Glucosamine N-acetyltransferase

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glucosamine N-acetyltransferase
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Glucosamine N-acetyltransferase homodimer, Rhizomucor miehei
Identifiers
EC no. 2.3.1.3
CAS no. 9032-94-4
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In enzymology, a glucosamine N-acetyltransferase (EC 2.3.1.3) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + D-glucosamine CoA + N-acetyl-D-glucosamine

Thus, the two substrates of this enzyme are acetyl-CoA and D-glucosamine, whereas its two products are CoA and N-acetyl-D-glucosamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine N-acetyltransferase. Other names in common use include glucosamine acetylase, and glucosamine acetyltransferase. This enzyme participates in aminosugars metabolism.

Related Research Articles

<span class="mw-page-title-main">N-acetyltransferase</span>

N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. N-acetyltransferases are cytosolic enzymes found in the liver and many tissues of most mammalian species, except the dog and fox, which cannot acetylate xenobiotics.

Aralkylamine <i>N</i>-acetyltransferase Class of enzymes

Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The gene is translated into a 23 kDa large enzyme. It is well conserved through evolution and the human form of the protein is 80 percent identical to sheep and rat AANAT. It is an acetyl-CoA-dependent enzyme of the GCN5-related family of N-acetyltransferases (GNATs). It may contribute to multifactorial genetic diseases such as altered behavior in sleep/wake cycle and research is on-going with the aim of developing drugs that regulate AANAT function.

<span class="mw-page-title-main">N-acetylglucosamine-6-sulfatase</span> Protein-coding gene in the species Homo sapiens

N-acetylglucosamine-6-sulfatase (EC 3.1.6.14, glucosamine (N-acetyl)-6-sulfatase, systematic name N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase) is an enzyme that in humans is encoded by the GNS gene. It is deficient in Sanfilippo Syndrome type IIId. It catalyses the hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate

In enzymology, an aminoglycoside N3'-acetyltransferase (EC 2.3.1.81) is an enzyme that catalyzes the chemical reaction

In enzymology, an arylamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a D-amino-acid N-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Diamine N-acetyltransferase</span>

In enzymology, a diamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a D-tryptophan N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a glucosamine-1-phosphate N-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Glucosamine-phosphate N-acetyltransferase</span>

In enzymology, glucosamine-phosphate N-acetyltransferase (GNA) is an enzyme that catalyzes the transfer of an acetyl group from acetyl-CoA to the primary amine in glucosamide-6-phosphate, generating a free CoA and N-acetyl-D-glucosamine-6-phosphate.

In enzymology, a maltose O-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a N-acetylneuraminate 7-O(or 9-O)-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a peptide alpha-N-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Serine O-acetyltransferase</span>

In enzymology, a serine O-acetyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</span> Class of enzymes

In enzymology, an UDP-N-acetylglucosamine 1-carboxyvinyltransferase is an enzyme that catalyzes the first committed step in peptidoglycan biosynthesis of bacteria:

In enzymology, a beta-galactoside alpha-2,6-sialyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase is an enzyme that catalyzes the chemical reaction

UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase is an enzyme with systematic name acetyl-CoA:UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase. This enzyme catalyses the following chemical reaction

UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine transaminase is an enzyme with systematic name UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine:2-oxoglutarate aminotransferase. This enzyme catalyses the following chemical reaction

References