Gentamicin 2'-N-acetyltransferase

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gentamicin 2'-N-acetyltransferase
Identifiers
EC no. 2.3.1.59
CAS no. 50864-40-9
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MetaCyc metabolic pathway
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In enzymology, a gentamicin 2'-N-acetyltransferase (EC 2.3.1.59) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + gentamicin C1a CoA + N2'-acetylgentamicin C1a

Thus, the two substrates of this enzyme are acetyl-CoA and gentamicin C1a, whereas its two products are CoA and N2'-acetyl gentamicin C1a.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:gentamicin-C1a N2'-acetyltransferase. Other names in common use include gentamicin acetyltransferase II, gentamicin 2'-N-acetyltransferase, and acetyl-CoA:gentamicin-C1a N2'-acetyltransferase.

Related Research Articles

<span class="mw-page-title-main">Gentamicin</span> Antibiotic medication

Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not effective for gonorrhea or chlamydia infections. It can be given intravenously, by intramuscular injection, or topically. Topical formulations may be used in burns or for infections of the outside of the eye. It is often only used for two days until bacterial cultures determine what specific antibiotics the infection is sensitive to. The dose required should be monitored by blood testing.

<span class="mw-page-title-main">Acetyl-CoA C-acetyltransferase</span> Class of enzymes

In enzymology, an acetyl-CoA C-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an aminoglycoside N3'-acetyltransferase (EC 2.3.1.81) is an enzyme that catalyzes the chemical reaction

In enzymology, an aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) is an enzyme that catalyzes the chemical reaction

In enzymology, an arylamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an aspartate N-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Carnitine O-acetyltransferase</span> Enzyme

Carnitine O-acetyltransferase also called carnitine acetyltransferase is an enzyme that encoded by the CRAT gene that catalyzes the chemical reaction

In enzymology, a cysteine-S-conjugate N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a D-amino-acid N-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Diamine N-acetyltransferase</span>

In enzymology, a diamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a diaminobutyrate acetyltransferase (EC 2.3.1.178) is an enzyme that catalyzes the chemical reaction

In enzymology, a D-tryptophan N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a gentamicin 3'-N-acetyltransferase (EC 2.3.1.60) is an enzyme that catalyzes the chemical reaction

In enzymology, a glutamate N-acetyltransferase (EC 2.3.1.35) is an enzyme that catalyzes the chemical reaction

In enzymology, an imidazole N-acetyltransferase is an enzyme that catalyzes the chemical reaction

acetyl-CoA + imidazole CoA + N-acetylimidazole

In enzymology, a leucine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a N-acetylneuraminate 4-O-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a N-acetylneuraminate 7-O(or 9-O)-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a peptide alpha-N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a tetrahydrodipicolinate N-acetyltransferase (EC 2.3.1.89) is an enzyme that catalyzes the chemical reaction

References


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