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Radon is a chemical element; it has symbol Rn and atomic number 86. It is a radioactive noble gas and is colorless and odorless. Of the three naturally occurring radon isotopes, only 222Rn has a sufficiently long half-life for it to be released from the soil and rock where it is generated. Radon isotopes are the immediate decay products of radium isotopes. The instability of 222Rn, its most stable isotope, makes radon one of the rarest elements. Radon will be present on Earth for several billion more years despite its short half-life, because it is constantly being produced as a step in the decay chains of 238U and 232Th, both of which are abundant radioactive nuclides with half-lives of at least several billion years. The decay of radon produces many other short-lived nuclides, known as "radon daughters", ending at stable isotopes of lead. 222Rn occurs in significant quantities as a step in the normal radioactive decay chain of 238U, also known as the uranium series, which slowly decays into a variety of radioactive nuclides and eventually decays into stable 206Pb. 220Rn occurs in minute quantities as an intermediate step in the decay chain of 232Th, also known as the thorium series, which eventually decays into stable 208Pb.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans.
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Passive smoking is the inhalation of tobacco smoke, called passive smoke, secondhand smoke (SHS) or environmental tobacco smoke (ETS), by individuals other than the active smoker. It occurs when tobacco smoke diffuses into the surrounding atmosphere as an aerosol pollutant, which leads to its inhalation by nearby bystanders within the same environment. Exposure to secondhand tobacco smoke causes many of the same health effects caused by active smoking, although at a lower prevalence due to the reduced concentration of smoke that enters the airway.
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Tobacco products, especially when smoked or used orally, have serious negative effects on human health. Smoking and smokeless tobacco use are the single greatest causes of preventable death globally. Half of tobacco users die from complications related to such use. Current smokers are estimated to die an average of 10 years earlier than non-smokers. The World Health Organization estimates that, in total, about 8 million people die from tobacco-related causes, including 1.3 million non-smokers due to secondhand smoke. It is further estimated to have caused 100 million deaths in the 20th century.
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Francine Laden is an American epidemiologist who is Professor of Environmental Epidemiology at the Harvard T.H. Chan School of Public Health. Her research has investigated the environmental epidemiology of chronic disease. She serves as co-director of the Harvard University and Boston University center for research on environmental and social stressors in housing across the life course. Laden has also served on the United States Environmental Protection Agency advisory board.
References
- ↑ "UK Health Protection Agency entry". hpa.org.uk. Archived from the original on 2006-11-27.
- ↑ Darby, S. C.; Whitely, E.; Howe, G. R.; Hutchings, S. J.; Kusiak, R. A.; Lubin, J. H.; Morrison, H. I.; Tirmarche, M.; Tomasek, L.; Radford, E. P.; Roscoe, R. J.; Samet, J. M.; Yao, S. X. (1995). "Radon and Cancers Other Than Lung Cancer in Underground Miners: a Collaborative Analysis of 11 Studies". JNCI Journal of the National Cancer Institute. 87 (5): 378–384. doi:10.1093/jnci/87.5.378. ISSN 0027-8874. PMID 7853419.
- ↑ Sarah Darby publications from Europe PubMed Central
- ↑ Darby, Sarah C; Ewart, David W; Giangrande, Paul LF; Spooner, Rosemary JD; Rizza, Charles R; Dusheiko, Geoffrey M; Lee, Christine A; Ludlam, Christopher A; Preston, F Eric (1997). "Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C". The Lancet. 350 (9089): 1425–1431. doi:10.1016/S0140-6736(97)05413-5. ISSN 0140-6736. PMID 9371165. S2CID 20692603.
- ↑ Darby, Sarah C.; Kan, Sau Wan; Spooner, Rosemary J.; Giangrande, Paul L. F.; Hill, Frank G. H.; Hay, Charles R. M.; Lee, Christine A.; Ludlam, Christopher A.; Williams, Michael (2007). "Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV". Blood. 110 (3): 815–825. doi: 10.1182/blood-2006-10-050435 . ISSN 0006-4971. PMID 17446349.
- 1 2 3 4 5 6 7 Anon (2019). "Sarah Darby". royalsociety.org. London: Royal Society. Archived from the original on 2019-04-24. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
- ↑ Darby, Sarah C. (1977). A Bayesian Approach to Parallel Line Bioassay. jisc.ac.uk (PhD thesis). London School of Hygiene and Tropical Medicine (University of London). OCLC 1124248683. EThOS uk.bl.ethos.452976.
- ↑ Darby, Sarah C.; Ewertz, Marianne; McGale, Paul; Bennet, Anna M.; Blom-Goldman, Ulla; Brønnum, Dorthe; Correa, Candace; Cutter, David; Gagliardi, Giovanna; Gigante, Bruna; Jensen, Maj-Britt; Nisbet, Andrew; Peto, Richard; Rahimi, Kazem; Taylor, Carolyn; Hall, Per (2013). "Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer" (PDF). New England Journal of Medicine. 368 (11): 987–998. doi:10.1056/NEJMoa1209825. hdl:10616/41712. ISSN 0028-4793. PMID 23484825. S2CID 31409740.
- ↑ Darby, Sarah C; McGale, Paul; Taylor, Carolyn W; Peto, Richard (2005). "Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300 000 women in US SEER cancer registries". The Lancet Oncology. 6 (8): 557–565. doi:10.1016/S1470-2045(05)70251-5. ISSN 1470-2045. PMID 16054566.
- ↑ Mathews, J. D.; Forsythe, A. V.; Brady, Z.; Butler, M. W.; Goergen, S. K.; Byrnes, G. B.; Giles, G. G.; Wallace, A. B.; Anderson, P. R.; Guiver, T. A.; McGale, P.; Cain, T. M.; Dowty, J. G.; Bickerstaffe, A. C.; Darby, S. C. (2013). "Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians". BMJ. 346 (1): f2360. doi:10.1136/bmj.f2360. ISSN 1756-1833. PMC 3660619 . PMID 23694687.
- ↑ Royal Statistical Society Guy Medal in Bronze, MacTutor History of Mathematics Archive
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