S2CID   2270879.
13. Pichlmair, A.; Schulz, O.; Tan, C. P.; Naslund, T. I.; Liljestrom, P.; Weber, F.; Reis e Sousa, C. (2006). "RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates". Science. 314 (5801): 997–1001. Bibcode:2006Sci...314..997P. doi: 10.1126/science.1132998 . ISSN   0036-8075. PMID   17038589. S2CID   44366096.