Cloaca | |
---|---|
Details | |
Days | 15 |
Precursor | endoderm [1] |
Gives rise to | Urogenital sinus (anteriorly) and Anorectal canal (posteriorly) |
Identifiers | |
MeSH | D002988 |
TE | (embryology)_by_E5.4.0.0.0.0.14 E5.4.0.0.0.0.14 |
Anatomical terminology |
The cloaca (pl.: cloacae) is a structure in the development of the urinary and reproductive organs.
The hind-gut is at first prolonged backward into the body-stalk as the tube of the allantois; but, with the growth and flexure of the tail-end of the embryo, the body-stalk, with its contained allantoic tube, is carried forward to the ventral aspect of the body, and consequently a bend is formed at the junction of the hind-gut and allantois.
This bend becomes dilated into a pouch, which constitutes the endodermal cloaca; into its dorsal part the hind-gut opens, and from its ventral part the allantois passes forward.
At a later stage, the Wolffian duct and Müllerian duct open into its ventral portion.
The cloaca is, for a time, shut off from the anterior by the cloacal membrane, formed by the apposition of the ectoderm and endoderm, and reaching, at first, as far forward as the future umbilicus.
Behind the umbilicus, however, the mesoderm subsequently extends to form the lower part of the abdominal wall and pubic symphysis.
By the growth of the surrounding tissues, the cloacal membrane comes to lie at the bottom of a depression, which is lined by ectoderm and named the ectodermal cloaca.
A birth defect can arise known as a persistent cloaca where the rectum, vagina, and urinary tract fuse to create a common channel or cloaca.
A rare birth defect which leaves much of the abdominal organs exposed is known as cloacal exstrophy. [2]
The bladder is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical adult human bladder will hold between 300 and 500 ml before the urge to empty occurs, but can hold considerably more.
The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.
A body cavity is any space or compartment, or potential space, in an animal body Cavities accommodate organs and other structures; cavities as potential spaces contain fluid.
The amnion is a membrane that closely covers the human and various other embryos when first formed. It fills with amniotic fluid, which causes the amnion to expand and become the amniotic sac that provides a protective environment for the developing embryo. The amnion, along with the chorion, the yolk sac and the allantois protect the embryo. In birds, reptiles and monotremes, the protective sac is enclosed in a shell. In marsupials and placental mammals, it is enclosed in a uterus.
The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that plays a critical role in the formation of male reproductive organs. The duct is named after Caspar Friedrich Wolff, a German physiologist and embryologist who first described it in 1759.
In the anatomy of some animals, a cloaca, pl.: cloacae, is the rear orifice that serves as the only opening for the digestive, reproductive, and urinary tracts of many vertebrate animals. All amphibians, reptiles, birds, and a few mammals, have this orifice, from which they excrete both urine and feces; this is in contrast to most placental mammals, which have two or three separate orifices for evacuation. Excretory openings with analogous purpose in some invertebrates are also sometimes called cloacae. Mating through the cloaca is called cloacal copulation and cloacal kissing.
Omphalocele or omphalocoele also called exomphalos, is a rare abdominal wall defect. Beginning at the 6th week of development, rapid elongation of the gut and increased liver size reduces intra abdominal space, which pushes intestinal loops out of the abdominal cavity. Around 10th week, the intestine returns to the abdominal cavity and the process is completed by the 12th week. Persistence of intestine or the presence of other abdominal viscera in the umbilical cord results in an omphalocele.
The allantois is a hollow sac-like structure filled with clear fluid that forms part of a developing amniote's conceptus. It helps the embryo exchange gases and handle liquid waste.
The yolk sac is a membranous sac attached to an embryo, formed by cells of the hypoblast layer of the bilaminar embryonic disc. This is alternatively called the umbilical vesicle by the Terminologia Embryologica (TE), though yolk sac is far more widely used. In humans, the yolk sac is important in early embryonic blood supply, and much of it is incorporated into the primordial gut during the fourth week of embryonic development.
