| Glycosyl hydrolases family 31 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 structure of the yici thiosugar michaelis complex | |||||||||
| Identifiers | |||||||||
| Symbol | Glyco_hydro_31 | ||||||||
| Pfam | PF01055 | ||||||||
| Pfam clan | CL0058 | ||||||||
| InterPro | IPR000322 | ||||||||
| PROSITE | PDOC00120 | ||||||||
| CAZy | GH31 | ||||||||
| Membranome | 523 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 31 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. [1] [2] [3] This classification is available on the CAZy web site, [4] [5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. [6] [7]
Glycoside hydrolase family 31 CAZY GH_31 comprises enzymes with several known activities; alpha-glucosidase (EC 3.2.1.20), alpha-galactosidase (EC 3.2.1.22); glucoamylase (EC 3.2.1.3), sucrase-isomaltase (EC 3.2.1.48) (EC 3.2.1.10); alpha-xylosidase (EC 3.2.1); alpha-glucan lyase (EC 4.2.2.13).
Glycoside hydrolase family 31 groups a number of glycosyl hydrolases on the basis of sequence similarities [8] [9] [10] An aspartic acid has been implicated [11] in the catalytic activity of sucrase, isomaltase, and lysosomal alpha-glucosidase.