The development of the urinary system begins during prenatal development, and relates to the development of the urogenital system – both the organs of the urinary system and the sex organs of the reproductive system. The development continues as a part of sexual differentiation.
The male reproductive system consists of a number of sex organs that play a role in the process of human reproduction. These organs are located on the outside of the body, and within the pelvis.
The foregut in humans is the anterior part of the alimentary canal, from the distal esophagus to the first half of the duodenum, at the entrance of the bile duct. Beyond the stomach, the foregut is attached to the abdominal walls by mesentery. The foregut arises from the endoderm, developing from the folding primitive gut, and is developmentally distinct from the midgut and hindgut. Although the term “foregut” is typically used in reference to the anterior section of the primitive gut, components of the adult gut can also be described with this designation. Pain in the epigastric region, just below the intersection of the ribs, typically refers to structures in the adult foregut.
The cloacal membrane is the membrane that covers the embryonic cloaca during the development of the urinary and reproductive organs.
In human anatomy, the median umbilical ligament is an unpaired midline ligamentous structure upon the lower inner surface of the anterior abdominal wall. It is covered by the median umbilical fold.
The bilaminar embryonic disc, bilaminar blastoderm or embryonic disc is the distinct two-layered structure of cells formed in an embryo. In the development of the human embryo this takes place by day eight. It is formed when the inner cell mass, also known as the embryoblast, forms a bilaminar disc of two layers, an upper layer called the epiblast and a lower layer called the hypoblast, which will eventually form into fetus. These two layers of cells are stretched between two fluid-filled cavities at either end: the primitive yolk sac and the amniotic sac.
Human embryonic development, or human embryogenesis, is the development and formation of the human embryo. It is characterised by the processes of cell division and cellular differentiation of the embryo that occurs during the early stages of development. In biological terms, the development of the human body entails growth from a one-celled zygote to an adult human being. Fertilization occurs when the sperm cell successfully enters and fuses with an egg cell (ovum). The genetic material of the sperm and egg then combine to form the single cell zygote and the germinal stage of development commences. Embryonic development in the human, covers the first eight weeks of development; at the beginning of the ninth week the embryo is termed a fetus. The eight weeks has 23 stages.
The development of the reproductive system is the part of embryonic growth that results in the sex organs and contributes to sexual differentiation. Due to its large overlap with development of the urinary system, the two systems are typically described together as the urogenital or genitourinary system.
The urorectal septum is an invagination of the cloaca. It divides it into a dorsal part and a ventral part. It invaginates from cranial to caudal, formed from the endodermal cloaca, and fuses with the cloacal membrane. Malformations can cause fistulas.
The connecting stalk, or body stalk is an embryonic structure that is formed by the third week of development and connects the embryo to its shell of trophoblasts. The connecting stalk is derived from the extraembryonic mesoderm. Initially it lies caudally to the trilaminar germ disc, but, with subsequent embryonic folding, the body stalk assume a more ventral position. Progressive expansion of the amnion from the umbilical ring creates a tube with a covering of amniotic membrane with allantois and umbilical vessels as its content and mesoderm of the connecting stalk as the ground substance. This extraembryonic mesodermal ground substance forms the future wharton's jelly. The amniotic membrane and its contents form the umbilical cord that connects the embryo and the placenta.
The development of the digestive system in the human embryo concerns the epithelium of the digestive system and the parenchyma of its derivatives, which originate from the endoderm. Connective tissue, muscular components, and peritoneal components originate in the mesoderm. Different regions of the gut tube such as the esophagus, stomach, duodenum, etc. are specified by a retinoic acid gradient that causes transcription factors unique to each region to be expressed. Differentiation of the gut and its derivatives depends upon reciprocal interactions between the gut endoderm and its surrounding mesoderm. Hox genes in the mesoderm are induced by a Hedgehog signaling pathway secreted by gut endoderm and regulate the craniocaudal organization of the gut and its derivatives. The gut system extends from the oropharyngeal membrane to the cloacal membrane and is divided into the foregut, midgut, and hindgut.
This article incorporates text in the public domain from page 1109 of the 20th edition of Gray's Anatomy (1918)